Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Cryo-EM provides real-time glimpse of cellular machinery reading DNA inside living organisms
All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the…
Airplane wastewater pilot shows how airports could track pathogens across borders
A bilateral US-UK pilot suggests airplane wastewater could help track pathogen movement through international travel, but broader airport…
What medicine-exposed rats reveal about the next urban zoonotic threat
A new study reveals that urban rats are absorbing human medicines from polluted environments, and these hidden pharmaceutical…
Chromosome abnormalities may help cancer cells resist treatment and spread
A new study led by NYU Langone Health researchers found that cancer cells are better able to resist…
Rat hepatitis E virus may be a hidden cause of hepatitis in humans
A growing body of evidence suggests that rat hepatitis E virus is spilling into humans more often than…
New method isolates true transcription factor targets in tuberculosis bacteria
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.…
Study reveals poxvirus’s unique DNA clamp for gene activation
A research team at the University of Würzburg has deciphered another aspect of poxviral gene activation. The study…
Engineered enzyme enables fast and accurate RNA synthesis
From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine. But as…
New diagnostic framework addresses challenges of rapidly-mutating RNA viruses
The rapid evolutionary dynamics of RNA viruses, driven by high mutation rates and the consequent formation of complex…
Scientists uncover new mechanism initiating gene transcription
Scientists at IOCB Prague are uncovering new details of gene transcription. They have identified a previously unknown molecular…
Scientists capture real-time action of antiviral drugs on herpes
Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works. The…