{"id":112948,"date":"2025-11-03T11:42:09","date_gmt":"2025-11-03T11:42:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/112948\/"},"modified":"2025-11-03T11:42:09","modified_gmt":"2025-11-03T11:42:09","slug":"diffusely-metastatic-glioblastoma-with-fgfr3tacc3-fusion-cell-free-dna-fragmentation-analyses-and-molecular-characterization-of-matched-primary-and-metastatic-tumor-sites-acta-neuropathologica-co","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/112948\/","title":{"rendered":"Diffusely metastatic glioblastoma with FGFR3::TACC3 fusion: cell-free DNA fragmentation analyses and molecular characterization of matched primary and metastatic tumor sites | Acta Neuropathologica Communications"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Achi J, Achi XW, Veintimilla P, Cueva J (2023) Unusual extraneural metastasis of glioblastoma. Surg Neurol Int 14:218. <a href=\"https:\/\/doi.org\/10.25259\/sni_191_2023\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.25259\/sni_191_2023\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.25259\/sni_191_2023<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.25259\/sni_191_2023\" data-track-item_id=\"10.25259\/sni_191_2023\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.25259%2Fsni_191_2023\" aria-label=\"Article reference 1\" data-doi=\"10.25259\/sni_191_2023\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37404487\" aria-label=\"PubMed reference 1\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10316183\" aria-label=\"PubMed Central reference 1\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 1\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Unusual%20extraneural%20metastasis%20of%20glioblastoma&amp;journal=Surg%20Neurol%20Int&amp;doi=10.25259%2Fsni_191_2023&amp;volume=14&amp;publication_year=2023&amp;author=Achi%2CJ&amp;author=Achi%2CXW&amp;author=Veintimilla%2CP&amp;author=Cueva%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR2\">Anghileri E, Castiglione M, Nunziata R, Boffano C, Nazzi V, Acerbi F, Finocchiaro G, Eoli M (2016) Extraneural metastases in glioblastoma patients: two cases with YKL-40-positive glioblastomas and a meta-analysis of the literature. Neurosurg Rev 39:37\u201345<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s10143-015-0656-9\" data-track-item_id=\"10.1007\/s10143-015-0656-9\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s10143-015-0656-9\" aria-label=\"Article reference 2\" data-doi=\"10.1007\/s10143-015-0656-9\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26212701\" aria-label=\"PubMed reference 2\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 2\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extraneural%20metastases%20in%20glioblastoma%20patients%3A%20two%20cases%20with%20YKL-40-positive%20glioblastomas%20and%20a%20meta-analysis%20of%20the%20literature&amp;journal=Neurosurg%20Rev&amp;doi=10.1007%2Fs10143-015-0656-9&amp;volume=39&amp;pages=37-45&amp;publication_year=2016&amp;author=Anghileri%2CE&amp;author=Castiglione%2CM&amp;author=Nunziata%2CR&amp;author=Boffano%2CC&amp;author=Nazzi%2CV&amp;author=Acerbi%2CF&amp;author=Finocchiaro%2CG&amp;author=Eoli%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR3\">Anzil AP (1970) Glioblastoma multiforme with extracranial metastases in the absence of previous craniotomy: case report. J Neurosurg 33:88\u201394. <a href=\"https:\/\/doi.org\/10.3171\/jns.1970.33.1.0088\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.3171\/jns.1970.33.1.0088\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.3171\/jns.1970.33.1.0088<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3171\/jns.1970.33.1.0088\" data-track-item_id=\"10.3171\/jns.1970.33.1.0088\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3171%2Fjns.1970.33.1.0088\" aria-label=\"Article reference 3\" data-doi=\"10.3171\/jns.1970.33.1.0088\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaE3c3ivFGntA%3D%3D\" aria-label=\"CAS reference 3\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=4316740\" aria-label=\"PubMed reference 3\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 3\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Glioblastoma%20multiforme%20with%20extracranial%20metastases%20in%20the%20absence%20of%20previous%20craniotomy%3A%20case%20report&amp;journal=J%20Neurosurg&amp;doi=10.3171%2Fjns.1970.33.1.0088&amp;volume=33&amp;pages=88-94&amp;publication_year=1970&amp;author=Anzil%2CAP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR4\">Ben Nsir A, Thai QA, Kassar AZ, Ben Said I, Jemel H (2015) Primary cerebellar Gliosarcoma with extracranial metastases: an orphan differential diagnosis. World Neurosurg 84:2076. <a href=\"https:\/\/doi.org\/10.1016\/j.wneu.2015.07.049\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/j.wneu.2015.07.049\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/j.wneu.2015.07.049<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.wneu.2015.07.049\" data-track-item_id=\"10.1016\/j.wneu.2015.07.049\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.wneu.2015.07.049\" aria-label=\"Article reference 4\" data-doi=\"10.1016\/j.wneu.2015.07.049\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 4\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Primary%20cerebellar%20Gliosarcoma%20with%20extracranial%20metastases%3A%20an%20orphan%20differential%20diagnosis&amp;journal=World%20Neurosurg&amp;doi=10.1016%2Fj.wneu.2015.07.049&amp;volume=84&amp;publication_year=2015&amp;author=Ben%20Nsir%2CA&amp;author=Thai%2CQA&amp;author=Kassar%2CAZ&amp;author=Ben%20Said%2CI&amp;author=Jemel%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR5\">Briones-Claudett KH, Briones-Claudett MH, Villacr\u00e9s Garcia F, Ortega Almeida C, Escudero-Requena A, Ben\u00edtezSol\u00eds J, Briones Zamora KH, Briones M\u00e1rquez DC, Grunauer M (2020) Early pulmonary metastasis after a surgical resection of glioblastoma multiforme. A case report. Am J Case Rep 21:e922976. <a href=\"https:\/\/doi.org\/10.12659\/ajcr.922976\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.12659\/ajcr.922976\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.12659\/ajcr.922976<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.12659\/ajcr.922976\" data-track-item_id=\"10.12659\/ajcr.922976\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.12659%2Fajcr.922976\" aria-label=\"Article reference 5\" data-doi=\"10.12659\/ajcr.922976\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32794473\" aria-label=\"PubMed reference 5\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7414824\" aria-label=\"PubMed Central reference 5\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 5\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Early%20pulmonary%20metastasis%20after%20a%20surgical%20resection%20of%20glioblastoma%20multiforme.%20A%20case%20report&amp;journal=Am%20J%20Case%20Rep&amp;doi=10.12659%2Fajcr.922976&amp;volume=21&amp;publication_year=2020&amp;author=Briones-Claudett%2CKH&amp;author=Briones-Claudett%2CMH&amp;author=Villacr%C3%A9s%20Garcia%2CF&amp;author=Ortega%20Almeida%2CC&amp;author=Escudero-Requena%2CA&amp;author=Ben%C3%ADtezSol%C3%ADs%2CJ&amp;author=Briones%20Zamora%2CKH&amp;author=Briones%20M%C3%A1rquez%2CDC&amp;author=Grunauer%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR6\">Choi MG, Lee JH, Lee MS, Suh SJ, Lee YS, Kang DG (2020) Primary gliosarcoma with extracranial metastasis. Brain Tumor Res Treat 8:53\u201356. <a href=\"https:\/\/doi.org\/10.14791\/btrt.2020.8.e9\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.14791\/btrt.2020.8.e9\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.14791\/btrt.2020.8.e9<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.14791\/btrt.2020.8.e9\" data-track-item_id=\"10.14791\/btrt.2020.8.e9\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.14791%2Fbtrt.2020.8.e9\" aria-label=\"Article reference 6\" data-doi=\"10.14791\/btrt.2020.8.e9\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32390354\" aria-label=\"PubMed reference 6\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7221469\" aria-label=\"PubMed Central reference 6\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 6\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Primary%20gliosarcoma%20with%20extracranial%20metastasis&amp;journal=Brain%20Tumor%20Res%20Treat&amp;doi=10.14791%2Fbtrt.2020.8.e9&amp;volume=8&amp;pages=53-56&amp;publication_year=2020&amp;author=Choi%2CMG&amp;author=Lee%2CJH&amp;author=Lee%2CMS&amp;author=Suh%2CSJ&amp;author=Lee%2CYS&amp;author=Kang%2CDG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR7\">Chung YH, Wong SL, Huang HY (1999) Endobronchial metastasis of glioblastoma multiforme diagnosed by fiberoptic bronchoscopic biopsy. J Formos Med Assoc 98:133\u2013135<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaK1M7otleguw%3D%3D\" aria-label=\"CAS reference 7\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=10083770\" aria-label=\"PubMed reference 7\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 7\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Endobronchial%20metastasis%20of%20glioblastoma%20multiforme%20diagnosed%20by%20fiberoptic%20bronchoscopic%20biopsy&amp;journal=J%20Formos%20Med%20Assoc&amp;volume=98&amp;pages=133-135&amp;publication_year=1999&amp;author=Chung%2CYH&amp;author=Wong%2CSL&amp;author=Huang%2CHY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR8\">Cunha M, Maldaun MVC (2019) Metastasis