New atlas of brain lysosomes sheds light on neurodegenerative disorders
Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when…
Study reveals how ketogenic diet protects against epilepsy seizures
University of Virginia School of Medicine researchers have revealed how the popular, low-carb ketogenic diet protects against epilepsy…
MIT researchers map dynamic fuzzy coat surrounding tau protein fibrils
One of the hallmarks of Alzheimer’s disease is the clumping of proteins called Tau, which form tangled fibrils…
Opposing protein forces fine tune mRNA stability in human cells
A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and disorders…
New molecular ruler enables precise measurement of toxic Tau fibrils in fluid samples
Researchers have developed a new tool, FibrilPaint combined with the FibrilRuler test, that allows scientists to directly measure…
New analysis reveals fundamental flaws in widely used measures of biological aging
A landmark review published today in Genomic Psychiatry challenges researchers to fundamentally reconsider how the field measures and…
Discovery of smOOP RNAs reveals hidden rules of cellular phase separation
Inside cells, RNAs and proteins form tiny, liquid-like droplets called biomolecular condensates. These droplets are essential for organizing…
Can diet calm early memory problems? Anti-inflammatory Mediterranean eating shows promise
A powerful anti-inflammatory twist on the Mediterranean diet shows striking protection against early memory problems in older women,…
Cutting-edge treatments in amyotrophic lateral sclerosis: the role of molecular pathogenesis in targeted therapies | Stem Cell Research & Therapy
Feldman EL, Goutman SA, Petri S, Mazzini L, Savelieff MG, Shaw PJ, et al. Amyotrophic lateral sclerosis. Lancet.…
Polymer physics offers fresh perspectives on neurodegenerative diseases
Researchers from Tokyo Metropolitan University have applied ideas from polymer physics to illuminate the mechanism behind a key…
Preclinical study shows aged garlic extract improves memory and reduces anxiety
New findings show that aged garlic extract reshapes brain pathways tied to memory and emotion, revealing a promising…
Midlife blood test may reveal Alzheimer’s disease risk in advance
A simple blood test for platelet activity at middle age could one day help identify people at risk…