New structural insights overturn old assumptions about malaria entry
For nearly half a century, scientists have known that malaria parasites force their way into human red blood cells through a…
Study uncovers self-propelled actin filaments that shape living cells
Every time a white blood cell engulfs a bacterium, a neuron extends a projection to connect with a…
Protein-sharing helps dormant bacteria withstand antibiotic treatment
When bacteria are under antibiotic attack, it is not ‘every man for himself.’ Researchers at Baylor College of…
Scientists unlock molecular structure of key protein linked to cancer, neurological diseases
After nearly four decades of research, Mayo Clinic scientists have revealed the molecular structures of protein kinase C beta (PKCβ),…
New pico-calorimeter detects antibiotic resistance via direct heat traces
When living cells grow, divide, or respond to drugs, they give off tiny amounts of heat that offer…
New single-protein analysis technique provides unprecedented information on scramblases
A new single-protein analysis technique gives researchers an unprecedented ability to study proteins called scramblases, which have critical…
PSMA PET detects high-risk prostate cancer bone metastases
Compared to conventional imaging techniques, prostate specific membrane antigen (PSMA) PET imaging provides superior detection of bone metastases…
Predictive model helps tailor PSMA therapy for prostate cancer patients
A new machine-learning approach for prostate-specific membrane antigen (PSMA) treatment of metastatic castration-resistant prostate cancer (mCRPC) could estimate…
Targeting lipid enzymes triggers starvation states in aggressive tumor cells
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for…
Light-driven nanomotors improve multimodal breast cancer treatment efficacy
The nanomotor starts with bowl‑shaped mesoporous polydopamine (PDA) nanoparticles. These biocompatible bowls are loaded with two key payloads:…
AI-based generative framework create all-atom models of proteins in motion
Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins. When molecules of a drug…
UCLA researchers build programmable artificial organelles using RNA
Just as the human body relies on organs such as the heart or liver for essential functions, cells…