{"id":150149,"date":"2025-11-24T11:22:09","date_gmt":"2025-11-24T11:22:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/150149\/"},"modified":"2025-11-24T11:22:09","modified_gmt":"2025-11-24T11:22:09","slug":"use-of-quasi-experimental-studies-to-evaluate-causal-effects-of-public-health-interventions-in-portugal-a-scoping-review-bmc-medical-research-methodology","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/150149\/","title":{"rendered":"Use of quasi-experimental studies to evaluate causal effects of public health interventions in Portugal: a scoping review | BMC Medical Research Methodology"},"content":{"rendered":"

B\u00e4rnighausen T, R\u00f8ttingen JA, Rockers P, Shemilt I, Tugwell P. Quasi-experimental study designs series\u2014paper 1: introduction: two historical lineages. J Clin Epidemiol. 2017;89:4\u201311.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ogilvie D, Adams J, Bauman A, et al. Using natural experimental studies to guide public health action: turning the evidence-based medicine paradigm on its head. J Epidemiol Community Health. 2019. https:\/\/doi.org\/10.1136\/jech-2019-213085<\/a>.<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Reeves BC, Wells GA, Waddington H. Quasi-experimental study designs series\u2014paper 5: a checklist for classifying studies evaluating the effects on health interventions\u2014a taxonomy without labels. J Clin Epidemiol. 2017;89:30\u201342.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Glanville J, Eyers J, Jones AM, et al. Quasi-experimental study designs series\u2014paper 8: identifying quasi-experimental studies to inform systematic reviews. J Clin Epidemiol. 2017;89:67\u201376.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Basu S, Meghani A, Siddiqi A. Evaluating the health impact of large-scale public policy changes: classical and novel approaches. Annu Rev Public Health. 2017;38:351\u201370.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Abreu D, Pinto F, Matias-Dias C, Sousa P. Trends of case-fatality rate by acute coronary syndrome in Portugal: impact of a fast track to the coronary unit. JRSM Cardiovasc Dis. 2019;8:204800401985195.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kislaya I, Rodrigues AP, Sousa-Uva M, et al. Indirect effect of 7-valent and 13-valent Pneumococcal conjugated vaccines on Pneumococcal pneumonia hospitalizations in elderly. PLoS ONE. 2019;14(1):65\u201374.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Torres AR, Rodrigues AP, Sousa-Uva M, et al. Impact of stringent non-pharmaceutical interventions applied during the second and third COVID-19 epidemic waves in Portugal, 9 November 2020 to 10 February 2021: an ecological study. Eurosurveillance. 2022;27(3):1\u201312.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Tricco AC, Lillie E, Zarin W, et al. Preferred reporting items for systematic reviews and Meta-Analyses extension for scoping reviews (PRISMA-ScR) checklist SECTION. Ann Intern Med. 2018;169(7):11\u20132.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Leite A, Kislaya I, Machado A, Aguiar P, Nunes B, Matias Dias C. Use of quasi-experimental studies to evaluate causal effects of public health interventions in portugal: a scoping review protocol. 2022. Available from: osf.io\/zex3v<\/a>. Cited 2022 Sep 26.<\/p>\n

Open Science Framework (OSF). Available from: https:\/\/doi.org\/10.17605\/OSF.IO\/G9KVE<\/a>. cited 2022 Sep 26.<\/p>\n

Instituto Nacional de Sa\u00fade Doutor Ricardo Jorge. Boletim Epidemiol\u00f3gico Observa\u00e7\u00f5es [Internet]. [cited 2022 Sep 26]. Available from: https:\/\/www.insa.min-saude.pt\/category\/informacao-e-cultura-cientifica\/publicacoes\/boletim-epidemiologico-observacoes\/<\/a><\/p>\n

Bond, University. Institute for evidence-based healthcare. SR-Accelerator. Available from: https:\/\/sr-accelerator.com\/#\/<\/a>. Cited 2024 Mar 21. <\/p>\n

