Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Cryo-EM provides real-time glimpse of cellular machinery reading DNA inside living organisms
All living things have a fleet of tiny copy machines that turn instructions from DNA into RNA, the…
Astrocytes found to directly regulate memory consolidation during sleep
Research has shown that a good night’s sleep has many benefits, including memory consolidation. How sleep enables the…
New review highlights FOXA2’s role in glucose regulation pathways
A newly published review highlights the pivotal role of FOXA2, a key transcription factor, in coordinating pancreatic development,…
Microbial metabolites could help improve functional cure rates for hepatitis B
Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure…
Researchers identify key barrier preventing self repair of heart cells
Specialized cells in our body make biological tradeoffs to do certain jobs. To support large and hardworking hearts…
Scientists discover master molecular switch for ginseng saponin production
Sanchi ginseng (Panax notoginseng) is a cornerstone of traditional Chinese medicine, prized for its saponins-bioactive compounds with anti-inflammatory,…
New portable strip test accurately detects mosquito-borne viruses
A research team has developed a multisite bridging-mediated lateral flow immunoassay (mbLFIA) that enables highly sensitive, portable detection…
Targeting CMPK2-intervened redox metabolism to mitigate hepatic ischemia-reperfusion injury
HIRI is a major clinical challenge that occurs when blood supply to the liver is temporarily interrupted and…
Study reveals distinct roles of oxygen-sensing proteins in skeletal muscles
Skeletal muscles-responsible for movement, joint stabilization, and postural support-are highly metabolically active and heavily reliant on oxygen during…
Stem cell study uncovers molecular pathway for enamel regeneration
Tooth enamel is the hardest substance in the human body, yet once damaged, it cannot regenerate naturally. To…
Study identifies key fibrotic cells driving hypertrophic scars
Hypertrophic scars (HS) are abnormal outcomes of wound healing, marked by excessive extracellular matrix (ECM) deposition and impaired…