Study identifies protein essential for repairing damage after inflammation
Whenever there is a wound or infection, the body produces an inflammatory response. This is the body’s first…
Biliary epithelial cells found to actively prevent liver fibrosis development
Many liver diseases share a common characteristic: fibrosis, that is, the progressive accumulation of scarring in the liver…
Detailed images reveal DNA repair mechanism in cancer-related proteins
Scientists have captured the most detailed structural images to date of a specific type of protein’s DNA repair…
Cells under the spotlight reveal their inner secrets
All living things are made of cells, and the molecular machinery within them is imperative to survival. Different…
New blood filtering treatment safely extends pregnancy in severe preeclampsia
Cedars-Sinai Health Sciences University investigators have developed and successfully tested a new treatment for pregnant women with severe…
Intercellular heme transfer pathway sustains red blood cell production under stress
Scientists have long been puzzled by how maturing red blood cells manage to produce all the hemoglobin they…
Scientists identify STING switch driving inflammation in Alzheimer’s disease
The brain has its own immune system, which detects threats and mounts a defense. A growing body of…
Elevated Lp(a) levels associated with residual cardiovascular risk
New data analyzing more than 20,000 patients from three major NIH studies show that elevated Lipoprotein(a) [Lp(a)] is…
Exploiting a new weakness in ‘zombie-like’ cells to treat senescence-associated diseases
A new set of drugs exploit a recently-revealed weakness in ‘zombie-like’ – or senescent – cells that could lead to new treatments for cancer and age-associated diseases. The study from the…
L-arginine stabilizes protein droplets and prevents harmful fibril formation
Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer’s, these liquid-like droplets can…
Kenyan bat coronavirus uses human CEACAM6 to enter cells, raising spillover concerns
A newly characterized bat coronavirus can latch onto a human cell receptor found in the lung, giving scientists…
New human cell model replicates key mechanisms of neurodegenerative diseases
Researchers at LMU have developed a human cell model that replicates key mechanisms of neurodegenerative diseases – with…