{"id":141552,"date":"2025-11-19T11:04:07","date_gmt":"2025-11-19T11:04:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/141552\/"},"modified":"2025-11-19T11:04:07","modified_gmt":"2025-11-19T11:04:07","slug":"systemic-immune-inflammation-index-predicts-acute-histologic-chorioamnionitis-pathologic-staging-and-neonatal-respiratory-distress-syndrome-in-women-with-preterm-premature-rupture-of-membranes-a-retr","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/141552\/","title":{"rendered":"Systemic immune-inflammation index predicts acute histologic chorioamnionitis pathologic staging and neonatal respiratory distress syndrome in women with preterm premature rupture of membranes: a retrospective cohort study | BMC Pregnancy and Childbirth"},"content":{"rendered":"

Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008;371:75\u201384.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Henderson JJ, McWilliam OA, Newnham JP, Pennell CE. Preterm birth aetiology 2004\u20132008. Maternal factors associated with three phenotypes: spontaneous preterm labour, preterm pre-labour rupture of membranes and medically indicated preterm birth. J Matern Fetal Neonatal Med. 2012;25:642\u20137.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Blencowe H, Cousens S, Chou D, Oestergaard M, Say L, Moller AB, et al. Born too soon: the global epidemiology of 15 million preterm births. Reprod Health. 2013;10(Suppl 1):S2.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

DiGiulio DB, Romero R, Kusanovic JP, G\u00f3mez R, Kim CJ, Seok KS, et al. Prevalence and diversity of microbes in the amniotic fluid, the fetal inflammatory response, and pregnancy outcome in women with preterm pre-labor rupture of membranes. Am J Reprod Immunol. 2010;64:38\u201357.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Cobo T, Kacerovsky M, Palacio M, Hornychova H, Hougaard DM, Skogstrand K, et al. A prediction model of histological chorioamnionitis and funisitis in preterm prelabor rupture of membranes: analyses of multiple proteins in the amniotic fluid. J Matern Fetal Neonatal Med. 2012;25:1995\u20132001.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Elimian A, Verma U, Beneck D, Cipriano R, Visintainer P, Tejani N. Histologic chorioamnionitis, antenatal steroids, and perinatal outcomes. Obstet Gynecol. 2000;96:333\u20136.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Aviram A, Quaglietta P, Warshafsky C, Zaltz A, Weiner E, Melamed N, et al. Utility of ultrasound assessment in management of pregnancies with preterm prelabor rupture of membranes. Ultrasound Obstet Gynecol. 2020;55:806\u201314.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kim CJ, Romero R, Chaemsaithong P, Chaiyasit N, Yoon BH, Kim YM. Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance. Am J Obstet Gynecol. 2015;213:S29\u201352.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

DiGiulio DB, Romero R, Amogan HP, Kusanovic JP, Bik EM, Gotsch F, et al. Microbial prevalence, diversity and abundance in amniotic fluid during preterm labor: a molecular and culture-based investigation. PLoS ONE. 2008;3:e3056.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Goldenberg RL, Hauth JC, Andrews WW. Intrauterine infection and preterm delivery. N Engl J Med. 2000;342:1500\u20137.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Oh KJ, Romero R, Park JY, Lee J, Conde-Agudelo A, Hong JS, et al. Evidence that antibiotic administration is effective in the treatment of a subset of patients with intra-amniotic infection\/inflammation presenting with cervical insufficiency. Am J Obstet Gynecol. 2019;221:140.e1\u2013.e18.<\/p>\n

Yoon BH, Romero R, Park JY, Oh KJ, Lee J, Conde-Agudelo A, et al. Antibiotic administration can eradicate intra-amniotic infection or intra-amniotic inflammation in a subset of patients with preterm labor and intact membranes. Am J Obstet Gynecol. 2019;221:142.e1\u2013.e22.<\/p>\n