from glioblastoma multiforme: a meta-analysis. Rev Assoc Med Bras 65:424\u2013433. <a href=\"https:\/\/doi.org\/10.1590\/1806-9282.65.3.424\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1590\/1806-9282.65.3.424\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1590\/1806-9282.65.3.424<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1590\/1806-9282.65.3.424\" data-track-item_id=\"10.1590\/1806-9282.65.3.424\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1590%2F1806-9282.65.3.424\" aria-label=\"Article reference 8\" data-doi=\"10.1590\/1806-9282.65.3.424\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30994843\" aria-label=\"PubMed reference 8\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 8\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Metastasis%20from%20glioblastoma%20multiforme%3A%20a%20meta-analysis&amp;journal=Rev%20Assoc%20Med%20Bras&amp;doi=10.1590%2F1806-9282.65.3.424&amp;volume=65&amp;pages=424-433&amp;publication_year=2019&amp;author=Cunha%2CM&amp;author=Maldaun%2CMVC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR9\">Didelot A, Taillandier L, Grignon Y, Vespignani H, Beauchesne P (2006) Concomitant bone marrow metastasis of a glioblastoma multiforme revealed at the diagnosis. Acta Neurochir (Wien) 148:997\u20131000. <a href=\"https:\/\/doi.org\/10.1007\/s00701-006-0854-x\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1007\/s00701-006-0854-x\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1007\/s00701-006-0854-x<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s00701-006-0854-x\" data-track-item_id=\"10.1007\/s00701-006-0854-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s00701-006-0854-x\" aria-label=\"Article reference 9\" data-doi=\"10.1007\/s00701-006-0854-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DC%2BD28rislOgsA%3D%3D\" aria-label=\"CAS reference 9\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16932995\" aria-label=\"PubMed reference 9\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 9\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Concomitant%20bone%20marrow%20metastasis%20of%20a%20glioblastoma%20multiforme%20revealed%20at%20the%20diagnosis&amp;journal=Acta%20Neurochir%20%28Wien%29&amp;doi=10.1007%2Fs00701-006-0854-x&amp;volume=148&amp;pages=997-1000&amp;publication_year=2006&amp;author=Didelot%2CA&amp;author=Taillandier%2CL&amp;author=Grignon%2CY&amp;author=Vespignani%2CH&amp;author=Beauchesne%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR10\">Fabregat A, Sidiropoulos K, Viteri G, Forner O, Marin-Garcia P, Arnau V, D\u2019Eustachio P, Stein L, Hermjakob H (2017) Reactome pathway analysis: a high-performance in-memory approach. BMC Bioinform 18:142. <a href=\"https:\/\/doi.org\/10.1186\/s12859-017-1559-2\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1186\/s12859-017-1559-2\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1186\/s12859-017-1559-2<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12859-017-1559-2\" data-track-item_id=\"10.1186\/s12859-017-1559-2\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12859-017-1559-2\" aria-label=\"Article reference 10\" data-doi=\"10.1186\/s12859-017-1559-2\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXjvVWitb8%3D\" aria-label=\"CAS reference 10\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 10\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Reactome%20pathway%20analysis%3A%20a%20high-performance%20in-memory%20approach&amp;journal=BMC%20Bioinform&amp;doi=10.1186%2Fs12859-017-1559-2&amp;volume=18&amp;publication_year=2017&amp;author=Fabregat%2CA&amp;author=Sidiropoulos%2CK&amp;author=Viteri%2CG&amp;author=Forner%2CO&amp;author=Marin-Garcia%2CP&amp;author=Arnau%2CV&amp;author=D%E2%80%99Eustachio%2CP&amp;author=Stein%2CL&amp;author=Hermjakob%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR11\">Fabregat A, Sidiropoulos K, Viteri G, Marin-Garcia P, Ping P, Stein L, D\u2019Eustachio P, Hermjakob H (2018) Reactome diagram viewer: data structures and strategies to boost performance. Bioinformatics 34:1208\u20131214. <a href=\"https:\/\/doi.org\/10.1093\/bioinformatics\/btx752\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/bioinformatics\/btx752\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/bioinformatics\/btx752<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btx752\" data-track-item_id=\"10.1093\/bioinformatics\/btx752\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtx752\" aria-label=\"Article reference 11\" data-doi=\"10.1093\/bioinformatics\/btx752\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXitlGku73P\" aria-label=\"CAS reference 11\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29186351\" aria-label=\"PubMed reference 11\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 11\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Reactome%20diagram%20viewer%3A%20data%20structures%20and%20strategies%20to%20boost%20performance&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtx752&amp;volume=34&amp;pages=1208-1214&amp;publication_year=2018&amp;author=Fabregat%2CA&amp;author=Sidiropoulos%2CK&amp;author=Viteri%2CG&amp;author=Marin-Garcia%2CP&amp;author=Ping%2CP&amp;author=Stein%2CL&amp;author=D%E2%80%99Eustachio%2CP&amp;author=Hermjakob%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR12\">Frank S, Kuhn SA, Brodhun M, Mueller U, Romeike B, Kosmehl H, Regenbrecht CR, Ewald C, Reichart R, Kalff R (2009) Metastatic glioblastoma cells use common pathways via blood and lymphatic vessels. Neurol Neurochir Pol 43:183\u2013190<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=19484696\" aria-label=\"PubMed reference 12\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 12\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Metastatic%20glioblastoma%20cells%20use%20common%20pathways%20via%20blood%20and%20lymphatic%20vessels&amp;journal=Neurol%20Neurochir%20Pol&amp;volume=43&amp;pages=183-190&amp;publication_year=2009&amp;author=Frank%2CS&amp;author=Kuhn%2CSA&amp;author=Brodhun%2CM&amp;author=Mueller%2CU&amp;author=Romeike%2CB&amp;author=Kosmehl%2CH&amp;author=Regenbrecht%2CCR&amp;author=Ewald%2CC&amp;author=Reichart%2CR&amp;author=Kalff%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR13\">Frappaz D, Mornex F, Saint-Pierre G, Ranchere-Vince D, Jouvet A, Chassagne-Clement C, Thiesse P, Mere P, Deruty R (1999) Bone metastasis of glioblastoma multiforme confirmed by fine needle biopsy. Acta Neurochir (Wien) 141:551\u2013552. <a href=\"https:\/\/doi.org\/10.1007\/s007010050342\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1007\/s007010050342\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1007\/s007010050342<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s007010050342\" data-track-item_id=\"10.1007\/s007010050342\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s007010050342\" aria-label=\"Article reference 13\" data-doi=\"10.1007\/s007010050342\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaK1MzitVGitg%3D%3D\" aria-label=\"CAS reference 13\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=10392217\" aria-label=\"PubMed reference 13\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 13\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Bone%20metastasis%20of%20glioblastoma%20multiforme%20confirmed%20by%20fine%20needle%20biopsy&amp;journal=Acta%20Neurochir%20%28Wien%29&amp;doi=10.1007%2Fs007010050342&amp;volume=141&amp;pages=551-552&amp;publication_year=1999&amp;author=Frappaz%2CD&amp;author=Mornex%2CF&amp;author=Saint-Pierre%2CG&amp;author=Ranchere-Vince%2CD&amp;author=Jouvet%2CA&amp;author=Chassagne-Clement%2CC&amp;author=Thiesse%2CP&amp;author=Mere%2CP&amp;author=Deruty%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR14\">Georgescu MM, Olar A (2020) Genetic and histologic spatiotemporal evolution of recurrent, multifocal, multicentric and metastatic glioblastoma. Acta Neuropathol Commun 8:10. <a href=\"https:\/\/doi.org\/10.1186\/s40478-020-0889-x\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1186\/s40478-020-0889-x\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1186\/s40478-020-0889-x<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s40478-020-0889-x\" data-track-item_id=\"10.1186\/s40478-020-0889-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s40478-020-0889-x\" aria-label=\"Article reference 14\" data-doi=\"10.1186\/s40478-020-0889-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXltFeltLY%3D\" aria-label=\"CAS reference 14\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32014051\" aria-label=\"PubMed reference 14\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6998196\" aria-label=\"PubMed Central reference 14\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 14\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genetic%20and%20histologic%20spatiotemporal%20evolution%20of%20recurrent%2C%20multifocal%2C%20multicentric%20and%20metastatic%20glioblastoma&amp;journal=Acta%20Neuropathol%20Commun&amp;doi=10.1186%2Fs40478-020-0889-x&amp;volume=8&amp;publication_year=2020&amp;author=Georgescu%2CMM&amp;author=Olar%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR15\">Greif J, Horovitz M, Marmor S (1998) Pleuropulmonary metastasis from an intracranial glioblastoma. Lung Cancer 20:135\u2013137. <a