Cryo-EM reveals NPFFR1 activation and guides novel ligand design
This study investigates the molecular mechanisms underlying ligand recognition, subtype selectivity, and activation of neuropeptide FF receptor 1…
New findings show why the human intestine uniquely presents gluten to T cells
New evidence shows that human M cells act as fully fledged antigen-presenting cells, processing and presenting gluten peptides…
Arginine slows amyloid buildup and improves brain outcomes in Alzheimer’s disease models
New preclinical evidence shows that oral arginine reduces toxic amyloid structures and eases behavioral impairments in Alzheimer’s models,…
New fluorescent labeling method offers high precision and exceptional stability in living cells
A team of researchers at IOCB Prague headed by Dr. Tomáš Slanina has developed a new method for…
LassoESM accelerates discovery of therapeutic peptides
In the hunt for new therapeutics for cancer and infectious diseases, lasso peptides prove to be a catch.…
Genes play an active role in shaping the gut bacteria, study finds
New research from the University of Sydney’s Charles Perkins Centre has found that genes play an active role in shaping…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…