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Browsing Tag

Neurodegeneration

57 posts
HHealth
Image of neuron and intracellular proteins.
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Can GLP-1 Drugs Treat Parkinson’s Disease? What Research Shows

  • October 16, 2026
IntroductionTargeting the biological drivers of PDHow GLP-1 drugs may protect dopaminergic neuronsEarly evidence of neuroprotectionClinical trial evidenceInsights from…
SScience
Review: Gut Microbiome-Mediated Neuroprotective Effect of the Mediterranean Diet: A Narrative Review of Cognitive Aging, Alzheimer’s Disease, and Parkinson’s Disease. Image Credit: LipeBorges_Foto / Shutterstock
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Could the Mediterranean diet protect the brain through the gut?

  • September 28, 2026
From microbial metabolites to inflammation and the blood-brain barrier, researchers trace how Mediterranean eating could influence neurodegeneration, while…
SScience
NSF awards $19 million to build 3D biological observatory for revealing life's smallest structures
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NSF awards $19 million to build 3D biological observatory for revealing life’s smallest structures

  • September 24, 2026
How does learning change the wiring of your brain? How does a shark’s eye make sense of its…
HHealth
Landmark map of human brain’s gene activity holds clues to Alzheimer’s disease and more
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Landmark map of human brain’s gene activity holds clues to Alzheimer’s disease and more

  • September 24, 2026
A detailed brain map describes gene activity in neurons (artist’s illustration) as well as immune and vascular cells…
HHealth
Map of brain ‘microproteins’ could offer new clues to Alzheimer’s disease
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Map of brain ‘microproteins’ could offer new clues to Alzheimer’s disease

  • September 16, 2026
Mapping microproteins in the brain might help to understand, and treat, Alzheimer’s disease.Credit: Zephyr/SPL More than 1,000 previously…
HHealth
Picture: Getty Images for unsplash
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Teitur Trophics reports positive phase 1 data for Parkinson’s peptide

  • September 10, 2026
Why it matters: Parkinson’s treatments can help manage symptoms, but none has been shown to slow or stop…
HHealth
Study: Priming of CD8+ T cells by peripheral dendritic cells exacerbates tau-mediated neurodegeneration. Image Credit: Antonio Marca / Shutterstock
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Scientists traced a hidden immune route that may worsen tau-linked brain damage

  • September 7, 2026
Researchers traced an immune pathway from brain-draining lymph nodes to tau-affected tissue, revealing how peripheral immune activity may…
HHealth
Compact bNIRS technology could become a diagnostic toolkit for dementia
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Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration

  • August 27, 2026
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the…
HHealth
Immune cells communicate across a continuous, bidirectional circuit between the CNS and periphery. Immune cells from across the body engage CNS tissues and, in turn, are shaped by signals returning from the brain. (Left) Under peripheral equilibrium, immune effectors mobilized from visceral organs, secondary lymphoid organs, hematopoietic tissues, and the peripheral nervous system (PNS) - including CD4+ and CD8+ T cells, B cells, monocytes (top 3 cell types), NK cells, dendritic cells, mast cells, neutrophils, and innate lymphoid cells (bottom cluster of cells) - engage the CNS in a homeostatic dialogue that supports neural cell health, plasticity, and repair, sustaining a protective environment. (Right) Age-associated dysfunction across the same peripheral compartments reshapes this circuit: altered immune effectors enter the CNS and contribute to shifting the local environment toward a degenerative state in which microglia adopt disease-associated programs, astrocytes become reactive, and neurons accumulate pathology. This model underscores how the same circuitry can yield protective or pathogenic outcomes and that neurodegeneration is downstream of dysfunctional brain-immune crosstalk. Study: Neurodegeneration as a dysregulation of neuroimmune crosstalk
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Disrupted brain-immune signaling may help drive neurodegeneration

  • August 24, 2026
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
HHealth
Study analyzes alterations in the cerebral cortex in people with psychosis
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Study connects late-life psychosis to abnormal tau protein buildup

  • August 4, 2026
Hallucinations and delusions that appear for the first time in midlife or later are often treated as psychiatric…
HHealth
Study: AI-redesigned starting points and outcomes enhance protein evolution. Image Credit: Corona Borealis Studio / Shutterstock
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AI redesign helps enzymes evolve beyond natural limits

  • July 24, 2026
By stabilizing enzyme starting points before evolution, researchers opened new mutational routes for engineering highly specific proteases, including…
HHealth
Frequent TV watching links to higher white matter lesion volume
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Frequent TV watching links to higher white matter lesion volume

  • July 23, 2026
A 24-year ARIC analysis suggests that the setting in which people sit may matter for brain measures linked…
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