href=\"https:\/\/doi.org\/10.1016\/s0169-5002(98)00029-4\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/s0169-5002(98)00029-4\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/s0169-5002(98)00029-4<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/s0169-5002(98)00029-4\" data-track-item_id=\"10.1016\/s0169-5002(98)00029-4\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fs0169-5002%2898%2900029-4\" aria-label=\"Article reference 15\" data-doi=\"10.1016\/s0169-5002(98)00029-4\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaK1cznslCisw%3D%3D\" aria-label=\"CAS reference 15\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=9711532\" aria-label=\"PubMed reference 15\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 15\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Pleuropulmonary%20metastasis%20from%20an%20intracranial%20glioblastoma&amp;journal=Lung%20Cancer&amp;doi=10.1016%2Fs0169-5002%2898%2900029-4&amp;volume=20&amp;pages=135-137&amp;publication_year=1998&amp;author=Greif%2CJ&amp;author=Horovitz%2CM&amp;author=Marmor%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR16\">Hoffman HA, Li CH, Everson RG, Strunck JL, Yong WH, Lu DC (2017) Primary lung metastasis of glioblastoma multiforme with epidural spinal metastasis: case report. J Clin Neurosci 41:97\u201399. <a href=\"https:\/\/doi.org\/10.1016\/j.jocn.2017.03.033\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/j.jocn.2017.03.033\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/j.jocn.2017.03.033<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.jocn.2017.03.033\" data-track-item_id=\"10.1016\/j.jocn.2017.03.033\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.jocn.2017.03.033\" aria-label=\"Article reference 16\" data-doi=\"10.1016\/j.jocn.2017.03.033\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=28343918\" aria-label=\"PubMed reference 16\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 16\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Primary%20lung%20metastasis%20of%20glioblastoma%20multiforme%20with%20epidural%20spinal%20metastasis%3A%20case%20report&amp;journal=J%20Clin%20Neurosci&amp;doi=10.1016%2Fj.jocn.2017.03.033&amp;volume=41&amp;pages=97-99&amp;publication_year=2017&amp;author=Hoffman%2CHA&amp;author=Li%2CCH&amp;author=Everson%2CRG&amp;author=Strunck%2CJL&amp;author=Yong%2CWH&amp;author=Lu%2CDC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR17\">Hu X, Deng Q, Ma L, Li Q, Chen Y, Liao Y, Zhou F, Zhang C, Shao L, Feng J et al (2020) Meningeal lymphatic vessels regulate brain tumor drainage and immunity. Cell Res 30:229\u2013243. <a href=\"https:\/\/doi.org\/10.1038\/s41422-020-0287-8\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1038\/s41422-020-0287-8\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1038\/s41422-020-0287-8<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41422-020-0287-8\" data-track-item_id=\"10.1038\/s41422-020-0287-8\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41422-020-0287-8\" aria-label=\"Article reference 17\" data-doi=\"10.1038\/s41422-020-0287-8\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXkt1ehu7Y%3D\" aria-label=\"CAS reference 17\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32094452\" aria-label=\"PubMed reference 17\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7054407\" aria-label=\"PubMed Central reference 17\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 17\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Meningeal%20lymphatic%20vessels%20regulate%20brain%20tumor%20drainage%20and%20immunity&amp;journal=Cell%20Res&amp;doi=10.1038%2Fs41422-020-0287-8&amp;volume=30&amp;pages=229-243&amp;publication_year=2020&amp;author=Hu%2CX&amp;author=Deng%2CQ&amp;author=Ma%2CL&amp;author=Li%2CQ&amp;author=Chen%2CY&amp;author=Liao%2CY&amp;author=Zhou%2CF&amp;author=Zhang%2CC&amp;author=Shao%2CL&amp;author=Feng%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR18\">Hulbanni S, Goodman PA (1976) Glioblastoma multiforme with extraneural metastases in the absence of previous surgery. Cancer 37:1577\u20131583. <a href=\"https:\/\/doi.org\/10.1002\/1097-0142(197603)37:3%3c1577::aid-cncr2820370348%3e3.0.co;2-0\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1002\/1097-0142(197603)37:3%3c1577::aid-cncr2820370348%3e3.0.co;2-0\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1002\/1097-0142(197603)37:3%3c1577::aid-cncr2820370348%3e3.0.co;2-0<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/1097-0142(197603)37:3&lt;1577::aid-cncr2820370348&gt;3.0.co;2-0\" data-track-item_id=\"10.1002\/1097-0142(197603)37:3&lt;1577::aid-cncr2820370348&gt;3.0.co;2-0\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2F1097-0142%28197603%2937%3A3%3C1577%3A%3Aaid-cncr2820370348%3E3.0.co%3B2-0\" aria-label=\"Article reference 18\" data-doi=\"10.1002\/1097-0142(197603)37:3&lt;1577::aid-cncr2820370348&gt;3.0.co;2-0\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaE287mt12itQ%3D%3D\" aria-label=\"CAS reference 18\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=177171\" aria-label=\"PubMed reference 18\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 18\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Glioblastoma%20multiforme%20with%20extraneural%20metastases%20in%20the%20absence%20of%20previous%20surgery&amp;journal=Cancer&amp;doi=10.1002%2F1097-0142%28197603%2937%3A3%3C1577%3A%3Aaid-cncr2820370348%3E3.0.co%3B2-0&amp;volume=37&amp;pages=1577-1583&amp;publication_year=1976&amp;author=Hulbanni%2CS&amp;author=Goodman%2CPA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR19\">Johnson RP, Guillan RA (1974) Glioblastoma multiforme with remote extracranial metastases. J Kans Med Soc 75:169\u2013172<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaE2c7ls1yjsg%3D%3D\" aria-label=\"CAS reference 19\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=4363614\" aria-label=\"PubMed reference 19\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 19\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Glioblastoma%20multiforme%20with%20remote%20extracranial%20metastases&amp;journal=J%20Kans%20Med%20Soc&amp;volume=75&amp;pages=169-172&amp;publication_year=1974&amp;author=Johnson%2CRP&amp;author=Guillan%2CRA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR20\">Kandemir NO, Bahadir B, G\u00fcl S, Karadayi N, Ozdamar SO (2009) Glioblastoma with primitive neuroectodermal tumor-like features: case report. Turk Neurosurg 19:260\u2013264<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=19621291\" aria-label=\"PubMed reference 20\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 20\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Glioblastoma%20with%20primitive%20neuroectodermal%20tumor-like%20features%3A%20case%20report&amp;journal=Turk%20Neurosurg&amp;volume=19&amp;pages=260-264&amp;publication_year=2009&amp;author=Kandemir%2CNO&amp;author=Bahadir%2CB&amp;author=G%C3%BCl%2CS&amp;author=Karadayi%2CN&amp;author=Ozdamar%2CSO\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR21\">Khattab MH, Marciscano AE, Lo SS, Lim M, Laterra JJ, Kleinberg LR, Redmond KJ (2015) Antiangiogenic therapies and extracranial metastasis in glioblastoma: a case report and review of the literature. Case Rep Oncol Med 2015:431819. <a href=\"https:\/\/doi.org\/10.1155\/2015\/431819\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1155\/2015\/431819\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1155\/2015\/431819<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1155\/2015\/431819\" data-track-item_id=\"10.1155\/2015\/431819\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1155%2F2015%2F431819\" aria-label=\"Article reference 21\" data-doi=\"10.1155\/2015\/431819\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26199775\" aria-label=\"PubMed reference 21\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4493308\" aria-label=\"PubMed Central reference 21\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 21\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Antiangiogenic%20therapies%20and%20extracranial%20metastasis%20in%20glioblastoma%3A%20a%20case%20report%20and%20review%20of%20the%20literature&amp;journal=Case%20Rep%20Oncol%20Med&amp;doi=10.1155%2F2015%2F431819&amp;volume=2015&amp;publication_year=2015&amp;author=Khattab%2CMH&amp;author=Marciscano%2CAE&amp;author=Lo%2CSS&amp;author=Lim%2CM&amp;author=Laterra%2CJJ&amp;author=Kleinberg%2CLR&amp;author=Redmond%2CKJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR22\">Kleinschmidt-DeMasters BK, Gilani A (2022) Extra-CNS and dural metastases in FGFR3::TACC3 fusion+ adult glioblastoma, IDH-wildtype. Neuro-Oncol Pract 9:449\u2013455. <a href=\"https:\/\/doi.org\/10.1093\/nop\/npac042\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/nop\/npac042\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/nop\/npac042<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/nop\/npac042\" data-track-item_id=\"10.1093\/nop\/npac042\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fnop%2Fnpac042\" aria-label=\"Article reference 22\" data-doi=\"10.1093\/nop\/npac042\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DC%2BB287osFejtg%3D%3D\" aria-label=\"CAS reference 22\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 22\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extra-CNS%20and%20dural%20metastases%20in%20FGFR3%3A%3ATACC3%20fusion%2B%20adult%20glioblastoma%2C%20IDH-wildtype&amp;journal=Neuro-Oncol%20Pract&amp;doi=10.1093%2Fnop%2Fnpac042&amp;volume=9&amp;pages=449-455&amp;publication_year=2022&amp;author=Kleinschmidt-DeMasters%2CBK&amp;author=Gilani%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR23\">Komatsu K, Hiratsuka H, Takahashi S, Kamisasa A, Inaba Y (1972) Widespread extracranial metastases of glioblastoma multiforme. Report of case and clinicopathological review of cases in literature. Bull Tokyo Med Dent Univ 19:29\u201349<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaE383gvV2hsw%3D%3D\" aria-label=\"CAS reference 23\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=4338365\" aria-label=\"PubMed reference 23\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 23\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Widespread%20extracranial%20metastases%20of%20glioblastoma%20multiforme.