{"id":129064,"date":"2025-11-12T10:05:08","date_gmt":"2025-11-12T10:05:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/129064\/"},"modified":"2025-11-12T10:05:08","modified_gmt":"2025-11-12T10:05:08","slug":"ausdocs-quick-guide-to-the-physiological-effects-of-15-antidepressants","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/129064\/","title":{"rendered":"AusDoc&#8217;s quick guide to the physiological effects of 15 antidepressants"},"content":{"rendered":"<p>Recent large-scale research has put the spotlight on a nuance that often looms under the surface of antidepressant prescribing: not all antidepressants are physiologically equal. <\/p>\n<p>A new systematic review and network meta-analysis of 151 trials, involving more than 58,000 patients, found clinically meaningful differences between drugs in weight change, heart rate and blood pressure \u2014even within 6-8 weeks of treatment.<\/p>\n<p>AusDoc has developed a guide that summarises the most relevant physiological effects of commonly prescribed antidepressants based on the study, which was published in The Lancet.<\/p>\n<p class=\"has-small-font-size\">Methodological note: Data from Pillinger et al., The Lancet (2025). Approximate short-term (6-8 week) changes in weight, cardiometabolic and hepatic markers were derived from reported mean differences and standardised mean differences, converted to clinically relevant estimates using a pooled standard deviation of \u2248 2 kg for weight and qualitative summaries for other measures.<\/p>\n<p>\t\t\u00d7<\/p>\n<p>\n\t\t\t\tSign in\n\t\t\t<\/p>\n<p class=\"d-none message adg-password-reset\">\n\t\t\t\tIf this is your first visit to the new AusDoc website, reset your password<br \/>\n\t\t\t\t<a class=\"adg-reset_password_link\" href=\"https:\/\/www.ausdoc.com.au\/wp-login.php?action=lostpassword\" target=\"_blank\" rel=\"nofollow noopener\">here.<\/a>\n\t\t\t<\/p>\n","protected":false},"excerpt":{"rendered":"Recent large-scale research has put the spotlight on a nuance that often looms under the surface of antidepressant&hellip;\n","protected":false},"author":2,"featured_media":129065,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[48494,163,85,46,482,43,6006,81052],"class_list":{"0":"post-129064","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-medication","8":"tag-antidepressants","9":"tag-health","10":"tag-il","11":"tag-israel","12":"tag-medication","13":"tag-news","14":"tag-prescribing","15":"tag-psychiatry-psychology"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/129064","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=129064"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/129064\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/129065"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=129064"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=129064"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=129064"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}