High-fat diets cause more damage to metabolic health than carbohydrates
In recent years, many media reports and social media influencers have emphasized the dangers of eating too many…
Normal BMI hides nutritional gaps in alcohol use disorder
A sweeping review shows that while calorie intake and BMI often appear normal in people with alcohol use…
Dynamic viral markers predict treatment response in hepatitis B
Background and aims The rate of functional cure (HBsAg loss) remains unsatisfactory following pegylated interferon (PEG-IFN) treatment in…
ERC Proof of Concept grant supports promising CRISPR-based cancer treatment research
Microbiologist John van der Oost of Wageningen University & Research (WUR) has received an ERC Proof of Concept…
Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps…
Bacterial infections in patients with liver cirrhosis show rising prevalence and high mortality
Background and aims Bacterial infections (BIs) are common and severe complications in patients with liver cirrhosis, but global…
New study identifies the optimal exercise dose for reducing hepatic steatosis
Hepatic steatosis is a core pathological feature of metabolic dysfunction-associated steatotic liver disease (MASLD). It not only drives…
Chemotherapy-induced gut changes trigger anti-metastatic immune response
Chemotherapy commonly damages the intestinal lining, a well-known side effect. But this injury does not remain confined to…
Study shows DHPS enzyme controls macrophage maturation across multiple organs
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
Reducing alcohol consumption could significantly lower cancer deaths
Reducing annual alcohol consumption in Australia by one litre a person could significantly lower deaths from several major…
Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia…
Preclinical study reveals potential new treatment for severe liver fibrosis
Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis – a dangerous, disease-induced build-up of…