New biomarker predicts prognosis and treatment response in colorectal cancer
Determining the presence of a protein in non-tumor cells within the cancer microenvironment could be one of the keys to establishing prognosis…
Transcription Factors Form Continuous ‘Circuit’ That Regulates T-cell Exhaustion
Weiguo Cui, PhD, professor of Pathology in the Division of Experimental Pathology, was senior author of the study published in…
Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
Molecular test shows high sensitivity in detecting bile duct cancer
When patients develop a narrowing or blockage in the bile ducts – the tubes connecting the liver, gallbladder…
Key gene mutation disrupts the brain’s ability to update beliefs in schizophrenia patients
One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients…
Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Novel lipid bubble delivery shows promise for ALS treatment
A researcher at the University of Missouri has made a promising breakthrough in the quest to help people…
Stilbenoid gaylussacin modulates particulate matter-induced chromatin remodeling in macrophages to suppress chronic obstructive pulmonary disease
Chronic obstructive pulmonary disease (COPD), a leading cause of mortality worldwide, is characterized by chronic bronchitis and emphysema.1…
Concordance analysis of DNA and RNA profiling: The MD Anderson IMPACT2 study in precision oncology
Competing interests S.F. reports research support from Abbisko, Antengene, BeiGene, BeyongSpring Pharmaceuticals, BioAtla, Boehringer Ingelheim, CUE Biopharma, DEKA…
Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier
Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau…
IFN-γ identified as alzheimer’s disease blood biomarker
A new study uncovers interferon gamma as both a powerful blood-based signal of Alzheimer’s disease (AD) and a…
Rare brain disorder PSP highlighted by Rev. Jesse Jackson’s passing
The death of the Rev. Jesse Jackson has put a spotlight on progressive supranuclear palsy, a rare degenerative…