%20Report%20of%20case%20and%20clinicopathological%20review%20of%20cases%20in%20literature&amp;journal=Bull%20Tokyo%20Med%20Dent%20Univ&amp;volume=19&amp;pages=29-49&amp;publication_year=1972&amp;author=Komatsu%2CK&amp;author=Hiratsuka%2CH&amp;author=Takahashi%2CS&amp;author=Kamisasa%2CA&amp;author=Inaba%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR24\">Kumaria A, Teale A, Kulkarni GV, Ingale HA, Macarthur DC, Robertson IJA (2022) Glioblastoma multiforme metastatic to lung in the absence of intracranial recurrence: case report. Br J Neurosurg 36:290\u2013292. <a href=\"https:\/\/doi.org\/10.1080\/02688697.2018.1529296\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1080\/02688697.2018.1529296\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1080\/02688697.2018.1529296<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1080\/02688697.2018.1529296\" data-track-item_id=\"10.1080\/02688697.2018.1529296\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1080%2F02688697.2018.1529296\" aria-label=\"Article reference 24\" data-doi=\"10.1080\/02688697.2018.1529296\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30450987\" aria-label=\"PubMed reference 24\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 24\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Glioblastoma%20multiforme%20metastatic%20to%20lung%20in%20the%20absence%20of%20intracranial%20recurrence%3A%20case%20report&amp;journal=Br%20J%20Neurosurg&amp;doi=10.1080%2F02688697.2018.1529296&amp;volume=36&amp;pages=290-292&amp;publication_year=2022&amp;author=Kumaria%2CA&amp;author=Teale%2CA&amp;author=Kulkarni%2CGV&amp;author=Ingale%2CHA&amp;author=Macarthur%2CDC&amp;author=Robertson%2CIJA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR25\">Lasorella A, Sanson M, Iavarone A (2017) FGFR-TACC gene fusions in human glioma. Neuro Oncol 19:475\u2013483. <a href=\"https:\/\/doi.org\/10.1093\/neuonc\/now240\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/neuonc\/now240\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/neuonc\/now240<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/neuonc\/now240\" data-track-item_id=\"10.1093\/neuonc\/now240\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fneuonc%2Fnow240\" aria-label=\"Article reference 25\" data-doi=\"10.1093\/neuonc\/now240\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXitFSnt73N\" aria-label=\"CAS reference 25\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27852792\" aria-label=\"PubMed reference 25\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 25\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=FGFR-TACC%20gene%20fusions%20in%20human%20glioma&amp;journal=Neuro%20Oncol&amp;doi=10.1093%2Fneuonc%2Fnow240&amp;volume=19&amp;pages=475-483&amp;publication_year=2017&amp;author=Lasorella%2CA&amp;author=Sanson%2CM&amp;author=Iavarone%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR26\">Laurin BJ, Treffy R, Connelly JM, Straza M, Mueller WM, Krucoff MO (2024) Mesenchymal-type genetic mutations are likely prerequisite for glioblastoma multiforme to metastasize outside the central nervous system: an original case series and systematic review of the literature. World Neurosurg 193:397\u2013426. <a href=\"https:\/\/doi.org\/10.1016\/j.wneu.2024.09.138\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/j.wneu.2024.09.138\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/j.wneu.2024.09.138<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.wneu.2024.09.138\" data-track-item_id=\"10.1016\/j.wneu.2024.09.138\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.wneu.2024.09.138\" aria-label=\"Article reference 26\" data-doi=\"10.1016\/j.wneu.2024.09.138\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39419169\" aria-label=\"PubMed reference 26\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 26\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mesenchymal-type%20genetic%20mutations%20are%20likely%20prerequisite%20for%20glioblastoma%20multiforme%20to%20metastasize%20outside%20the%20central%20nervous%20system%3A%20an%20original%20case%20series%20and%20systematic%20review%20of%20the%20literature&amp;journal=World%20Neurosurg&amp;doi=10.1016%2Fj.wneu.2024.09.138&amp;volume=193&amp;pages=397-426&amp;publication_year=2024&amp;author=Laurin%2CBJ&amp;author=Treffy%2CR&amp;author=Connelly%2CJM&amp;author=Straza%2CM&amp;author=Mueller%2CWM&amp;author=Krucoff%2CMO\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR27\">Liu J, Shen L, Tang G, Tang S, Kuang W, Li H, Tian Y, Zhou Q (2020) Multiple extracranial metastases from glioblastoma multiforme: a case report and literature review. J Int Med Res 48:300060520930459. <a href=\"https:\/\/doi.org\/10.1177\/0300060520930459\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1177\/0300060520930459\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1177\/0300060520930459<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1177\/0300060520930459\" data-track-item_id=\"10.1177\/0300060520930459\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1177%2F0300060520930459\" aria-label=\"Article reference 27\" data-doi=\"10.1177\/0300060520930459\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32552287\" aria-label=\"PubMed reference 27\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 27\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multiple%20extracranial%20metastases%20from%20glioblastoma%20multiforme%3A%20a%20case%20report%20and%20literature%20review&amp;journal=J%20Int%20Med%20Res&amp;doi=10.1177%2F0300060520930459&amp;volume=48&amp;publication_year=2020&amp;author=Liu%2CJ&amp;author=Shen%2CL&amp;author=Tang%2CG&amp;author=Tang%2CS&amp;author=Kuang%2CW&amp;author=Li%2CH&amp;author=Tian%2CY&amp;author=Zhou%2CQ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR28\">Loriot Y, Necchi A, Park SH, Garcia-Donas J, Huddart R, Burgess E, Fleming M, Rezazadeh A, Mellado B, Varlamov S et al (2019) Erdafitinib in locally advanced or metastatic urothelial carcinoma. N Engl J Med 381:338\u2013348. <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa1817323\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1056\/NEJMoa1817323\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1056\/NEJMoa1817323<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1056\/NEJMoa1817323\" data-track-item_id=\"10.1056\/NEJMoa1817323\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1056%2FNEJMoa1817323\" aria-label=\"Article reference 28\" data-doi=\"10.1056\/NEJMoa1817323\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXnsFCqt7w%3D\" aria-label=\"CAS reference 28\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31340094\" aria-label=\"PubMed reference 28\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 28\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Erdafitinib%20in%20locally%20advanced%20or%20metastatic%20urothelial%20carcinoma&amp;journal=N%20Engl%20J%20Med&amp;doi=10.1056%2FNEJMoa1817323&amp;volume=381&amp;pages=338-348&amp;publication_year=2019&amp;author=Loriot%2CY&amp;author=Necchi%2CA&amp;author=Park%2CSH&amp;author=Garcia-Donas%2CJ&amp;author=Huddart%2CR&amp;author=Burgess%2CE&amp;author=Fleming%2CM&amp;author=Rezazadeh%2CA&amp;author=Mellado%2CB&amp;author=Varlamov%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR29\">Louveau A, Smirnov I, Keyes TJ, Eccles JD, Rouhani SJ, Peske JD, Derecki NC, Castle D, Mandell JW, Lee KS et al (2015) Structural and functional features of central nervous system lymphatic vessels. Nature 523:337\u2013341. <a href=\"https:\/\/doi.org\/10.1038\/nature14432\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1038\/nature14432\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1038\/nature14432<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nature14432\" data-track-item_id=\"10.1038\/nature14432\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnature14432\" aria-label=\"Article reference 29\" data-doi=\"10.1038\/nature14432\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXhtFaitrrE\" aria-label=\"CAS reference 29\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26030524\" aria-label=\"PubMed reference 29\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4506234\" aria-label=\"PubMed Central reference 29\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 29\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Structural%20and%20functional%20features%20of%20central%20nervous%20system%20lymphatic%20vessels&amp;journal=Nature&amp;doi=10.1038%2Fnature14432&amp;volume=523&amp;pages=337-341&amp;publication_year=2015&amp;author=Louveau%2CA&amp;author=Smirnov%2CI&amp;author=Keyes%2CTJ&amp;author=Eccles%2CJD&amp;author=Rouhani%2CSJ&amp;author=Peske%2CJD&amp;author=Derecki%2CNC&amp;author=Castle%2CD&amp;author=Mandell%2CJW&amp;author=Lee%2CKS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR30\">Luan