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Browsing Tag

Neurons

144 posts
HHealth
Innate immune activation and microglial transition during neurodegeneration. (A) During neurodegeneration, distressed neurons release DAMPs such as mtDNA, ROS, HMGB1, aberrant proteins, and pTau–bound RNA. These signals activate resident microglia and astrocytes, which then recruit peripheral immune cells. As shown in more detail in B, activated microglia upregulate PRRs, including TLRs, RAGE, and cGAS, enabling detection of neuron-derived DAMPs. Engagement of PRRs induces proinflammatory gene expression programs and activates inflammasome pathways that promote release of chemokines and cytokines into the CNS parenchyma. As microglia transition from homeostatic to reactive states in a TREM2-dependent manner, damage-associated microglia increase MHC-II expression to support antigen presentation and coordination of adaptive immune responses that attempt to limit neurodegeneration.
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How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases

  • April 17, 2026
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
HHealth
Early B cell response prevents Oropouche virus from reaching the brain
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Aston University bioscientist receives £125,000 to investigate genetic reasons for neurodegeneration

  • April 15, 2026
Aston University bioscientist Dr John Reynolds has won a £125,000 Springboard grant from the Academy of Medical Sciences…
TTechnology
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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Northwestern engineers create artificial neurons that communicate with living cells

  • April 15, 2026
Northwestern University engineers printed artificial neurons that don’t just imitate the brain – they talk to it. In…
HHealth
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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Study reveals interhemispheric brain circuit crucial for spatial memory

  • April 15, 2026
A team led by the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council…
SScience
Using sound waves to soften tumors and boost chemotherapy
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Stanford researchers create noninvasive way to deliver light deep inside the body

  • April 13, 2026
Light has an increasing number of applications in biology and medicine – it can be used to stimulate…
SScience
Cancer cells found to use ketones as alternate fuel for growth
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Damon Runyon supports young scientists driving cancer research innovation

  • April 12, 2026
The Damon Runyon Cancer Research Foundation has named 13 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and…
SScience
Unraveling the brain mechanisms behind social hierarchies in mice
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New research identifies neural sequence for odor navigation in worms

  • April 10, 2026
Animal behavior reflects a complex interplay between an animal’s brain and its sensory surroundings. Only rarely have scientists…
HHealth
Microglia among neurons
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Affecting a Signaling Pathway Alleviates Alzheimer’s in Mice

  • April 10, 2026
A new study shows that the overexpression of somatostatin (SST), a neuropeptide produced in neurons and acting mostly…
SScience
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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New 3D organoid model advances pediatric glioma research and treatment

  • April 10, 2026
A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor…
HHealth
Compact bNIRS technology could become a diagnostic toolkit for dementia
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Study reveals lung-brain link between smoking and neurodegeneration

  • April 9, 2026
The correlation between smoking and neurodegeneration is well-documented, with one study from 2011 finding heavy smoking in midlife was associated…
SScience
AI tool SeeMe detects hidden signs of consciousness in brain injury patients
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RNA barcoding maps neural connections with unprecedented resolution

  • April 8, 2026
By tagging neurons with molecular “barcodes,” researchers mapped connections among thousands of neurons in the mouse brain with…
HHealth
Unraveling the brain mechanisms behind social hierarchies in mice
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Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma

  • April 7, 2026
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into…
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