Rockefeller scientists engineer next-generation antibody to replace IVIG therapy
Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions. With origins…
Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
PTGES3 emerges as key regulator of androgen receptor in prostate cancer
A poorly characterized protein, historically thought to be a chaperone or enzyme, may actually be a key player…
Scientists uncover new obesity genes that reshape understanding of weight and disease risk
A global research team maps how rare and common gene variants jointly drive obesity and metabolic disease, offering…
Immune cell dysregulation and inflammatory mediators shape epilepsy risk
Background and objectives Emerging evidence implicates immune dysregulation and neuroinflammation in the pathogenesis of epilepsy, yet the causal…
Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally…
Research identifies biomarkers in blood to fine-tune breast cancer interventions
Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells…
Diabetes remission possible with GLP-1 drugs, Italian study confirms
Real-world data from over 14,000 Italian adults reveal that GLP-1 receptor agonists can induce remission in type 2…
How COVID mRNA vaccines may make cancer treatments more effective
A new study reveals that SARS-CoV-2 mRNA vaccines can amplify immune checkpoint therapy in lung and skin cancers…
New drug combination shows promise in treating colorectal cancer
Colorectal cancer is one of the most common tumors among people over the age of 50. Although it…
Researchers develop a novel approach to monitor CD8⁺ T cell activity over time
The ability of immune cells-particularly CD8+ T cells-to launch a rapid burst of proliferation inside tumors is key…
Blocking two enzymes weakens prostate tumors and boosts drug effectiveness
A major international study has uncovered a new vulnerability in prostate cancer cells that could help improve treatment…