XZ, Wang HR, Xiang W, Li SJ, He H, Chen LG, Wang JM, Zhou J (2021) Extracranial multiorgan metastasis from primary glioblastoma: a case report. World J Clin Cases 9:10300\u201310307. <a href=\"https:\/\/doi.org\/10.12998\/wjcc.v9.i33.10300\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.12998\/wjcc.v9.i33.10300\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.12998\/wjcc.v9.i33.10300<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.12998\/wjcc.v9.i33.10300\" data-track-item_id=\"10.12998\/wjcc.v9.i33.10300\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.12998%2Fwjcc.v9.i33.10300\" aria-label=\"Article reference 30\" data-doi=\"10.12998\/wjcc.v9.i33.10300\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34904103\" aria-label=\"PubMed reference 30\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8638031\" aria-label=\"PubMed Central reference 30\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 30\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extracranial%20multiorgan%20metastasis%20from%20primary%20glioblastoma%3A%20a%20case%20report&amp;journal=World%20J%20Clin%20Cases&amp;doi=10.12998%2Fwjcc.v9.i33.10300&amp;volume=9&amp;pages=10300-10307&amp;publication_year=2021&amp;author=Luan%2CXZ&amp;author=Wang%2CHR&amp;author=Xiang%2CW&amp;author=Li%2CSJ&amp;author=He%2CH&amp;author=Chen%2CLG&amp;author=Wang%2CJM&amp;author=Zhou%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR31\">Mata DA, Benhamida JK, Lin AL, Vanderbilt CM, Yang SR, Villafania LB, Ferguson DC, Jonsson P, Miller AM, Tabar V et al (2020) Genetic and epigenetic landscape of IDH-wildtype glioblastomas with FGFR3-TACC3 fusions. Acta Neuropathol Commun 8:186. <a href=\"https:\/\/doi.org\/10.1186\/s40478-020-01058-6\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1186\/s40478-020-01058-6\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1186\/s40478-020-01058-6<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s40478-020-01058-6\" data-track-item_id=\"10.1186\/s40478-020-01058-6\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s40478-020-01058-6\" aria-label=\"Article reference 31\" data-doi=\"10.1186\/s40478-020-01058-6\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXitlOhurjO\" aria-label=\"CAS reference 31\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33168106\" aria-label=\"PubMed reference 31\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7653727\" aria-label=\"PubMed Central reference 31\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 31\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genetic%20and%20epigenetic%20landscape%20of%20IDH-wildtype%20glioblastomas%20with%20FGFR3-TACC3%20fusions&amp;journal=Acta%20Neuropathol%20Commun&amp;doi=10.1186%2Fs40478-020-01058-6&amp;volume=8&amp;publication_year=2020&amp;author=Mata%2CDA&amp;author=Benhamida%2CJK&amp;author=Lin%2CAL&amp;author=Vanderbilt%2CCM&amp;author=Yang%2CSR&amp;author=Villafania%2CLB&amp;author=Ferguson%2CDC&amp;author=Jonsson%2CP&amp;author=Miller%2CAM&amp;author=Tabar%2CV\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR32\">Mathios D, Niknafs N, Annapragada AV, Bobeff EJ, Chiao EJ, Boyapati K, Boyapati K, Short S, Bartolomucci AL, Cristiano S et al (2025) Detection of brain cancer using genome-wide cell-free DNA fragmentomes. Cancer Discov. <a href=\"https:\/\/doi.org\/10.1158\/2159-8290.CD-25-0074\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1158\/2159-8290.CD-25-0074\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1158\/2159-8290.CD-25-0074<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1158\/2159-8290.CD-25-0074\" data-track-item_id=\"10.1158\/2159-8290.CD-25-0074\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1158%2F2159-8290.CD-25-0074\" aria-label=\"Article reference 32\" data-doi=\"10.1158\/2159-8290.CD-25-0074\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=40299319\" aria-label=\"PubMed reference 32\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12319403\" aria-label=\"PubMed Central reference 32\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 32\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Detection%20of%20brain%20cancer%20using%20genome-wide%20cell-free%20DNA%20fragmentomes&amp;journal=Cancer%20Discov&amp;doi=10.1158%2F2159-8290.CD-25-0074&amp;publication_year=2025&amp;author=Mathios%2CD&amp;author=Niknafs%2CN&amp;author=Annapragada%2CAV&amp;author=Bobeff%2CEJ&amp;author=Chiao%2CEJ&amp;author=Boyapati%2CK&amp;author=Boyapati%2CK&amp;author=Short%2CS&amp;author=Bartolomucci%2CAL&amp;author=Cristiano%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR33\">Mujic A, Hunn A, Taylor AB, Lowenthal RM (2006) Extracranial metastases of a glioblastoma multiforme to the pleura, small bowel and pancreas. J Clin Neurosci 13:677\u2013681. <a href=\"https:\/\/doi.org\/10.1016\/j.jocn.2005.08.016\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/j.jocn.2005.08.016\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/j.jocn.2005.08.016<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.jocn.2005.08.016\" data-track-item_id=\"10.1016\/j.jocn.2005.08.016\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.jocn.2005.08.016\" aria-label=\"Article reference 33\" data-doi=\"10.1016\/j.jocn.2005.08.016\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DC%2BD28vjslertA%3D%3D\" aria-label=\"CAS reference 33\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16815020\" aria-label=\"PubMed reference 33\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 33\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extracranial%20metastases%20of%20a%20glioblastoma%20multiforme%20to%20the%20pleura%2C%20small%20bowel%20and%20pancreas&amp;journal=J%20Clin%20Neurosci&amp;doi=10.1016%2Fj.jocn.2005.08.016&amp;volume=13&amp;pages=677-681&amp;publication_year=2006&amp;author=Mujic%2CA&amp;author=Hunn%2CA&amp;author=Taylor%2CAB&amp;author=Lowenthal%2CRM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR34\">M\u00fcller C, Holtschmidt J, Auer M, Heitzer E, Lamszus K, Schulte A, Matschke J, Langer-Freitag S, Gasch C, Stoupiec M et al (2014) Hematogenous dissemination of glioblastoma multiforme. Sci Transl Med. <a href=\"https:\/\/doi.org\/10.1126\/scitranslmed.3009095\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1126\/scitranslmed.3009095\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1126\/scitranslmed.3009095<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/scitranslmed.3009095\" data-track-item_id=\"10.1126\/scitranslmed.3009095\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fscitranslmed.3009095\" aria-label=\"Article reference 34\" data-doi=\"10.1126\/scitranslmed.3009095\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25391483\" aria-label=\"PubMed reference 34\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4372245\" aria-label=\"PubMed Central reference 34\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 34\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Hematogenous%20dissemination%20of%20glioblastoma%20multiforme&amp;journal=Sci%20Transl%20Med&amp;doi=10.1126%2Fscitranslmed.3009095&amp;publication_year=2014&amp;author=M%C3%BCller%2CC&amp;author=Holtschmidt%2CJ&amp;author=Auer%2CM&amp;author=Heitzer%2CE&amp;author=Lamszus%2CK&amp;author=Schulte%2CA&amp;author=Matschke%2CJ&amp;author=Langer-Freitag%2CS&amp;author=Gasch%2CC&amp;author=Stoupiec%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR35\">Noch EK, Sait SF, Farooq S, Trippett TM, Miller AM (2021) A case series of extraneural metastatic glioblastoma at Memorial Sloan Kettering Cancer Center. Neurooncol Pract 8:325\u2013336. <a href=\"https:\/\/doi.org\/10.1093\/nop\/npaa083\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/nop\/npaa083\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/nop\/npaa083<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/nop\/npaa083\" data-track-item_id=\"10.1093\/nop\/npaa083\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fnop%2Fnpaa083\" aria-label=\"Article reference 35\" data-doi=\"10.1093\/nop\/npaa083\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34055380\" aria-label=\"PubMed reference 35\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8153825\" aria-label=\"PubMed Central reference 35\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 35\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20case%20series%20of%20extraneural%20metastatic%20glioblastoma%20at%20Memorial%20Sloan%20Kettering%20Cancer%20Center&amp;journal=Neurooncol%20Pract&amp;doi=10.1093%2Fnop%2Fnpaa083&amp;volume=8&amp;pages=325-336&amp;publication_year=2021&amp;author=Noch%2CEK&amp;author=Sait%2CSF&amp;author=Farooq%2CS&amp;author=Trippett%2CTM&amp;author=Miller%2CAM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR36\">Ogungbo BI, Perry RH, Bozzino J, Mahadeva D (2005) Report of GBM metastasis to the parotid gland. J Neurooncol 74:337\u2013338. <a href=\"https:\/\/doi.org\/10.1007\/s11060-005-1480-9\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1007\/s11060-005-1480-9\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1007\/s11060-005-1480-9<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s11060-005-1480-9\" data-track-item_id=\"10.1007\/s11060-005-1480-9\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s11060-005-1480-9\" aria-label=\"Article