AI-based chest X-ray prioritization in the lung cancer diagnostic pathway: the LungIMPACT randomized controlled trial
This large, multisite randomized study has shown that AI prioritization of CXRs did not improve the speed of…
AI-based triage and decision support in mammography and digital tomosynthesis for breast cancer screening: a paired, noninferiority trial
Ethics approval All patients provided written informed consent before enrollment. This prospective clinical trial was compliant with the…
Effects of daily multivitamin–multimineral and cocoa extract supplementation on epigenetic aging clocks in the COSMOS randomized clinical trial
Wu, Z., Zhang, W., Qu, J. & Liu, G. H. Emerging epigenetic insights into aging mechanisms and interventions.…
A clinical environment simulator for dynamic AI evaluation
Goh, E. et al. Large language model influence on diagnostic reasoning: a randomized clinical trial. JAMA Netw. Open…
A daily multivitamin slows the ticking of epigenetic clocks – Nature
A daily multivitamin slows the ticking of epigenetic clocks NatureTaking multivitamin daily could help to slow biological ageing, study…
The global burden of mental and substance use disorders among adolescents and young adults
Blakemore SJ. Adolescence and mental health. Lancet. 2019;393:2030–1. Article PubMed Google Scholar Degenhardt L, Stockings E, Patton G,…
Digital mental health needs a purpose-driven approach
Pineda, B. S. et al. Updated taxonomy of digital mental health interventions: a conceptual framework. mHealth 9, 28…
PRIMARY-AI: outcomes-based standards to safeguard primary care in the AI era
School of Clinical Medicine, Beijing Tsinghua Changgung Hospital, Tsinghua Medicine, Tsinghua University, Beijing, China Dian Zeng, Zehua Jiang, Yiming Qin & Tien…
Positive bias in brain and behaviour as a mechanism of transcranial magnetic stimulation depression treatment
This study has been pre-registered (NCT04969549, https://clinicaltrials.gov/study/NCT04969549 and https://osf.io/rhxm2). A more detailed description of the methods can be…
Reliability of LLMs as medical assistants for the general public: a randomized preregistered study
The study employed a between-subjects design with three treatment groups and a control. Before the treatment phase, participants…
Scaling medical AI across clinical contexts
Jiang, L. Y. et al. Health system-scale language models are all-purpose prediction engines. Nature 619, 357–362 (2023). Article …
The role of brain health and resilience in reshaping trajectories of late-life neuropsychiatric disorders
Olshansky SJ, Passaro DJ, Hershow RC, Layden J, Carnes BA, Brody J, et al. A potential decline in…