Stem cell study identifies universal checkpoint controlling cell identity
A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint…
Nerve Damage Repaired Using Stem Cells — From Your Nose?
Two Northeastern University researchers want to make life better for people who’ve experienced serious physical trauma, the kind…
Key Driver of Long-Term Inflammatory Memory Identified
Newswise — One of the most puzzling aspects of common chronic inflammatory skin diseases such as psoriasis is…
New nanoparticle system boosts scalable production of therapeutic exosomes
Researchers from Xi’an Jiaotong-Liverpool University (XJTLU) in China have developed a streamlined process that makes it easier to…
CSF1R T567M mutation induces microglial dysfunction and synaptic impairment in patient iPSC-derived cerebral organoids of CSF1R-related disorder
Ayrignac X, Carra-Dalliere C, Codjia P, Mouzat K, Castelnovo G, Ellie E, et al. Evaluation of CSF1R-related adult…
Viagra ingredient improves symptoms in patients with Leigh syndrome
Sildenafil – an active ingredient also marketed under the name of Viagra – improves symptoms in patients with…
ATP delivery fixes dysfunctional dopamine packaging in Parkinson’s neurons
A new study shows how dysfunctional packaging of the neurotransmitter dopamine triggers toxic processes in neurons – and…
Scientists discover how muscle stem cells “flip a switch” to rebuild damaged muscle
Scientists at the University of California, Irvine’s School of Pharmacy & Pharmaceutical Sciences have discovered how muscle stem cells “flip…
Researchers reveal why SuperAgers retain youthful brain cell signatures into their 80s
A multiomic atlas of the aging human hippocampus uncovers how epigenetic regulation of neural stem cells and immature…
Alpha-Ketoglutarate Enhances Adipose-Derived Stem Cells Survival in Wound Healing by Hypoxia-Inducible Factor 1-Alpha-Mediated Redox Homeostasis and Glycogen-Dependent Bioenergetics
BACKGROUND Adipose-derived stem cells (ADSCs) hold significant therapeutic potential for regenerative medicine, particularly in wound healing, owing to…
Genetic mismatch identified as major risk factor in cord blood transplantation
A Japanese study of more than 7,400 patients has identified a genetic mismatch that sharply increases the risk…
Researchers find new way to halt leukemia stem cell growth
In a new study published in Nature Communications, a research team at the University of Oslo have examined…