Rayyan. \u2013 Intelligent Systematic Review – Rayyan. Available from: https:\/\/www.rayyan.ai\/<\/a>. Cited 2022 Sep 26. <\/p>\n

Waddington H, Aloe AM, Becker BJ, et al. Quasi-experimental study designs series\u2014paper 6: risk of bias assessment. J Clin Epidemiol. 2017;89:43\u201352.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

de Vocht F, Katikireddi SV, McQuire C, Tilling K, Hickman M, Craig P. Conceptualising natural and quasi experiments in public health. BMC Med Res Methodol. 2021;21(1):1\u20138.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Haddaway NR, Page MJ, Pritchard CC, McGuinness LA. PRISMA2020: an R package and Shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and open synthesis. Campbell Syst Rev. 2022;18(2):1\u201312.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Abreu D, Sousa P, Matias-Dias C, Pinto FJ. Longitudinal impact of the smoking ban legislation in acute coronary syndrome admissions. BioMed Res Int. 2017. https:\/\/doi.org\/10.1155\/2017\/6956941<\/a>.<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Abreu D, Sousa P, Matias-Dias C, Pinto FJ. Cardiovascular disease and high blood pressure trend analyses from 2002 to 2016: after the implementation of a salt reduction strategy. BMC Public Health. 2018;18(1):722.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Abreu D, Sousa P, Matias-Dias C, Pinto F. Impact of public health initiatives on acute coronary syndrome fatality rates in Portugal. Rev Port Cardiol. 2020;39(1):27\u201334.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Adam C, Raschzok A. Cannabis policy and the uptake of treatment for cannabis-related problems. Drug Alcohol Rev. 2017;36(2):171\u20137.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Aiken ARA, Starling JE, Gomperts R, Scott JG, Aiken CE. Demand for self-managed online telemedicine abortion in eight European countries during the COVID-19 pandemic: a regression discontinuity analysis. BMJ Sex Reprod Health. 2021;47(4):238\u201345.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Bellerba F, Bardeck N, Boehm M, et al. SARS-CoV-2 trends in Italy, Germany and Portugal and school opening during the period of Omicron variant dominance: a quasi experimental study in the EuCARE project. Int J Infect Dis. 2024. https:\/\/doi.org\/10.1016\/j.ijid.2023.11.002<\/a>.<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Benedetti E, Resce G, Brunori P, Molinaro S. Cannabis policy changes and adolescent cannabis use: evidence from Europe. Int J Environ Res Public Health. 2021. https:\/\/doi.org\/10.3390\/ijerph18105174<\/a>.<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Dimitrovov\u00e1 K, Perelman J, Serrano-Alarc\u00f3n M. Effect of a national primary care reform on avoidable hospital admissions (2000\u20132015): a difference-in-difference analysis. Soc Sci Med. 2020;252:112908.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Fernandes OB, Lopes S, Marques AP, Moita B, Sarmento J, Santana R. Local health units in Portugal: the influence of chronic conditions on inpatient readmissions. Port J Public Heal. 2020;37(2\u20133):91\u20139.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Gon\u00e7alves J, Pereira Dos Santos J. Brown sugar, how come you taste so good? The impact of a soda tax on prices and consumption. Soc Sci Med. 2020;264:113332.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hoffman SJ, Poirier MJP, Van Rogers S, Baral P, Sritharan L. Impact of the WHO framework convention on tobacco control on global cigarette consumption: Quasi-experimental evaluations using interrupted time series analysis and in-sample forecast event modelling. BMJ. 2019;365.<\/p>\n

