Maternal stress alters placental pathways affecting fetal brain development
About one in five U.S. women experience maternal mental health conditions, and chronic stress during pregnancy can contribute…
Researchers improve CRISPR technology for detecting HIV and other RNA viruses
Scientists have long used a powerful gene-editing tool called CRISPR to make precise changes to DNA. But a…
RNA modification enzyme FTO shows therapeutic promise in gastrointestinal cancers
A new review in Genes & Diseases highlights FTO, an enzyme involved in RNA modification, as a potentially…
Scientists identify the neuroblastoma cells that signal poor outcomes
Neuroblastoma is the most common solid tumor found outside of the brain in children, yet why some children…
Before the first bite: A missing gut protein may set the stage for peanut allergy
For most people, a peanut butter sandwich poses no threat. But for the roughly 1.6 million children in…
Simple urine test can accurately diagnose and track bladder cancer
A simple urine test devised by researchers at Stanford Medicine and the VA Palo Alto Health Care System…
The cellular landscape of druggable RNA-binding proteins
Gerstberger, S., Hafner, M. & Tuschl, T. A census of human RNA-binding proteins. Nat. Rev. Genet. 15, 829–845…
Advances in chemistry and delivery are taking oligonucleotide medicines beyond rare diseases
Decades of work on RNA targeting, chemical modification, and tissue-specific delivery are reshaping what programmable genetic medicines can…
Scientists map a giant parasite machine to fight tropical diseases
A study conducted between the University of Liège and Rockefeller University reveals, with near-atomic precision, the three-dimensional structure…
MIT researchers develop noninvasive way to spot aging zombie cells
As we age, some of the cells in our body enter a state of senescence, in which they…
Chronic interferon exposure drives immunosuppression in tumors
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most…
Microscopic peptide droplets reduce colorectal tumor growth in mice
Scientists from Nanyang Technological University, Singapore (NTU Singapore) have developed microscopic peptide droplets that deliver large amounts of…