Kura Oncology launches diabetes-focused Caspian Therapeutics
Just under a year after netting its first US approval for a cancer-fighting menin inhibitor, Kura Oncology…
New study uncovers bacterial route to testosterone production
Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease…
Gut bacterial molecule discovered to drive serious bile duct disease
Researchers at the University of Oslo and Oslo University Hospital have, together with international collaborators, discovered that a…
Modified AlphaFold3 successfully predicts complex protein conformational changes
Conformational changes in proteins are vital to their function yet remain challenging for state-of-the-art artificial intelligence, such as…
Fleeting interactions between membrane sugar chains control cell division
Acting as an armor, a scaffold, and a communication platform in one, our cells’ plasma membrane lies at…
Computer model could streamline design of protein degraders
A team of Weill Cornell Medicine investigators has developed a computer model that will help scientists more efficiently…
Scientists uncover tRNA changes driving Chagas parasite transformation
The Chagas disease parasite (Trypanosoma cruzi) undergoes a major transformation throughout its life cycle in order to infect…
Polydatin reduces ulcerative colitis by regulating intestinal immune cells
Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which recurrent intestinal inflammation can be difficult to…
Sprint exercise sends a very different molecular signal through the body
Just minutes of all-out sprint work produced a striking surge in circulating proteins and metabolites, revealing how exercise…
Natural gut molecule ould strengthen chickens’ immune response against bacterial infections
A naturally occurring gut molecule that could strengthen chickens’ immune response against a wide range of bacterial infections,…
New study uncovers metabolic vulnerability in high-risk myelodysplastic syndromes
Researchers at the University of Colorado Anschutz Cancer Center have identified a previously unknown metabolic weakness in the…
Novel drug puts cancer cells under extreme metabolic stress
Cancer cells have a voracious appetite for sugar-using it to fuel their rapid growth. This is why many…