reference 36\" data-doi=\"10.1007\/s11060-005-1480-9\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DC%2BD2MrhtlOjsw%3D%3D\" aria-label=\"CAS reference 36\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16132510\" aria-label=\"PubMed reference 36\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 36\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Report%20of%20GBM%20metastasis%20to%20the%20parotid%20gland&amp;journal=J%20Neurooncol&amp;doi=10.1007%2Fs11060-005-1480-9&amp;volume=74&amp;pages=337-338&amp;publication_year=2005&amp;author=Ogungbo%2CBI&amp;author=Perry%2CRH&amp;author=Bozzino%2CJ&amp;author=Mahadeva%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR37\">Ostrom QT, Price M, Neff C, Cioffi G, Waite KA, Kruchko C, Barnholtz-Sloan JS (2023) CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2016\u20132020. Neuro Oncol 25:iv1\u2013iv99. <a href=\"https:\/\/doi.org\/10.1093\/neuonc\/noad149\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/neuonc\/noad149\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/neuonc\/noad149<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/neuonc\/noad149\" data-track-item_id=\"10.1093\/neuonc\/noad149\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fneuonc%2Fnoad149\" aria-label=\"Article reference 37\" data-doi=\"10.1093\/neuonc\/noad149\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37793125\" aria-label=\"PubMed reference 37\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10550277\" aria-label=\"PubMed Central reference 37\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 37\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=CBTRUS%20statistical%20report%3A%20primary%20brain%20and%20other%20central%20nervous%20system%20tumors%20diagnosed%20in%20the%20United%20States%20in%202016%E2%80%932020&amp;journal=Neuro%20Oncol&amp;doi=10.1093%2Fneuonc%2Fnoad149&amp;volume=25&amp;pages=iv1-iv99&amp;publication_year=2023&amp;author=Ostrom%2CQT&amp;author=Price%2CM&amp;author=Neff%2CC&amp;author=Cioffi%2CG&amp;author=Waite%2CKA&amp;author=Kruchko%2CC&amp;author=Barnholtz-Sloan%2CJS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR38\">Piccirilli M, Brunetto GM, Rocchi G, Giangaspero F, Salvati M (2008) Extra central nervous system metastases from cerebral glioblastoma multiforme in elderly patients. Clinico-pathological remarks on our series of seven cases and critical review of the literature. Tumori 94:40\u201351. <a href=\"https:\/\/doi.org\/10.1177\/030089160809400109\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1177\/030089160809400109\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1177\/030089160809400109<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1177\/030089160809400109\" data-track-item_id=\"10.1177\/030089160809400109\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1177%2F030089160809400109\" aria-label=\"Article reference 38\" data-doi=\"10.1177\/030089160809400109\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=18468334\" aria-label=\"PubMed reference 38\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 38\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extra%20central%20nervous%20system%20metastases%20from%20cerebral%20glioblastoma%20multiforme%20in%20elderly%20patients.%20Clinico-pathological%20remarks%20on%20our%20series%20of%20seven%20cases%20and%20critical%20review%20of%20the%20literature&amp;journal=Tumori&amp;doi=10.1177%2F030089160809400109&amp;volume=94&amp;pages=40-51&amp;publication_year=2008&amp;author=Piccirilli%2CM&amp;author=Brunetto%2CGM&amp;author=Rocchi%2CG&amp;author=Giangaspero%2CF&amp;author=Salvati%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR39\">Pi\u00f1a-Oviedo S, De Le\u00f3n-Bojorge B, Cuesta-Mej\u00edas T, White MK, Ortiz-Hidalgo C, Khalili K, Del Valle L (2006) Glioblastoma multiforme with small cell neuronal-like component: association with human neurotropic JC virus. Acta Neuropathol 111:388\u2013396. <a href=\"https:\/\/doi.org\/10.1007\/s00401-006-0050-3\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1007\/s00401-006-0050-3\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1007\/s00401-006-0050-3<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s00401-006-0050-3\" data-track-item_id=\"10.1007\/s00401-006-0050-3\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s00401-006-0050-3\" aria-label=\"Article reference 39\" data-doi=\"10.1007\/s00401-006-0050-3\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16557392\" aria-label=\"PubMed reference 39\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 39\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Glioblastoma%20multiforme%20with%20small%20cell%20neuronal-like%20component%3A%20association%20with%20human%20neurotropic%20JC%20virus&amp;journal=Acta%20Neuropathol&amp;doi=10.1007%2Fs00401-006-0050-3&amp;volume=111&amp;pages=388-396&amp;publication_year=2006&amp;author=Pi%C3%B1a-Oviedo%2CS&amp;author=Le%C3%B3n-Bojorge%2CB&amp;author=Cuesta-Mej%C3%ADas%2CT&amp;author=White%2CMK&amp;author=Ortiz-Hidalgo%2CC&amp;author=Khalili%2CK&amp;author=Valle%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR40\">Prabhakaran N, Miller DC, Litofsky NS, Frazier SR (2019) Extraneural metastasis of primary glioma occurring in a setting of occupational ionizing radiation exposure. Case Rep Neurol Med 2019:1748739. <a href=\"https:\/\/doi.org\/10.1155\/2019\/1748739\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1155\/2019\/1748739\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1155\/2019\/1748739<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1155\/2019\/1748739\" data-track-item_id=\"10.1155\/2019\/1748739\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1155%2F2019%2F1748739\" aria-label=\"Article reference 40\" data-doi=\"10.1155\/2019\/1748739\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31312534\" aria-label=\"PubMed reference 40\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6595336\" aria-label=\"PubMed Central reference 40\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 40\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extraneural%20metastasis%20of%20primary%20glioma%20occurring%20in%20a%20setting%20of%20occupational%20ionizing%20radiation%20exposure&amp;journal=Case%20Rep%20Neurol%20Med&amp;doi=10.1155%2F2019%2F1748739&amp;volume=2019&amp;publication_year=2019&amp;author=Prabhakaran%2CN&amp;author=Miller%2CDC&amp;author=Litofsky%2CNS&amp;author=Frazier%2CSR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR41\">Ray A, Manjila S, Hdeib AM, Radhakrishnan A, Nock CJ, Cohen ML, Sloan AE (2015) Extracranial metastasis of gliobastoma: three illustrative cases and current review of the molecular pathology and management strategies. Mol Clin Oncol 3:479\u2013486. <a href=\"https:\/\/doi.org\/10.3892\/mco.2015.494\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.3892\/mco.2015.494\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.3892\/mco.2015.494<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3892\/mco.2015.494\" data-track-item_id=\"10.3892\/mco.2015.494\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3892%2Fmco.2015.494\" aria-label=\"Article reference 41\" data-doi=\"10.3892\/mco.2015.494\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXlsFGrurk%3D\" aria-label=\"CAS reference 41\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26137254\" aria-label=\"PubMed reference 41\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4471516\" aria-label=\"PubMed Central reference 41\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 41\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extracranial%20metastasis%20of%20gliobastoma%3A%20three%20illustrative%20cases%20and%20current%20review%20of%20the%20molecular%20pathology%20and%20management%20strategies&amp;journal=Mol%20Clin%20Oncol&amp;doi=10.3892%2Fmco.2015.494&amp;volume=3&amp;pages=479-486&amp;publication_year=2015&amp;author=Ray%2CA&amp;author=Manjila%2CS&amp;author=Hdeib%2CAM&amp;author=Radhakrishnan%2CA&amp;author=Nock%2CCJ&amp;author=Cohen%2CML&amp;author=Sloan%2CAE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR42\">Sami A, Karsy M (2013) Targeting the PI3K\/AKT\/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding. Tumor Biol 34:1991\u20132002. <a href=\"https:\/\/doi.org\/10.1007\/s13277-013-0800-5\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1007\/s13277-013-0800-5\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1007\/s13277-013-0800-5<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s13277-013-0800-5\" data-track-item_id=\"10.1007\/s13277-013-0800-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s13277-013-0800-5\" aria-label=\"Article reference 42\" data-doi=\"10.1007\/s13277-013-0800-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3sXhtFWjsr%2FL\" aria-label=\"CAS reference 42\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 42\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Targeting%20the%20PI3K%2FAKT%2FmTOR%20signaling%20pathway%20in%20glioblastoma%3A%20novel%20therapeutic%20agents%20and%20advances%20in%20understanding&amp;journal=Tumor%20Biol&amp;doi=10.1007%2Fs13277-013-0800-5&amp;volume=34&amp;pages=1991-2002&amp;publication_year=2013&amp;author=Sami%2CA&amp;author=Karsy%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR43\">Seoane J, De Mattos-Arruda L (2014) Escaping out of the brain. Cancer Discov 4:1259\u20131261. <a