Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…
MHC class II marks stronger immune response and longer survival in ovarian cancer
A new study sheds light on why some patients with the most aggressive form of ovarian cancer respond…
Nervous system actively promotes pre-cancerous pancreatic lesions
Pancreatic cancer has a lot of nerve. Notoriously tricky to detect, the disease also often resists traditional therapy.…
Tumor-targeted chimeric drug increases efficacy and limits side effects
Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more…
Cholesterol transporter ABCA1 boosts macrophage-driven cancer immunity
In recent years, cancer researchers have made major breakthroughs by using the body’s immune system to fight cancer.…
RNA micelles enable targeted chemotherapy without immune toxicity
A new study in mice hints at the potential to use tiny particles made with RNA molecules to…
Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help…
Oral cancer pain and opioid tolerance share a common EGFR mechanism
Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and makes…
New nanomaterial kills cancer cells via oxidative stress
Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside…
Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps…
Cancer’s double-edged sword of growth and DNA damage
New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers…
Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments
Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and…