The expanding landscape of GLP-1 medicines
Drucker, D. J., Philippe, J., Mojsov, S., Chick, W. L. & Habener, J. F. Glucagon-like peptide I stimulates…
Determining the value of genomics in healthcare
Stark, Z. et al. Integrating genomics into healthcare: a global responsibility. Am. J. Hum. Genet 104, 13–20 (2019).…
Multienzymatic nanocatalysts attenuate acute pancreatitis via dual modulation of pyroptotic pathways and autodigestion blockade | Journal of Nanobiotechnology
Iannuzzi JP, King JA, Leong JH, Quan J, Windsor JW, Tanyingoh D, et al. Global incidence of acute…
Multidomain therapy for Alzheimer’s disease: a scoping review of cognitive decline trials | Molecular Neurodegeneration
Sikkes SAM, Tang Y, Jutten RJ, Wesselman LMP, Turkstra LS, Brodaty H, Clare L, Cassidy-Eagle E, Cox KL,…
C-terminus-dependent detection of lysosomal alpha-synuclein in nigral Parkinson’s disease human brain neurons | Molecular Neurodegeneration
Maroteaux L, Campanelli JT, Scheller RH. Synuclein – a neuron-specific protein localized to the nucleus and presynaptic nerve-terminal.…
Transcranial and precise optical neuromodulation mediated by NIR photoactive nanosheets | Journal of Nanobiotechnology
Materials Ti3AlC2 was supplied by Zhongke Experimental Materials Co., Ltd. (China). Ethyl alcohol, HCl, and lithium fluoride (LiF)…
A full life cycle biological clock based on routine clinical data and its impact in health and diseases
Study populations The China Health Aging Investigation (CHAI), as a project of the International Consortium of Digital Twin…
Dual-function MgSrCeAl-LDH nanosheets enable both ROS clearance and enhanced angiogenesis for myocardial ischemia/reperfusion injury therapy | Journal of Nanobiotechnology
Materials Magnesium nitrate hexahydrate (Mg(NO3)2·6H2O, > 99.0%), aluminum nitrate nonahydrate (Al(NO3)2·9H2O, > 99.0%), strontium nitrate (Sr(NO3)2, > 99.0%), cerium nitrate hexahydrate…
Entering the era of precision medicine to treat amyotrophic lateral sclerosis | Molecular Neurodegeneration
Goutman SA, Hardiman O, Al-Chalabi A, Chió A, Savelieff MG, Kiernan MC, Feldman EL. Emerging insights into the…
Brain somatic mutations in Alzheimer’s disease: linking genetic mosaicism to neurodegeneration | Molecular Neurodegeneration
Zhang XX, Tian Y, Wang ZT, Ma YH, Tan L, Yu JT. The epidemiology of alzheimer’s disease modifiable…
Rapid in situ microwave-assisted fabrication of ultrabright near-infrared probe for low-dose in vivo inflammatory imaging | Journal of Nanobiotechnology
Preparation and characterization of Ag2S super NPs Microwaves, a kind of nonionizing electromagnetic energy, exhibits a spectral frequency…
Synthetic lethality in cancer drug discovery: challenges and opportunities
Hartwell, L. H., Szankasi, P., Roberts, C. J., Murray, A. W. & Friend, S. H. Integrating genetic approaches…