{"id":202809,"date":"2025-12-25T05:42:33","date_gmt":"2025-12-25T05:42:33","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/202809\/"},"modified":"2025-12-25T05:42:33","modified_gmt":"2025-12-25T05:42:33","slug":"astroglial-kappa-opioid-receptor-mediated-reduction-of-glutamate-exchanger-xct-in-the-prelimbic-cortex-underlies-chronic-stress-induced-depressive-like-behaviors","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/202809\/","title":{"rendered":"Astroglial kappa opioid receptor-mediated reduction of glutamate exchanger xCT in the prelimbic cortex underlies chronic stress-induced depressive-like behaviors"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Monroe SM, Harkness KL. Major depression and its recurrences: life course matters. 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