Rice University chemists develop cheaper way to synthesize drugs
Pharmaceutical drugs often rely on chemical compounds found in the body. Take phosphate, a common compound cells use…
Researchers uncover molecular switch controlling nutrient-driven cell growth
Cells carry their own growth switches. When enough nutrients-amino acids in particular-are available, cells flip this switch on…
Blocking nitric oxide suppresses tumor growth in aggressive pediatric neuroblastoma
The tumor begins before birth. Somewhere in the developing fetus, neural crest cells that should have matured into…
Study identifies PPP2R5C blood marker that may detect Alzheimer’s disease earlier
Researchers report that declining PPP2R5C levels in blood may signal early Alzheimer’s pathology, offering new insight into tau…
A shingles vaccine may delay dementia onset
A clever natural experiment in Canada suggests a routine shingles vaccine may do more than prevent rash. Instead,…
COVID-19 severity is linked to changes in mitochondrial DNA methylation
New evidence from Indian patients shows that severe COVID-19 is associated with distinct mitochondrial methylation signatures and altered…
New method reveals how human cells initiate DNA replication
When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process…
Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
Research uncovers ASPL’s critical role in stress granule life cycle
Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…