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Browsing Tag

Preclinical

40 posts
TTechnology
Novel RNA target offers hope for improving outcomes in patients with chronic limb ischemia
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Tumor-targeted chimeric drug increases efficacy and limits side effects

  • February 8, 2026
Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more…
TTechnology
Nurse injecting insulin in diabetic girl belly. Close up of young girl with type 1 diabetes taking insulin with syringe needle.
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Immune scaffold predicts onset weeks early

  • February 4, 2026
A retrievable immune scaffold reveals a 5–7 week presymptomatic window for tracking type 1 diabetes progression, long before…
SScience
Berberine improves cognitive function in diabetic encephalopathy mice
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Hippocampus reorganizes memories to anticipate future outcomes, study finds

  • January 30, 2026
A preclinical study published in Nature has found evidence that the hippocampus, the brain region that stores memory, also reorganizes…
HHealth
Study: Total and different types of olive oil consumption, gut microbiota, and cognitive function changes in older adults. Image Credit: Mehes Daniel / Shutterstock
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Olive oil type matters for cognition and gut health in older adults

  • January 27, 2026
A large cohort study suggests that not all olive oils are equal, with virgin olive oil showing favorable…
SScience
Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease
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Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

  • January 27, 2026
From protein misfolding to gut–brain signalling, emerging evidence suggests that everyday plastic exposure may intersect with key biological…
HHealth
Genetic mutation in some East Asians linked to aldehyde storm and increased liver disease risk
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Preclinical study reveals potential new treatment for severe liver fibrosis

  • January 14, 2026
Researchers at McMaster University are leading preclinical studies into a novel drug candidate developed by Espervita Therapeutics that has the potential to prevent and reverse liver fibrosis – a dangerous, disease-induced build-up of…
HHealth
Chronic illness death rates decline but pace of progress slows
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Study reveals bioactive compounds driving Borage’s diverse therapeutic benefits

  • January 7, 2026
For centuries, Borago officinalis – commonly known as Borage or the Starflower – has been a staple of…
HHealth
New insights reveal persistent genome structure during cell division
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Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

  • December 30, 2025
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
HHealth
Regular mammograms linked to longer survival in women over 80
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Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

  • December 27, 2025
Dec 26 2025 A new study published today in Science Translational Medicine by researchers at The University of…
HHealth
Compact bNIRS technology could become a diagnostic toolkit for dementia
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Research highlights a potential therapeutic strategy for vascular dementia

  • December 23, 2025
A possible new treatment for impaired brain blood flow and related dementias is on the horizon. Research by…
HHealth
Simple blood test maps hidden Alzheimer’s disease changes
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Simple blood test maps hidden Alzheimer’s disease changes

  • December 21, 2025
A large community study shows that Alzheimer’s-related brain changes are far more widespread with age than symptoms alone…
HHealth
SN101 iPSC-derived therapy relieves chronic pain and preserves joints
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SN101 iPSC-derived therapy relieves chronic pain and preserves joints

  • December 13, 2025
SereNeuro Therapeutics, a preclinical biotechnology company developing non-opioid pain therapies, unveiled new data today on a novel approach…
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