New study uncovers bacterial route to testosterone production
Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease…
Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
New AI-based program is a shrink ray for proteins
A new AI-based program, dubbed Raygun, can suggest strategic cuts to a protein’s amino acid sequence to…
Chemists use programmable DNA to build precise protein crystals
For decades, scientists have largely relied on painstaking trial and error to coax proteins into crystalline forms. Crystallization…
Cells detect and silence invading transposons through abnormal RNA signals
Transposons, DNA sequences that can self-replicate and move (jump) throughout the genome, are widespread and can affect cell…
Scientists visualize a key cell protein regulating inflammatory disease pathways
University of Cincinnati structural biologists are the first in the world to visualize a key cell protein as part…
NIH awards $3.9 million grant to develop a non-opioid pain treatment
The National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health (NIH), has awarded…
Natural protein sequences represent only a fraction of what’s theoretically possible
The genetic code has given rise to the enormous diversity of proteins we see in nature—and rearranging…
The molecular mechanism that turns cool temps into nerve signals
When you reach into a bucket of ice, open your front door on a snowy day, or feel…
Scientists identify a molecular switch that controls water flow in the gut
Although constipation and diarrhea may seem like opposite problems, they both hinge on the same underlying issue: how…
Scientists capture real-time action of antiviral drugs on herpes
Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works. The…
Study shines light on how P2X4 receptor can be inhibited
A study carried out by the University of Bonn and the University Hospital Bonn throws light on how…