href=\"https:\/\/doi.org\/10.1158\/2159-8290.CD-14-1178\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1158\/2159-8290.CD-14-1178\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1158\/2159-8290.CD-14-1178<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1158\/2159-8290.CD-14-1178\" data-track-item_id=\"10.1158\/2159-8290.CD-14-1178\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1158%2F2159-8290.CD-14-1178\" aria-label=\"Article reference 43\" data-doi=\"10.1158\/2159-8290.CD-14-1178\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXhvVyju7jK\" aria-label=\"CAS reference 43\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25367947\" aria-label=\"PubMed reference 43\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 43\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Escaping%20out%20of%20the%20brain&amp;journal=Cancer%20Discov&amp;doi=10.1158%2F2159-8290.CD-14-1178&amp;volume=4&amp;pages=1259-1261&amp;publication_year=2014&amp;author=Seoane%2CJ&amp;author=Mattos-Arruda%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR44\">Smith DR, Hardman JM, Earle KM (1969) Contiguous glioblastoma multiforme and fibrosarcoma with extracranial metastasis. Cancer 24:270\u2013276. <a href=\"https:\/\/doi.org\/10.1002\/1097-0142(196908)24\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1002\/1097-0142(196908)24\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1002\/1097-0142(196908)24<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/1097-0142(196908)24\" data-track-item_id=\"10.1002\/1097-0142(196908)24\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2F1097-0142%28196908%2924\" aria-label=\"Article reference 44\" data-doi=\"10.1002\/1097-0142(196908)24\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaF1M3ktFCmsw%3D%3D\" aria-label=\"CAS reference 44\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=4307749\" aria-label=\"PubMed reference 44\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 44\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Contiguous%20glioblastoma%20multiforme%20and%20fibrosarcoma%20with%20extracranial%20metastasis&amp;journal=Cancer&amp;doi=10.1002%2F1097-0142%28196908%2924&amp;volume=24&amp;pages=270-276&amp;publication_year=1969&amp;author=Smith%2CDR&amp;author=Hardman%2CJM&amp;author=Earle%2CKM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR45\">Smith DR, Hardman JM, Earle KM (1969) Metastasizing neuroectodermal tumors of the central nervous system. J Neurosurg 31:50\u201358. <a href=\"https:\/\/doi.org\/10.3171\/jns.1969.31.1.0050\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.3171\/jns.1969.31.1.0050\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.3171\/jns.1969.31.1.0050<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3171\/jns.1969.31.1.0050\" data-track-item_id=\"10.3171\/jns.1969.31.1.0050\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3171%2Fjns.1969.31.1.0050\" aria-label=\"Article reference 45\" data-doi=\"10.3171\/jns.1969.31.1.0050\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaF1M3js12nsg%3D%3D\" aria-label=\"CAS reference 45\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=4307543\" aria-label=\"PubMed reference 45\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 45\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Metastasizing%20neuroectodermal%20tumors%20of%20the%20central%20nervous%20system&amp;journal=J%20Neurosurg&amp;doi=10.3171%2Fjns.1969.31.1.0050&amp;volume=31&amp;pages=50-58&amp;publication_year=1969&amp;author=Smith%2CDR&amp;author=Hardman%2CJM&amp;author=Earle%2CKM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR46\">Stupp R, Mason WP, Van Den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352:987\u2013996<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1056\/NEJMoa043330\" data-track-item_id=\"10.1056\/NEJMoa043330\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1056%2FNEJMoa043330\" aria-label=\"Article reference 46\" data-doi=\"10.1056\/NEJMoa043330\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2MXit1Wksbk%3D\" aria-label=\"CAS reference 46\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=15758009\" aria-label=\"PubMed reference 46\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 46\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Radiotherapy%20plus%20concomitant%20and%20adjuvant%20temozolomide%20for%20glioblastoma&amp;journal=N%20Engl%20J%20Med&amp;doi=10.1056%2FNEJMoa043330&amp;volume=352&amp;pages=987-996&amp;publication_year=2005&amp;author=Stupp%2CR&amp;author=Mason%2CWP&amp;author=Bent%2CMJ&amp;author=Weller%2CM&amp;author=Fisher%2CB&amp;author=Taphoorn%2CMJ&amp;author=Belanger%2CK&amp;author=Brandes%2CAA&amp;author=Marosi%2CC&amp;author=Bogdahn%2CU\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR47\">Sullivan JP, Nahed BV, Madden MW, Oliveira SM, Springer S, Bhere D, Chi AS, Wakimoto H, Rothenberg SM, Sequist LV et al (2014) Brain tumor cells in circulation are enriched for mesenchymal gene expression. Cancer Discov 4:1299\u20131309. <a href=\"https:\/\/doi.org\/10.1158\/2159-8290.CD-14-0471\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1158\/2159-8290.CD-14-0471\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1158\/2159-8290.CD-14-0471<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1158\/2159-8290.CD-14-0471\" data-track-item_id=\"10.1158\/2159-8290.CD-14-0471\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1158%2F2159-8290.CD-14-0471\" aria-label=\"Article reference 47\" data-doi=\"10.1158\/2159-8290.CD-14-0471\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXhvVyju7bO\" aria-label=\"CAS reference 47\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25139148\" aria-label=\"PubMed reference 47\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4221467\" aria-label=\"PubMed Central reference 47\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 47\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Brain%20tumor%20cells%20in%20circulation%20are%20enriched%20for%20mesenchymal%20gene%20expression&amp;journal=Cancer%20Discov&amp;doi=10.1158%2F2159-8290.CD-14-0471&amp;volume=4&amp;pages=1299-1309&amp;publication_year=2014&amp;author=Sullivan%2CJP&amp;author=Nahed%2CBV&amp;author=Madden%2CMW&amp;author=Oliveira%2CSM&amp;author=Springer%2CS&amp;author=Bhere%2CD&amp;author=Chi%2CAS&amp;author=Wakimoto%2CH&amp;author=Rothenberg%2CSM&amp;author=Sequist%2CLV\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR48\">Swinnen J, Gelin G, Fransis S, Vandevenne J, Van Cauter S (2019) Glioblastoma with extracranial parotid, lymph node, and pulmonary metastases: a case report. Radiol Case Rep 14:1334\u20131347. <a href=\"https:\/\/doi.org\/10.1016\/j.radcr.2019.08.011\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/j.radcr.2019.08.011\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/j.radcr.2019.08.011<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.radcr.2019.08.011\" data-track-item_id=\"10.1016\/j.radcr.2019.08.011\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.radcr.2019.08.011\" aria-label=\"Article reference 48\" data-doi=\"10.1016\/j.radcr.2019.08.011\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31516649\" aria-label=\"PubMed reference 48\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6732724\" aria-label=\"PubMed Central reference 48\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 48\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Glioblastoma%20with%20extracranial%20parotid%2C%20lymph%20node%2C%20and%20pulmonary%20metastases%3A%20a%20case%20report&amp;journal=Radiol%20Case%20Rep&amp;doi=10.1016%2Fj.radcr.2019.08.011&amp;volume=14&amp;pages=1334-1347&amp;publication_year=2019&amp;author=Swinnen%2CJ&amp;author=Gelin%2CG&amp;author=Fransis%2CS&amp;author=Vandevenne%2CJ&amp;author=Van%20Cauter%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR49\">Tamai S, Kinoshita M, Sabit H, Furuta T, Miyashita K, Yoshimura K, Homma T, Harada K, Nakada M (2019) Case of metastatic glioblastoma with primitive neuronal component to the lung. Neuropathology 39:218\u2013223. <a href=\"https:\/\/doi.org\/10.1111\/neup.12553\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1111\/neup.12553\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1111\/neup.12553<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/neup.12553\" data-track-item_id=\"10.1111\/neup.12553\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fneup.12553\" aria-label=\"Article reference 49\" data-doi=\"10.1111\/neup.12553\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31025405\" aria-label=\"PubMed reference 49\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 49\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Case%20of%20metastatic%20glioblastoma%20with%20primitive%20neuronal%20component%20to%20the%20lung&amp;journal=Neuropathology&amp;doi=10.1111%2Fneup.12553&amp;volume=39&amp;pages=218-223&amp;publication_year=2019&amp;author=Tamai%2CS&amp;author=Kinoshita%2CM&amp;author=Sabit%2CH&amp;author=Furuta%2CT&amp;author=Miyashita%2CK&amp;author=Yoshimura%2CK&amp;author=Homma%2CT&amp;author=Harada%2CK&amp;author=Nakada%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR50\">Templeton A, Hofer S, T\u00f6pfer M, Sommacal A, Fretz C, Cerny T, Gillessen S (2008) Extraneural spread of glioblastoma\u2013report of two cases. Onkologie 31:192\u2013194. <a