Tumor microenvironment drives resistance to ferroptosis in pancreatic cancer
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can…
Healthy thymus gland linked to longer life and immune stability
People with a healthy thymus gland live longer and are less likely to fall ill. In addition, immunotherapies…
Can AI chatbots help brain tumor patients understand their care?
AI tools could transform how brain tumor patients access and understand critical care information, but without careful oversight,…
New guidance aims to standardize tumor mutational burden in cancer
Immune checkpoint inhibitors have transformed cancer care, yet only a minority of patients respond to monotherapy, and immune-related…
Blood pressure drug boosts effectiveness of cancer therapy
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP,…
Systematic review identifies stress-induced biological triggers in oncology
Stress is a constant companion in the oncologist’s office. It appears at the time of diagnosis, increases with…
New nanoparticle therapy overcomes T cell exhaustion in solid tumors
Engineers at the University of Pennsylvania have developed a new type of lipid nanoparticle (LNP) that could one…
Blocking fructose metabolism may improve brain tumor immunotherapy response
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
SonoPIN technology boosts intracellular delivery of large cancer drugs
Engineers at Duke University have demonstrated a technique that uses microbubbles and ultrasound to help relatively large cancer…
Decoding the neighborhood dynamics of Childhood Brain Cancer
New research published in Nature finds that tumor cells within supratentorial ependymomas (SE) – an aggressive childhood brain…
DNA origami vaccine platform shows promise against multiple infectious viruses
The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical…