Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
USC scientists target brain inflammation to prevent Alzheimer’s disease
An interdisciplinary team at the USC Center for Personalized Brain Health (CPBH) is targeting a family of enzymes…
Urine test may help identify autism risk in children
A simple urine test may help identify children at risk for autism sooner than current assessments – opening…
L-arginine stabilizes protein droplets and prevents harmful fibril formation
Protein droplets serve important biological functions within cells, but in neurodegenerative diseases like Alzheimer’s, these liquid-like droplets can…
New technique synthesizes non-natural amino acids for advanced peptide therapeutics
Ozempic has been making headlines for its remarkable success in treating obesity and diabetes. Yet it is just…
Early biomarkers predict infections after breast reconstruction surgery
In the U.S., one in eight women will get breast cancer in their lifetime, and about half of…
Polyamines reshape protein phosphorylation to guide key cellular fate decisions
Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an…
Targeting RNA with small molecules using state-of-the-art methods provides highly predictive affinities of riboswitch inhibitors
Harries, L. W. RNA biology provides new therapeutic targets for human disease. Front. Genet. 10, 205 (2019). CAS …
Scientists uncover how amino acids stabilize proteins in solution
For decades, amino acids have been added to medical formulations like insulin as stabilizers: these small molecules keep…