Cholesterol transporter ABCA1 boosts macrophage-driven cancer immunity
In recent years, cancer researchers have made major breakthroughs by using the body’s immune system to fight cancer.…
RNA micelles enable targeted chemotherapy without immune toxicity
A new study in mice hints at the potential to use tiny particles made with RNA molecules to…
Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help…
Oral cancer pain and opioid tolerance share a common EGFR mechanism
Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and makes…
New nanomaterial kills cancer cells via oxidative stress
Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside…
Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps…
Cancer’s double-edged sword of growth and DNA damage
New study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers…
Web-based cytometry atlas reveals immune signatures across pancreatic cancer treatments
Oncologists have achieved some immune system responses in patients with pancreatic cancers using various combinations of vaccines and…
Investigational cancer vaccine shows early promise for cancer prevention in Lynch syndrome
The investigational cancer vaccine, NOUS-209, was found to safely stimulate the immune system to target precancerous and cancerous…
AI identifies promising CDK9 inhibitors for cancer treatment
A new and important discovery comes from the field of oncological research thanks to the joint work of…
CTDNEP1 identified as potential tumor suppressor in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer and begins in the cells lining…
Bacterial metabolite enhances immune checkpoint therapy against lung cancer
UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response…