New study reveals nitric oxide’s widespread impact on genetics
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional…
Tumor splicing burden predicts treatment response in kidney cancer
Researchers at City of Hope® and TGen (part of City of Hope) have identified a significant correlation between…
Toxic RNA drives progressive heart damage in myotonic dystrophy
Myotonic dystrophy type 1 (DM1) is the most common cause of adult-onset muscular dystrophy, a genetic disorder that…
Study identifies a common hidden genetic cause of neurodevelopmental disorder in children
A major genetic study has uncovered a surprisingly common recessive cause of neurodevelopmental disorder, revealing how hidden changes…
FOXJ3 gene identified as the critical link between abnormal brain development and epilepsy
Researchers have discovered that mutations in the FOXJ3 gene act as a “master switch” failure, disrupting how the…
Polyamines reshape protein phosphorylation to guide key cellular fate decisions
Polyamines are small molecules naturally present in all cells and are critical in guiding cellular decisions, whereas an…
Gestational diabetes alters the placenta at the molecular level, study reveals
Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely…
Cancer hijacks embryonic gene editors to fuel growth
Cancer cells are known to reawaken embryonic genes to grow. A new study reveals the disease also hijacks…
Scientists uncover 53 genetic clues that shape math ability beyond IQ
An exciting new study reveals the hidden genetic architecture of quantitative ability, showing how brain wiring and signaling…