Primary cilia as regulators of fibrosis and potential therapeutic targets
Lee, J. et al. Increased primary cilia in idiopathic pulmonary fibrosis. Mol. Cells. 41, 224–233 (2018). CAS PubMed …
Real-world, digital-first delivery of GLP-1 receptor agonist therapy in women
Study population Between 27 November 2024 and 31 January 2025, adult women (female sex at birth) were recruited…
Hypoxia-induced HMGB1/NLRP3/Caspase-1 signaling axis enhances proliferation of oral squamous cell carcinoma
Miranda-Filho A, Bray F. Global patterns and trends in cancers of the lip, tongue and mouth. Oral Oncol.…
An open vision-language model for diverse medical applications
MedGemma performance across medical text and imaging benchmarks MedGemma performance was evaluated across several medical text and medical…
Probing the many benefits of GLP-1 receptor agonists
RESEARCH HIGHLIGHT 05 October 2026 Glucagon-like peptide 1 (GLP-1) receptor agonists are approved for the treatment of type…
The cellular landscape of druggable RNA-binding proteins
Gerstberger, S., Hafner, M. & Tuschl, T. A census of human RNA-binding proteins. Nat. Rev. Genet. 15, 829–845…
Initial lessons from real-world implementation of an AI-agent eye clinic in China
These authors contributed equally: Tao Yan, Di Zhang. Department of Automation, Tsinghua University, Beijing, China Tao Yan, Taizhangtian Ma, Chunyang…
Phenomic profiles and disease patterns of 1.9 million participants from Our Future Health
Ethical approval This study involves data from human participants that have participated in the OFH program and the…
Prospective evaluation of a large language model clinical decision support system in the emergency department
Hoot, N. R. & Aronsky, D. Systematic review of emergency department crowding: causes, effects, and solutions. Ann. Emerg.…
Psilocybin-assisted therapy for treatment-resistant major depressive disorder in a public healthcare setting: a randomized controlled trial
This study of psilocybin assisted-therapy for TRD—to our knowledge, the first RCT in this population to assess feasibility…
Divergent impacts of explainable AI for dermatological diagnosis on clinicians versus lay people
Study design We designed two complementary large-scale experiments to evaluate human−AI collaborative diagnostic performance across expertise levels (Fig.…
Integrated care pathway in individuals with Long COVID: STIMULATE-ICP, a cluster-randomized, phase 3 trial
Trial design and oversight The STIMULATE-ICP trial aimed to investigate the efficacy of an enhanced ICP for LC,…