Kacerovsky M, Romero R, Stepan M, Stranik J, Maly J, Pliskova L, et al. Antibiotic administration reduces the rate of intraamniotic inflammation in preterm prelabor rupture of the membranes. Am J Obstet Gynecol. 2020;223:e1141\u201320.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Subramaniam A, Abramovici A, Andrews WW, Tita AT. Antimicrobials for preterm birth prevention: an overview. Infect Dis Obstet Gynecol. 2012;2012:157159.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

van den Broek NR, White SA, Goodall M, Ntonya C, Kayira E, Kafulafula G, et al. The APPLe study: a randomized, community-based, placebo-controlled trial of Azithromycin for the prevention of preterm birth, with meta-analysis. PLoS Med. 2009;6:e1000191.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Gravett MG, Adams KM, Sadowsky DW, Grosvenor AR, Witkin SS, Axthelm MK, et al. Immunomodulators plus antibiotics delay preterm delivery after experimental intraamniotic infection in a nonhuman primate model. Am J Obstet Gynecol. 2007;197:e5181\u20138.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Been JV, Lievense S, Zimmermann LJ, Kramer BW, Wolfs TG. Chorioamnionitis as a risk factor for necrotizing enterocolitis: a systematic review and meta-analysis. J Pediatr. 2013;162:236\u201342.e2.<\/p>\n

Pappas A, Kendrick DE, Shankaran S, Stoll BJ, Bell EF, Laptook AR, et al. Chorioamnionitis and early childhood outcomes among extremely low-gestational-age neonates. JAMA Pediatr. 2014;168:137\u201347.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Shatrov JG, Birch SCM, Lam LT, Quinlivan JA, McIntyre S, Mendz GL. Chorioamnionitis and cerebral palsy: a meta-analysis. Obstet Gynecol. 2010;116:387\u201392.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Speer CP. Inflammation and bronchopulmonary dysplasia: a continuing story. Semin Fetal Neonatal Med. 2006;11:354\u201362.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wu YW, Colford JM. Jr. Chorioamnionitis as a risk factor for cerebral palsy: A meta-analysis. JAMA. 2000;284:1417\u201324.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Liu PC, Hung YL, Shen CM, Chen PC, Hsieh WS. Histological chorioamnionitis and its impact on respiratory outcome in very-low-birth-weight preterm infants. Pediatr Neonatol. 2021;62:258\u201364.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Jain VG, Kline JE, He L, Kline-Fath BM, Altaye M, Muglia LJ, et al. Acute histologic chorioamnionitis independently and directly increases the risk for brain abnormalities seen on magnetic resonance imaging in very preterm infants. Am J Obstet Gynecol. 2022;227:e6231\u201313.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Duan J, Xu F, Zhu C, Wang J, Zhang X, Xu Y, et al. Histological chorioamnionitis and pathological stages on very preterm infant outcomes. Histopathology. 2024.<\/p>\n

Salas AA, Faye-Petersen OM, Sims B, Peralta-Carcelen M, Reilly SD, McGwin G Jr., et al. Histological characteristics of the fetal inflammatory response associated with neurodevelopmental impairment and death in extremely preterm infants. J Pediatr. 2013;163:652\u2013e71.<\/p>\n

Park CW, Moon KC, Park JS, Jun JK, Romero R, Yoon BH. The involvement of human Amnion in histologic chorioamnionitis is an indicator that a fetal and an intra-amniotic inflammatory response is more likely and severe: clinical implications. Placenta. 2009;30:56\u201361.<\/p>\n

Yamada N, Sato Y, Moriguchi-Goto S, Yamashita A, Kodama Y, Sameshima H, et al. Histological severity of fetal inflammation is useful in predicting neonatal outcome. Placenta. 2015;36:1490\u20133.<\/p>\n