href=\"https:\/\/doi.org\/10.1159\/000118627\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1159\/000118627\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1159\/000118627<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1159\/000118627\" data-track-item_id=\"10.1159\/000118627\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1159%2F000118627\" aria-label=\"Article reference 50\" data-doi=\"10.1159\/000118627\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=18418021\" aria-label=\"PubMed reference 50\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 50\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extraneural%20spread%20of%20glioblastoma%E2%80%93report%20of%20two%20cases&amp;journal=Onkologie&amp;doi=10.1159%2F000118627&amp;volume=31&amp;pages=192-194&amp;publication_year=2008&amp;author=Templeton%2CA&amp;author=Hofer%2CS&amp;author=T%C3%B6pfer%2CM&amp;author=Sommacal%2CA&amp;author=Fretz%2CC&amp;author=Cerny%2CT&amp;author=Gillessen%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR51\">Umphlett M, Shea S, Tome-Garcia J, Zhang Y, Hormigo A, Fowkes M, Tsankova NM, Yong RL (2020) Widely metastatic glioblastoma with BRCA1 and ARID1A mutations: a case report. BMC Cancer 20:47. <a href=\"https:\/\/doi.org\/10.1186\/s12885-020-6540-1\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1186\/s12885-020-6540-1\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1186\/s12885-020-6540-1<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12885-020-6540-1\" data-track-item_id=\"10.1186\/s12885-020-6540-1\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12885-020-6540-1\" aria-label=\"Article reference 51\" data-doi=\"10.1186\/s12885-020-6540-1\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXksFant7g%3D\" aria-label=\"CAS reference 51\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31959133\" aria-label=\"PubMed reference 51\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6971940\" aria-label=\"PubMed Central reference 51\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 51\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Widely%20metastatic%20glioblastoma%20with%20BRCA1%20and%20ARID1A%20mutations%3A%20a%20case%20report&amp;journal=BMC%20Cancer&amp;doi=10.1186%2Fs12885-020-6540-1&amp;volume=20&amp;publication_year=2020&amp;author=Umphlett%2CM&amp;author=Shea%2CS&amp;author=Tome-Garcia%2CJ&amp;author=Zhang%2CY&amp;author=Hormigo%2CA&amp;author=Fowkes%2CM&amp;author=Tsankova%2CNM&amp;author=Yong%2CRL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR52\">Undabeitia J, Castle M, Arrazola M, Pendleton C, Ruiz I, \u00darculo E (2015) Multiple extraneural metastasis of glioblastoma multiforme. An Sist Sanit Navar 38:157\u2013161. <a href=\"https:\/\/doi.org\/10.23938\/assn.0061\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.23938\/assn.0061\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.23938\/assn.0061<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.23938\/assn.0061\" data-track-item_id=\"10.23938\/assn.0061\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.23938%2Fassn.0061\" aria-label=\"Article reference 52\" data-doi=\"10.23938\/assn.0061\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DC%2BC28%2FhvFKmtQ%3D%3D\" aria-label=\"CAS reference 52\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25963474\" aria-label=\"PubMed reference 52\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 52\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multiple%20extraneural%20metastasis%20of%20glioblastoma%20multiforme&amp;journal=An%20Sist%20Sanit%20Navar&amp;doi=10.23938%2Fassn.0061&amp;volume=38&amp;pages=157-161&amp;publication_year=2015&amp;author=Undabeitia%2CJ&amp;author=Castle%2CM&amp;author=Arrazola%2CM&amp;author=Pendleton%2CC&amp;author=Ruiz%2CI&amp;author=%C3%9Arculo%2CE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR53\">Wakamatsu T, Matsuo T, Kawano S, Teramoto S, Matsumura H (1972) Extracranial metastasis of intracranial tumor\u2013review of literatures and report of a case. Acta Pathol Jpn 22:155\u2013169. <a href=\"https:\/\/doi.org\/10.1111\/j.1440-1827.1972.tb01838.x\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1111\/j.1440-1827.1972.tb01838.x\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1111\/j.1440-1827.1972.tb01838.x<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1440-1827.1972.tb01838.x\" data-track-item_id=\"10.1111\/j.1440-1827.1972.tb01838.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1440-1827.1972.tb01838.x\" aria-label=\"Article reference 53\" data-doi=\"10.1111\/j.1440-1827.1972.tb01838.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DyaE383msFeqtQ%3D%3D\" aria-label=\"CAS reference 53\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=4341291\" aria-label=\"PubMed reference 53\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 53\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Extracranial%20metastasis%20of%20intracranial%20tumor%E2%80%93review%20of%20literatures%20and%20report%20of%20a%20case&amp;journal=Acta%20Pathol%20Jpn&amp;doi=10.1111%2Fj.1440-1827.1972.tb01838.x&amp;volume=22&amp;pages=155-169&amp;publication_year=1972&amp;author=Wakamatsu%2CT&amp;author=Matsuo%2CT&amp;author=Kawano%2CS&amp;author=Teramoto%2CS&amp;author=Matsumura%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR54\">Walker DG, Pamphlett R (1999) Prolonged survival and pulmonary metastasis after local cure of glioblastoma multiforme. J Clin Neurosci 6:67\u201368. <a href=\"https:\/\/doi.org\/10.1016\/s0967-5868(99)90611-2\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/s0967-5868(99)90611-2\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/s0967-5868(99)90611-2<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/s0967-5868(99)90611-2\" data-track-item_id=\"10.1016\/s0967-5868(99)90611-2\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fs0967-5868%2899%2990611-2\" aria-label=\"Article reference 54\" data-doi=\"10.1016\/s0967-5868(99)90611-2\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/cas-redirect\/1:STN:280:DC%2BD1cvmt12rtQ%3D%3D\" aria-label=\"CAS reference 54\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=18639130\" aria-label=\"PubMed reference 54\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 54\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Prolonged%20survival%20and%20pulmonary%20metastasis%20after%20local%20cure%20of%20glioblastoma%20multiforme&amp;journal=J%20Clin%20Neurosci&amp;doi=10.1016%2Fs0967-5868%2899%2990611-2&amp;volume=6&amp;pages=67-68&amp;publication_year=1999&amp;author=Walker%2CDG&amp;author=Pamphlett%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR55\">Yang G, Fang Y, Zhou M, Li W, Dong D, Chen J, Da Y, Wang K, Li X, Zhang X et al (2022) Case report: the effective response to pembrolizumab in combination with bevacizumab in the treatment of a recurrent glioblastoma with multiple extracranial metastases. Front Oncol 12:948933. <a href=\"https:\/\/doi.org\/10.3389\/fonc.2022.948933\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.3389\/fonc.2022.948933\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.3389\/fonc.2022.948933<\/a><\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3389\/fonc.2022.948933\" data-track-item_id=\"10.3389\/fonc.2022.948933\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3389%2Ffonc.2022.948933\" aria-label=\"Article reference 55\" data-doi=\"10.3389\/fonc.2022.948933\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36052225\" aria-label=\"PubMed reference 55\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9424992\" aria-label=\"PubMed Central reference 55\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 55\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Case%20report%3A%20the%20effective%20response%20to%20pembrolizumab%20in%20combination%20with%20bevacizumab%20in%20the%20treatment%20of%20a%20recurrent%20glioblastoma%20with%20multiple%20extracranial%20metastases&amp;journal=Front%20Oncol&amp;doi=10.3389%2Ffonc.2022.948933&amp;volume=12&amp;publication_year=2022&amp;author=Yang%2CG&amp;author=Fang%2CY&amp;author=Zhou%2CM&amp;author=Li%2CW&amp;author=Dong%2CD&amp;author=Chen%2CJ&amp;author=Da%2CY&amp;author=Wang%2CK&amp;author=Li%2CX&amp;author=Zhang%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n","protected":false},"excerpt":{"rendered":"Achi J, Achi XW, Veintimilla P, Cueva J (2023) Unusual extraneural metastasis of glioblastoma. Surg Neurol Int 14:218.&hellip;\n","protected":false},"author":2,"featured_media":112949,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[114,73110,73112,34494,4450,85,46,73111,10712,168,4748,10744,73113],"class_list":{"0":"post-112948","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-business","8":"tag-business","9":"tag-cfdna","10":"tag-fgfr3tacc3","11":"tag-fragmentation","12":"tag-glioblastoma","13":"tag-il","14":"tag-israel","15":"tag-liquid-biopsy","16":"tag-metastasis","17":"tag-neurology","18":"tag-neurosciences","19":"tag-pathology","20":"tag-systematic-review"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/112948","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=112948"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/112948\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/112949"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=112948"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=112948"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=112948"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}