Teitur Trophics reports positive phase 1 data for Parkinson’s peptide
Why it matters: Parkinson’s treatments can help manage symptoms, but none has been shown to slow or stop…
Scientists traced a hidden immune route that may worsen tau-linked brain damage
Researchers traced an immune pathway from brain-draining lymph nodes to tau-affected tissue, revealing how peripheral immune activity may…
Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the…
Disrupted brain-immune signaling may help drive neurodegeneration
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
Study connects late-life psychosis to abnormal tau protein buildup
Hallucinations and delusions that appear for the first time in midlife or later are often treated as psychiatric…
AI redesign helps enzymes evolve beyond natural limits
By stabilizing enzyme starting points before evolution, researchers opened new mutational routes for engineering highly specific proteases, including…
Frequent TV watching links to higher white matter lesion volume
A 24-year ARIC analysis suggests that the setting in which people sit may matter for brain measures linked…
Sleeping longer may signal early Alzheimer’s-related brain changes
Regularly sleeping long hours each night is associated with higher levels of an Alzheimer’s-related protein in the blood,…
Longer hormone exposure linked to healthier brain aging in women
Women with a history of hormonal birth control, menopausal hormone therapy, or later menopause showed structural brain differences…
Iron overload gradually increases neurons’ vulnerability to neurodegeneration
Neurodegenerative diseases affect tens of millions of people worldwide. Among these, Alzheimer’s and Parkinson’s diseases are the most…
Peacemaker immune cells offer new hope for restoring immune tolerance
‘Peacemaker’ immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a…
Scientists reveal how cGAS-STING fuels brain inflammation and neurodegeneration
A major immune pathway once known for detecting DNA damage is now being linked to brain aging, glial…