Shi H, Sun L, Wang Z, Zhang A, Cao H, Zhao W, et al. Non-invasive prediction of histologic chorioamnionitis using maternal serum markers in women with preterm prelabour rupture of membranes. Am J Reprod Immunol. 2022;88:e13594.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Balciuniene G, Kvederaite-Budre G, Gulbiniene V, Dumalakiene I, Viliene R, Pilypiene I, et al. Neutrophil-lymphocyte ratio for the prediction of histological chorioamnionitis in cases of preterm premature rupture of membranes: a case-control study. BMC Pregnancy Childbirth. 2021;21:656.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Cho HY, Jung I, Kwon JY, Kim SJ, Park YW, Kim YH. The delta neutrophil index as a predictive marker of histological chorioamnionitis in patients with preterm premature rupture of membranes: A retrospective study. PLoS ONE. 2017;12:e0173382.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ma Y, Xu Y, Jiang L, Shao X. Application of a prediction model based on the laboratory index score in prelabor rupture of membranes with histologic chorioamnionitis during late pregnancy. Med Sci Monit. 2020;26:e924756.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Asadi N, Faraji A, Keshavarzi A, Akbarzadeh-Jahromi M, Yoosefi S. Predictive value of procalcitonin, C-reactive protein, and white blood cells for chorioamnionitis among women with preterm premature rupture of membranes. Int J Gynaecol Obstet. 2019;147:83\u20138.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Dal Y, Karag\u00fcn \u015e, Akku\u015f F, \u00c7olak H, Aytan H, Co\u015fkun A. In premature rupture of membranes, maternal serum delta neutrophil index May be a predictive factor for histological chorioamnionitis and affect fetal inflammatory markers: A retrospective cross-sectional study. Am J Reprod Immunol. 2024;91:e13823.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang J, Zhu QW, Cheng XY, Liu JY, Zhang LL, Tao YM, et al. Assessment efficacy of neutrophil-lymphocyte ratio and monocyte-lymphocyte ratio in preeclampsia. J Reprod Immunol. 2019;132:29\u201334.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hessami K, Tabrizi R, Homayoon N, Hashemi A, Heydari ST, Pourhoseini SA. Gestational diabetes mellitus and inflammatory biomarkers of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio: a systematic review and meta-analysis. Biomarkers. 2021;26:491\u20138.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang X, Wu Z, Zhang Z, Jiang Z. Prognostic and clinicopathological value of systemic immune-inflammation index in patients with osteosarcoma: a meta-analysis. Front Immunol. 2024;15:1416068.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhang H, Lin J, Huang Y, Chen Y. The systemic Immune-Inflammation index as an independent predictor of survival in patients with locally advanced esophageal squamous cell carcinoma undergoing neoadjuvant radiotherapy. J Inflamm Res. 2024;17:4575\u201386.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Redline RW. Classification of placental lesions. Am J Obstet Gynecol. 2015;213:S21\u20138.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Torricelli M, Voltolini C, Toti P, Vellucci FL, Conti N, Cannoni A, et al. Histologic chorioamnionitis: different histologic features at different gestational ages. J Matern Fetal Neonatal Med. 2014;27:910\u20133.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Guo X, Wang Y, Obore N, Qian W, Yu H. Research hotspots and trends in the diagnosis of chorioamnionitis: based on bibliometric analysis from 2010 to 2022. Am J Perinatol. 2023.<\/p>\n

Lee JH, Park CW, Moon KC, Park JS, Jun JK. Neutrophil to lymphocyte ratio in maternal blood: a clue to suspect amnionitis. J Clin Med. 2021;10:2673.<\/p>\n