Leit\u00e3o C, Silva S, Roquette R, Uva M, Baltazar N. Ser\u00e1 Que Os Planos de conting\u00eancia Para Ondas de Calor reduzem a Mortalidade associada Ao Calor ? Um Estudo Da diferen\u00e7a-das-diferen\u00e7as Em Portugal (Do heat contingency plans reduce heat related deaths? A difference-in-difference study in Portugal). Obs Bol Epidemiol\u00f3gico – Inst Nac Sa\u00fade Dr Ricardo Jorge. 2020;26:4\u20138.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lopes S, Fernandes \u00d3B, Marques AP, Moita B, Sarmento J, Santana R. Can vertical integration reduce hospital readmissions? A difference-in-differences approach. Med Care. 2017;55(5):506\u201313.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Pereira AM, Pereira RM, Dos Santos JP. For whom the bell tolls: road safety effects of tolls ouncongested SCUT highways in Portugal. J Infrastructure Policy Dev. 2020;4(2):287\u2013305.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Pinto D, Silva A, Heleno B, Rodrigues DS, Santos I, Caetano PA. Effect of European medicines agency\u2019s regulatory measures on nimesulide utilization in Portugal. Pharmacoepidemiol Drug Saf. 2018;27(6):630\u20137.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Pinto D, Silva A, Heleno B, Rodrigues DS, Santos I, Caetano PA. Effect of European medicines agency\u2019s restrictions on Trimetazidine utilization in Portugal. Pharmacoepidemiol Drug Saf. 2018;27(9):962\u20138.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ramos P, Almeida A. The impact of an increase in user costs on the demand for emergency services: the case of Portuguese hospitals. Health Econ. 2016;25(11):1372\u201388.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ricoca Peixoto V, Vieira A, Aguiar P, Carvalho C, Rhys Thomas D, Abrantes A. Initial assessment of the impact of the emergency state lockdown measures on the 1st wave of the COVID-19 epidemic in Portugal. Acta Med Port. 2020;33(11):733\u201341.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

S\u00e1nchez R. Does a mandatory reduction of standard working hours improve employees\u2019. health status? Ind Relat. 2017;56(1):3\u201339.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Sassano M, Mariani M, Pastorino R, Ricciardi W, La Vecchia C, Boccia S. Association of national smoke-free policies with per-capita cigarette consumption and acute myocardial infarction mortality in Europe. J Epidemiol Community Health. 2024. https:\/\/doi.org\/10.1136\/jech-2023-220746<\/a>.<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Torres AR, Rodrigues AP, Sousa-Uva M et al. Impact of stringent non-pharmaceutical interventions applied during the second and third COVID-19 epidemic waves in Portugal, 9 November 2020 to 10 February 2021: an ecological study. Euro Surveill. 2022;27(23).<\/p>\n

