Early genomic testing prevents years of inconclusive visits for pediatric patients
For many families, eight years of uncertainty meant repeated specialist visits, inconclusive genetic tests and the growing fear…
How the immune system may influence Alzheimer’s, Parkinson’s, and related diseases
A sweeping review shows how the brain’s immune defenses can both fight and fuel neurodegeneration, revealing why timing,…
Rat hepatitis E virus may be a hidden cause of hepatitis in humans
A growing body of evidence suggests that rat hepatitis E virus is spilling into humans more often than…
EV-RNAs show promise for IBD diagnosis and treatment
A research team led by Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, has published a comprehensive…
CIPHER-seq technology reveals how immune cells communicate during treatment
A new single-cell technology is giving scientists their clearest view yet of immune cell behavior-capturing not just genetic…
RNA barcoding maps neural connections with unprecedented resolution
By tagging neurons with molecular “barcodes,” researchers mapped connections among thousands of neurons in the mouse brain with…
Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
Metabolic pathways drive progression from pancreatic lesions to cancer
Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate.…
Study identifies a common hidden genetic cause of neurodevelopmental disorder in children
A major genetic study has uncovered a surprisingly common recessive cause of neurodevelopmental disorder, revealing how hidden changes…
Study revises the understanding of neutrophil dynamics during respiratory viral infection
Neutrophil infiltration is a hallmark of pulmonary inflammation during respiratory viral infections, yet the origin of these cells…
Targeting protein fragment may improve Huntington disease treatments
Treatments that target a fragment of the mutant protein that causes Huntington’s disease might be more effective than…
Study reveals new dual role of ezrin in osteosarcoma
Scientists at Georgetown University’s Lombardi Comprehensive Cancer Center have uncovered a new dual function for a well-known cancer-related…