Chronic interferon exposure drives immunosuppression in tumors
Cancer biology and, in turn, cancer treatment have come a long way in the last few decades. Most…
Aging brain actively shapes biology and progression of tumors
Brain tumors develop within an organ that changes substantially with age. A new review in Ageing and Cancer…
Inhibitory neurons act as a brake on brain tumor growth
Brain tumors do not grow in isolation. They develop within the highly active environment of the brain, where…
Study shows how cancer can act as a systemic disease
In their quest to understand how cancers take root, grow and spread, scientists have for the past half-century…
Probiotics for mental health? A new review finds promising signals and major gaps
Researchers map the probiotic strains and gut-brain pathways being investigated across anxiety, depression, bipolar disorder, and schizophrenia, revealing…
New funding backs pioneering research to make brain cancer treatment more effective
Adelaide researchers are challenging decades-old assumptions about brain cancer treatment in a bid to make radiation therapy more…
Study reveals why diffuse midline glioma develops in brain midline regions
Scientists at St. Jude Children’s Research Hospital have shown that specific brain cells respond differently to the H3.3…
Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
A striking immune cell pattern emerges around a person’s 100th birthday
Rare immune cells found at strikingly high levels in people who live beyond 110 reveal an unusual pattern…
New study links chronic stress to immunotherapy resistance in tumors
Immunotherapy has transformed cancer treatment, yet many tumors remain stubbornly resistant to its effects. Among the most challenging are “cold tumors,” including…
Single-cell profiling of HDAC inhibitor-induced EBV lytic heterogeneity defines abortive and refractory states in B lymphoblasts
Epstein-Barr virus (EBV) is associated with multiple malignancies including Burkitt lymphoma (BL), Hodgkin’s lymphomas, nasopharyngeal carcinomas (NPC), and…
New study identifies key pathway for delivering antisense cancer drugs
Antisense oligonucleotides (ASOs) have been proposed as a therapeutic approach to shut down the production of faulty proteins…