Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice
A mouse study traces how immune cells activated in the intestine migrate to the dura and persist at…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
GLP-1 drugs appear psychiatrically safe, but one finding still raises questions
With millions of patients now taking GLP-1 drugs, researchers examined whether concerns about depression and suicidality are supported…
Semaglutide extended lifespan in older female mice, but that was not the only finding
A late-life experiment reveals how a widely used metabolic drug reshapes age-related physiology and molecular pathways, with effects…
Fleeting interactions between membrane sugar chains control cell division
Acting as an armor, a scaffold, and a communication platform in one, our cells’ plasma membrane lies at…
Study finds distinct patterns of innate immune activity in mental disorders
The immune system may also play a role in mental disorders. Scientists are investigating these links with brain…
A striking immune cell pattern emerges around a person’s 100th birthday
Rare immune cells found at strikingly high levels in people who live beyond 110 reveal an unusual pattern…
Study provides a more nuanced picture of biological mechanisms linked to autism
How does autism manifest in the brain? Researchers from the University of Southern Denmark and Odense University Hospital…
New study links chronic stress to immunotherapy resistance in tumors
Immunotherapy has transformed cancer treatment, yet many tumors remain stubbornly resistant to its effects. Among the most challenging are “cold tumors,” including…
New study identifies key pathway for delivering antisense cancer drugs
Antisense oligonucleotides (ASOs) have been proposed as a therapeutic approach to shut down the production of faulty proteins…
Ten-million-person study links semaglutide to lower COVID-19 mortality
After accounting for major health differences between semaglutide users and non-users, researchers identified a striking mortality association that…
Microbial metabolites could help improve functional cure rates for hepatitis B
Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure…