Polymer-based immunotherapies enhance tumor targeting and immune activation
Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less…
Restoring ADAR2 enzyme reduces metastatic spread in osteosarcoma
Osteosarcoma is the most common primary bone cancer in children, adolescents, and young adults. Although chemotherapy and surgery…
New mRNA vaccine strategy dramatically amplifies cancer-fighting T cells
Engineers from the University of Houston, MIT and Harvard have developed a new mRNA-based strategy that dramatically amplifies…
Molecular profiling initiative seeks to uncover late breast cancer recurrence mysteries
The ECOG-ACRIN Cancer Research Group (ECOG-ACRIN), in collaboration with the SWOG Cancer Research Network (SWOG), has launched a…
Cancer Mystery Solved: Scientists Discover How Melanoma Becomes “Immortal”
Melanoma cells appear to rely on a hidden genetic partnership to keep dividing far beyond their normal lifespan.…
Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity
Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset…
Study challenges assumptions about testosterone’s role in brain cancer
Scientists have long suspected that androgens, male sex hormones like testosterone, may help tumors grow because the hormones…
Researchers uncover how bacterial toxin damages colon lining cells to trigger cancer
Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor…
Multi-center research initiative aims to improve glioblastoma patient outcomes
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center are part of a new multi-institution research effort aimed at improving…
New nanoparticles disable drug resistance to achieve complete tumor elimination
Cancer cells frequently develop the ability to expel anticancer drugs before they can work — a phenomenon called…
Chromosome abnormalities may help cancer cells resist treatment and spread
A new study led by NYU Langone Health researchers found that cancer cells are better able to resist…
A new combined therapy to boost the immune system against cancer
Cancer immunotherapy is built on a simple but powerful idea: the immune system can recognize and destroy cancer…