CellNavi predicts genes directing cellular transitions by learning a gene graph-enhanced cell state manifold
Input embeddings In CellNavi, we use single-cell raw count matrices as the only input. Specifically, the single-cell sequencing…
New tool enables and enhances protein investigations
A new tool greatly improves scientists’ ability to identify and study proteins that regulate gene activity in cells,…
Exercise combined with induced pluripotent stem cells enhances the Wnt1-Lmx1a loop in the midbrain of Parkinsonian mice to alleviate Parkinsonian symptoms
BACKGROUND The therapeutic potential of induced pluripotent stem cells (iPSCs) for Parkinson’s disease (PD) has been demonstrated. Exercise…
Transcriptomic insights and feeder-free culturing of porcine expanded potential stem cells from cloned embryos | Stem Cell Research & Therapy
Chemicals Unless otherwise indicated, all chemicals and reagents used in this study were purchased from Sigma-Aldrich (St. Louis,…
UniSA scientists awarded $2.9m to investigate genetic causes of deadly childhood brain cancer – News and events
22 September 2025
11-year-old Jess Bickley lost her battle with brain cancer in September 2023, five months…
Novel vitamin K analogs show promise for reversing neurodegenerative diseases
Neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Huntington’s disease are characterized by the progressive loss of neurons. The resulting…
Rare ABCA7 gene variants linked to Alzheimer’s risk
A new study from MIT neuroscientists reveals how rare variants of a gene called ABCA7 may contribute to…