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Browsing Tag

Neurodegenerative Diseases

46 posts
HHealth
Study uncovers three-way relationships between gut fungi, genetics and disease risk
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Researchers uncover new genetic links influencing blood lipid composition

  • May 20, 2026
DZNE researchers have generated new insights into how the human genome shapes the chemical composition and concentration of…
TTechnology
Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia
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L-arginine stabilizes protein droplets and prevents harmful fibril formation

  • April 24, 2026
Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer’s, these liquid-like droplets can…
HHealth
Compact bNIRS technology could become a diagnostic toolkit for dementia
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New human cell model replicates key mechanisms of neurodegenerative diseases

  • April 23, 2026
Researchers at LMU have developed a human cell model that replicates key mechanisms of neurodegenerative diseases – with…
HHealth
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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Microglia actively shape glioblastoma growth and tumor spread

  • April 22, 2026
Glioblastoma, the most common and most aggressive brain tumor type in adults, remains difficult to treat because it…
HHealth
Study highlights the emotional and social challenges of stroke recovery
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Having more children associated with lower stroke risk for women

  • April 21, 2026
While some say having lots of kids can make you lose your faculties, a new study suggests otherwise.…
HHealth
Proteomics analytical pipeline in precision medicine. Review: The emerging role of high-throughput proteomics in advancing precision medicine
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Proteomics and AI bring earlier risk prediction into sharper focus

  • April 20, 2026
From Alzheimer’s risk to cardiovascular prediction, this review shows how protein profiling and AI could help detect disease…
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
SScience
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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RNA barcoding maps neural connections with unprecedented resolution

  • April 8, 2026
By tagging neurons with molecular “barcodes,” researchers mapped connections among thousands of neurons in the mouse brain with…
SScience
Female-specific mechanism enhances heat production in brown fat
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Study reveals pearling mechanism behind mitochondrial DNA spacing

  • April 3, 2026
Mitochondria are often described as the cell’s power plants, because they generate energy. To help them achieve this,…
HHealth
Viewpont: The hidden world of nanoplastics colliding with neurodegenerative diseases. Image Credit: Maryshot / Shutterstock
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Scientists uncover nanoplastics in brain tissue and question their role in neurological disease

  • February 18, 2026
Scientists are detecting nanoplastics in human brain tissue and exploring how these particles may influence the risk of…
SScience
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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Neuron lattice structure may guard against neurodegeneration

  • February 12, 2026
Brain cells are constantly swallowing material from the fluid that surrounds them – signaling molecules, nutrients, even pieces of their own surfaces – in a process…
HHealth
Berberine improves cognitive function in diabetic encephalopathy mice
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Research uncovers why certain brain cells are more resilient to tau protein buildup

  • January 30, 2026
New research by UCLA Health and UC San Francisco has uncovered why certain brain cells are more resilient…
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