Evolutionary noncoding RNAs reveal new targets for cancer therapy
In cancer research, one person’s junk is increasingly becoming another person’s treasure. Scientists have now uncovered new evidence…
New screening approach identifies proteins that control human gene expression
Researchers at University of California San Diego have developed a large-scale screening approach that identifies proteins controlling a…
Cone opsin structures offer insights into vision loss
The retina of the human eye contains six to seven million cone cells. These cells contain light-sensitive proteins…
Duke researchers discover molecules that target vital cell signaling proteins
To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive…
Prime and pull vaccine approach prevents genital herpes infection
Genital herpes is a lifelong infection. While available treatments can manage symptoms, they cannot cure the infection or…
Neutrophils reduce the effectiveness of cancer immunotherapy in mice
A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less…
AI breakthrough accelerates molecular simulations for drug discovery
A new AI model has become so good at predicting how molecules evolve over time that, in the…
New antibiotic from soil bacteria targets drug-resistant superbugs
Scientists at the University of Illinois Chicago have discovered a new antibiotic that may be a bulwark in the fight…
Study potentially opens a new route to more selective cancer drug design
Researchers at the Icahn School of Medicine at Mount Sinai have identified a previously hidden druggable site in…
Small non-coding RNA molecule precisely controls vital gene expression and cellular balance
A rapidly advancing area of biomedical innovation is shining a spotlight on miR-128-3p, a small yet powerful molecule…
Polymer-based immunotherapies enhance tumor targeting and immune activation
Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less…
Scientists uncover cellular mechanism behind rare childhood brain disorders
Thousands of times per year, a family’s moment of joy turns to unexpected grief. A seemingly healthy infant…