High expression of CTDNEP1 gene linked to poorer kidney cancer survival
Renal cell carcinoma (RCC) is the most common form of kidney cancer, accounting for about 90% of kidney…
Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system
One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but…
Single-molecule imaging reveals nucleated growth mechanism of viral capsids
Oxford University researchers have captured the step-by-step assembly of individual virus-like particles, revealing how simple molecular interactions can…
Kura Oncology launches diabetes-focused Caspian Therapeutics
Just under a year after netting its first US approval for a cancer-fighting menin inhibitor, Kura Oncology…
New study uncovers bacterial route to testosterone production
Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease…
Gut bacterial molecule discovered to drive serious bile duct disease
Researchers at the University of Oslo and Oslo University Hospital have, together with international collaborators, discovered that a…
Modified AlphaFold3 successfully predicts complex protein conformational changes
Conformational changes in proteins are vital to their function yet remain challenging for state-of-the-art artificial intelligence, such as…
Fleeting interactions between membrane sugar chains control cell division
Acting as an armor, a scaffold, and a communication platform in one, our cells’ plasma membrane lies at…
Computer model could streamline design of protein degraders
A team of Weill Cornell Medicine investigators has developed a computer model that will help scientists more efficiently…
Scientists uncover tRNA changes driving Chagas parasite transformation
The Chagas disease parasite (Trypanosoma cruzi) undergoes a major transformation throughout its life cycle in order to infect…
Polydatin reduces ulcerative colitis by regulating intestinal immune cells
Ulcerative colitis (UC) is a chronic inflammatory bowel disease in which recurrent intestinal inflammation can be difficult to…
Sprint exercise sends a very different molecular signal through the body
Just minutes of all-out sprint work produced a striking surge in circulating proteins and metabolites, revealing how exercise…