AlphaFold Database expands with millions of predicted protein complexes
A new collaboration between EMBL’s European Bioinformatics Institute (EMBL-EBI), Google DeepMind, NVIDIA, and Seoul National University has made…
Study reveals how disordered proteins function without stable structure
A new LMU study shows how proteins function reliably even without a stable 3D structure – and the…
A membrane-bound nuclease directly cleaves phage DNA during genome injection
Growth conditions and strains All the strains, phages, plasmids and oligonucleotides used in this study are listed in…
Neuron lattice structure may guard against neurodegeneration
Brain cells are constantly swallowing material from the fluid that surrounds them – signaling molecules, nutrients, even pieces of their own surfaces – in a process…
AI uncovers evolution of genetic control elements in mammalian cerebellum
Artificial intelligence allows tracing the evolution of genetic control elements in the developing mammalian cerebellum. An international research…
MYC cancer gene suppresses immune alarm signals to protect pancreatic tumors
The cancer gene MYC camouflages tumors by suppressing alarm signals that normally activate the immune system. This finding…
Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia…
Endonuclease V activated Pyrococcus furiosus Argonaute for the detection of food contaminated bacteria
Banada, P. P. et al. Label-free detection of multiple bacterial pathogens using light-scattering sensor. Biosens. Bioelectron. 24, 1685–1692…
New insights into the global expansion of Candida auris
The fungal species Candida auris is spreading across the globe, and gaining in virulence, according to a new…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
Opposing protein forces fine tune mRNA stability in human cells
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders…
Virus shells use asymmetry to control RNA release and infection
Viruses are typically described as tiny, perfectly geometric shells that pack genetic material with mathematical precision, but new…