Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the…
Scientists create brain organoids with distinct cortical regional identity
The human brain is often described as one of the most complex structures in biology, and much of…
Blocking ZFP36L2 protein may disrupt colorectal cancer metastatic growth
Digestion is hard on the cells that line the human gut, and they are constantly being shed and…
Study reveals how pushing and pulling forces drive blood vessel formation
How do blood vessels form to reliably supply the body with oxygen and nutrients? A research team at…
New tumor organoids strengthen precision oncology research
Significant advances have been made in the development of patient-derived tumor “organoids” for preclinical research, in two new…
Stem cell study uncovers molecular pathway for enamel regeneration
Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally. To…
New genetic screening method unlocks insights into human development
A new genetic screening method allows researchers to efficiently modulate individual genes across entire tissues and provides new…
New genetic driver found for rare small intestinal cancers
A signaling system known as the Wnt pathway plays a central role in how cells in the intestine…
Harnessing human brain cells to create biocomputers
JMIR Publications today released a feature story on the emerging field of biocomputing in its News and Perspectives…
Lab-grown brain models reveal how epilepsy drug alters fetal development
It is known that the antiepileptic drug valproate increases the risk of developmental disorders in unborn children. A…
New 3D organoid model advances pediatric glioma research and treatment
A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor…
New neural organoid system improves scalability and reproducibility for research
Neural organoids have been heralded as having huge potential for advancing our knowledge of the brain in several fields. These include exploring the responses of brain tissue to drugs,…