Tang MQ, Xie J, Rao LM, Kan YJ, Luo P, Qing LS. Advances in aptamer-based sensing assays for C-reactive protein. Anal Bioanal Chem. 2022;414:867\u201384.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ansar W, Ghosh S. C-reactive protein and the biology of disease. Immunol Res. 2013;56:131\u201342.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Bakar RZ, K\u00f6ro\u011flu N, Turkgeldi LS, Tola EN, Cetin BA, Gedikbasi A. Maternal serum procalcitonin levels in prediction of chorioamnionitis in women with preterm premature rupture of membranes. Arch Med Sci. 2021;17:694\u20139.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kim SA, Park KH, Lee SM. Non-Invasive prediction of histologic chorioamnionitis in women with preterm premature rupture of membranes. Yonsei Med J. 2016;57:461\u20138.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wondie WT, Legesse BT, Mekonnen GB, Degaga GT, Zemariam AB, Gedefaw GD, et al. Incidence and predictors of respiratory distress syndrome among low birth weight neonates in the first seven days in Northwest Ethiopia comprehensive specialized Hospitals, 2023: A retrospective follow-up study. BMJ Open. 2023;13:e079063.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Liu J, Yang N, Liu Y. High-risk factors of respiratory distress syndrome in term neonates: A retrospective Case-control study. Balkan Med J. 2014;31:64\u20138.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Roberts D, Brown J, Medley N, Dalziel SR. Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth. Cochrane Database Syst Rev. 2017;3:Cd004454.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Effect of corticosteroids for fetal maturation on perinatal outcomes. NIH consensus development panel on the effect of corticosteroids for fetal maturation on perinatal outcomes. JAMA. 1995;273:413\u20138.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Jobe AH. Miracle extremely low birth weight neonates: examples of developmental plasticity. Obstet Gynecol. 2010;116:1184\u201390.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Speer CP. Neonatal respiratory distress syndrome: an inflammatory disease? Neonatology. 2011;99:316\u20139.<\/p>\n

Seehase M, Collins JJ, Kuypers E, Jellema RK, Ophelders DR, Ospina OL, et al. New surfactant with SP-B and C analogs gives survival benefit after inactivation in preterm lambs. PLoS ONE. 2012;7:e47631.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Liu WL, Zhou Y, Zhang C, Chen J, Yin XF, Zhou FX, et al. Relationship between chorioamnionitis or funisitis and lung injury among preterm infants: meta-analysis involved 16 observational studies with 68,397 participants. BMC Pediatr. 2024;24:157.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Villar J, Restrepo-M\u00e9ndez MC, McGready R, Barros FC, Victora CG, Munim S, et al. Association between Preterm-Birth phenotypes and differential Morbidity, Growth, and neurodevelopment at age 2 years: results from the INTERBIO-21st newborn study. JAMA Pediatr. 2021;175:483\u201393.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Barros FC, Papageorghiou AT, Victora CG, Noble JA, Pang R, Iams J, et al. The distribution of clinical phenotypes of preterm birth syndrome: implications for prevention. JAMA Pediatr. 2015;169:220\u20139.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Frenquelli R, Ratcliff M, Villar de Onis J, Fernandes M, Barros FC, Hirst JE, et al. Complex perinatal syndromes affecting early human growth and development: issues to consider to understand their aetiology and postnatal effects. Front Neurosci. 2022;16:856886.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Romero R, Dey SK, Fisher SJ. Preterm labor: one syndrome, many causes. Science. 2014;345:760\u20135.<\/p>\n

CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Villar J, Cavoretto PI, Barros FC, Romero R, Papageorghiou AT, Kennedy SH. Etiologically based functional taxonomy of the preterm birth syndrome. Clin Perinatol. 2024;51:475\u201395.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n","protected":false},"excerpt":{"rendered":"Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008;371:75\u201384. PubMed\u00a0 PubMed…\n","protected":false},"author":2,"featured_media":141553,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[87460,28048,163,85,46,44154,87462,87463,44153,87461],"class_list":["post-141552","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-acute-histologic-chorioamnionitis","tag-gynecology","tag-health","tag-il","tag-israel","tag-maternal-and-child-health","tag-neonatal-respiratory-distress-syndrome","tag-pathological-stages","tag-reproductive-medicine","tag-systemic-immune-inflammation-index"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/141552","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=141552"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/141552\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/141553"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=141552"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=141552"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=141552"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}