Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer
Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden…
Comprehensive kinase atlas reveals new insights into cell signaling and disease
The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme’s…
Bowel cancer’s “Big Bang” moment reveals how the disease takes shape
Like the astronomical explosion that kickstarted the universe, bowel cancer has a “Big Bang” moment which determines how…
Large-scale foundation model reconstructs how cells interact within tissues
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation…
New molecule targets and destroys harmful RNA linked to cancer and aging
Within each cell, there is a constant struggle between life-sustaining molecules and molecules that could hasten its demise.…
Mutated RIG-I receptor causes kidney inflammation through Y-RNA activation
Researchers at the University Hospital Bonn (UKB) and the University of Bonn have discovered how a small, naturally…
Scientists capture a near-continuous molecular movie of ribosome formation
Ribosomes are the cell’s protein factories, which read the genetic code and assemble the proteins that every organism…
Unveiling the dual role of HIV integrase in viral replication
The rate of HIV infection continues to climb globally. Around 40 million people live with HIV-1, the most…
Researchers engineer a tool to dismantle cancer’s RNA-built growth hubs
In a city, coworking hubs bring people and ideas together. Inside cancer cells, similar hubs form-but instead of…
Scientists Create The Most Efficient Lifeform On Earth After Altering 101,000 Lines Of Genetic Code » TwistedSifter
Shutterstock Creating life is something that scientists have been able to do for a while now. In 2010,…
Cancer hijacks embryonic gene editors to fuel growth
Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks…
Research uncovers ASPL’s critical role in stress granule life cycle
Stress granules are droplet-like protein hubs that temporarily shield fragile RNA from cellular stresses such as toxins. VCP…