Torres AR, Silva S, Kislaya I, et al. Impact of lifting mask mandates on COVID-19 incidence and mortality in portugal: an ecological study. Acta Med Port. 2023;36(10):661\u20139.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Vaz S, Ramos P. Where did civil servants go? The effect of an increase in public co-payments on double insured patients. Health Econ Rev. 2016;6(1):16.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Matthay EC, Glymour MM. Causal inference challenges and new directions for epidemiologic research on the health effects of social policies. Curr Epidemiol Rep. 2022;9(1):22\u201337.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Jandoc R, Burden AM, Mamdani M, L\u00e9vesque LE, Cadarette SM. Interrupted time series analysis in drug utilization research is increasing: systematic review and recommendations. J Clin Epidemiol. 2015;68(8):950\u20136.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hilton Boon M, Craig P, Thomson H, Campbell M, Moore L. Regres Discontinuity Designs Health: Syst Rev Epidemiol. 2021;32(1):87\u201393.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kennedy-Shaffer L. Quasi-experimental methods for pharmacoepidemiology: difference-in-differences and synthetic control methods with case studies for vaccine evaluation. Am J Epidemiol. 2024;193(7):1050\u20138.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hategeka C, Ruton H, Karamouzian M, Lynd LD, Law MR. Use of interrupted time series methods in the evaluation of health system quality improvement interventions: A methodological systematic review. BMJ Glob Heal. 2020;5(10):1\u201313.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ewusie JE, Soobiah C, Blondal E, Beyene J, Thabane L, Hamid JS. Methods, applications and challenges in the analysis of interrupted time series data: A scoping review. J Multidiscip Healthc. 2020;13:411\u201323.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Albers PN, Rinaldi C, Brown H, et al. Natural experiments for the evaluation of place-based public health interventions: a methodology scoping review. Front Public Health. 2023. https:\/\/doi.org\/10.3389\/fpubh.2023.1192055<\/a>.<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Akter S, Islam MR, Rahman MM, et al. Evaluation of population-level tobacco control interventions and health outcomes: a systematic review and meta-analysis. JAMA Netw Open. 2023;6(7):E2322341.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Moscoe E, Bor J, B\u00e4rnighausen T. Regression discontinuity designs are underutilized in medicine, epidemiology, and public health: a review of current and best practice. J Clin Epidemiol. 2015;68(2):132\u201343.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang G, Hamad R, White JS. Advances in difference-in-differences methods for policy evaluation research. Epidemiology. 2024;35(5):628\u201337.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Bernal JL, Cummins S, Gasparrini A. Interrupted time series regression for the evaluation of public health interventions: a tutorial. Int J Epidemiol. 2017;46(1):348\u201355.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rothbard S, Etheridge JC, Murray EJ. A tutorial on applying the difference-in-differences method to health data. Curr Epidemiol Rep. 2023;11(2):85\u201395.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Turner SL, Karahalios A, Forbes AB, et al. Design characteristics and statistical methods used in interrupted time series studies evaluating public health interventions: a review. J Clin Epidemiol. 2020;122:1\u201311.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Korevaar E, Karahalios A, Turner SL, et al. Methodological systematic review recommends improvements to conduct and reporting when meta-analyzing interrupted time series studies. J Clin Epidemiol. 2022;145:55\u201369.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hudson J, Fielding S, Ramsay CR. Methodology and reporting characteristics of studies using interrupted time series design in healthcare. BMC Med Res Methodol. 2019;19(1):1\u20137.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Leonard SA, Panelli DM. Quasi-experimental study designs can inform pandemic effects on nutrition and weight gain in pregnancy. Am J Clin Nutr. 2023;117(2):216\u20137.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lopes S, Soares P, Santos Sousa J, Rocha JV, Boto P, Santana R. Effect of the COVID-19 pandemic on the frequency of emergency department visits in Portugal: an interrupted time series analysis until July 2021. JACEP Open. 2023;4(1):e12864.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Domingues M, Torre C, Guerreiro JP, et al. COVID-19 pandemic and the quality of antibiotic use in primary care: an interrupted time-series study. Int J Qual Health Care. 2023;35(2):mzad014.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Almeida D, Rodrigues AT, Guerreiro JP, et al. COVID-19 pandemic and the consumption of self-care products for pediculosis capitis in Portugal: an interrupted time-series analysis. Parasitol Res. 2024;123(6):235.<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hanquet G, Valenciano M, Simondon F, Moren A. Vaccine effects and impact of vaccination programmes in post-licensure studies. Vaccine. 2013;31(48):5634\u201342.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Su SY. Nationwide mammographic screening and breast cancer mortality in Taiwan: an interrupted time-series analysis. Breast Cancer. 2022;29(2):336\u201342.<\/p>\n

PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n","protected":false},"excerpt":{"rendered":"B\u00e4rnighausen T, R\u00f8ttingen JA, Rockers P, Shemilt I, Tugwell P. Quasi-experimental study designs series\u2014paper 1: introduction: two historical…\n","protected":false},"author":2,"featured_media":150150,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[114,91711,34967,85,46,2409,546,91712,35696,35697,35695],"class_list":["post-150149","post","type-post","status-publish","format-standard","has-post-thumbnail","category-business","tag-business","tag-causal-effects","tag-health-sciences","tag-il","tag-israel","tag-medicine","tag-public-health","tag-quasi-experimental-studies","tag-statistical-theory-and-methods","tag-statistics-for-life-sciences","tag-theory-of-medicine-bioethics"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/150149","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=150149"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/150149\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/150150"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=150149"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=150149"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=150149"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}