NIH awards $3.9 million grant to develop a non-opioid pain treatment
The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health (NIH), has awarded…
FINGERS-7B built to eradicate Alzheimer’s symptoms
Alzheimer’s disease is best addressed as early as possible, ideally before symptoms become apparent. To enable early, accurate…
Study finds three distinct patterns of cognitive decline in Alzheimer’s disease
Cognitive decline in Alzheimer’s disease differs substantially from one person to the next and is not well predicted…
Scientists identify STING switch driving inflammation in Alzheimer’s disease
The brain has its own immune system, which detects threats and mounts a defense. A growing body of…
Antisense oligonucleotides reverse rare neurodevelopmental disorder in preclinical models
Scientists at St. Jude Children’s Research Hospital have found they can reverse the effects of HNRNPH2-related neurodevelopmental disorder using…
EV-RNAs show promise for IBD diagnosis and treatment
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive…
New 3D organoid model advances pediatric glioma research and treatment
A three-dimensional experimental system has been developed to study the response to drugs in low-grade glioma, a tumor…
AI-powered chemistry accelerates discovery of selective cancer inhibitors
Recently, the Insilico team’s research entitled “An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potential and Sub-Family…
Highly potent opioid shows potential as therapy for pain and opioid use disorder
Researchers at the National Institutes of Health (NIH) have identified a novel, highly potent opioid that shows potential…
Palmatine improved fatty liver markers in a preclinical type 2 diabetes study
A new preclinical study suggests that palmatine may ease diabetes-linked fatty liver disease by targeting inflammation, oxidative stress,…
Scientists turn red blood cells into long-lasting drug and imaging carriers in mice
A new preclinical study shows that red blood cells can be tagged in vivo and used as long-lasting…
Oral semaglutide fails to slow early Alzheimer’s decline in two phase 3 trials
Despite hopes raised by earlier observational studies and biomarker shifts, The Lancet trials found that oral semaglutide did…