Targeting lipid enzymes triggers starvation states in aggressive tumor cells
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for…
FDA-approved drug fedratinib enhances communication between cellular organelles
Cells behave like cities and organelles carry out infrastructural roles: Mitochondria are powerhouses, the endoplasmic reticulum serves as…
Imaris 11 transforms image analysis
In this interview, NewsMed speaks with Georgia Golfis, European Imaris Team Representative, about the launch of Imaris 11…
Tuberculosis bacteria stiffen cell membranes to evade immune destruction
Scientists have uncovered an elegant biophysical trick that tuberculosis-causing bacteria use to survive inside human cells, a discovery…
New atlas of brain lysosomes sheds light on neurodegenerative disorders
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when…
Changes in brain fats play a key role in Alzheimer’s development and progression
More than a century ago, Alois Alzheimer noted unusual changes in brain fats, which he described as “lipoid…
Mitochondria and lysosomes work together to control regulatory T cell activation
Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the…
Lysosomal activity in worms linked to transgenerational extension of lifespan
In the Wang Lab, it’s not unusual for worms to live for a long time. HHMI Janelia Research…
Lysosomal acidity fine-tunes reactive species production in macrophages
Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis.…