Pen-strep treatment rewires mechanical sensing in immune cells
Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to…
TREM2 helps macrophages survive and repair radiation damaged skin
Recently, teams led by Prof. Yiming Zhang from Xinqiao Hospital, Army Medical University,Prof. Fazhi Qi from Zhongshan Hospital,…
Targeted PET/CT tracer improves early prediction of treatment response in rheumatoid arthritis patients
A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients in as little as four…
Engineered Listeria boosts innate immunity against cancer
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system…
Study shows DHPS enzyme controls macrophage maturation across multiple organs
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
Tattoo ink alters immune cells and weakens some vaccine responses
New research reveals that tattoo pigments don’t just stay in the skin, they migrate into lymph nodes, trigger…
How walnuts combat inflammation and oxidative stress in the body
From protecting brain cells to modulating immunity, walnut bioactives demonstrate remarkable antioxidant and anti-inflammatory potential; however, scientists caution…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Lysosomal acidity fine-tunes reactive species production in macrophages
Macrophages rely on lysosomes to balance microbial killing with self-protection, generating reactive oxygen and nitrogen species during phagocytosis.…