Catalysis chemists are joining forces for reproducibility
Key Insights Catalytic chemistry is vital to many economically valuable processes. Problems with reproducibility arise when important…
The covalent drug arsenal gets a new warhead
A new platform that adds bicyclobutanes to amines could be used to create covalent drugs that have…
Dichloromethane can act as an amide coupling reagent
In a chemistry version of whipping up a delicious dinner from pantry staples, researchers in Korea have…
Cross-coupling preserves stereochemistry of chiral carboxylic acids
Synthetic organic chemists love their cross-coupling reactions, in which they quickly construct a complex compound by connecting…
With Latent Terrain, crack open AI and explore neural synthesis in Max
“I’m not particularly interested in typing prompts to make stuff, I’m interested in breaking them and dissecting them,”…
‘Absurd’ radical reaction keeps stereochemistry intact
According to organic chemistry dogma, if you generate a radical on a chiral carbon, it’s going to…
Nickel foam reaction yields valuable aromatic amines
Turning nitroarenes into aromatic amines is a bread-and-butter organic chemistry reaction. And although there are many ways…
Phosphine unexpectedly mimics metals in a photocatalytic reaction
There’s a new entry in the growing body of evidence that main-group elements like phosphorous, which are…
Chemistry in Pictures: Glowing with pride
“It looks like a tiny solar system. But instead of planets, it’s a snapshot of my research journey…
Engineered enzyme makes amides from aldehydes
Amide bonds hold together proteins. They appear in a huge number of drug molecules. They’ve been “one…
Two unusual alkenes stretch the limits of molecular geometry
Some people just really enjoy pushing molecules out of their comfort zones. Neil Garg and his team at…
Trace additive cleans up Fischer-Tropsch synthesis
For almost a century, the industrial Fischer-Tropsch (FT) process has been used to convert syngas—a blend of carbon…