{"id":325321,"date":"2026-03-06T17:42:12","date_gmt":"2026-03-06T17:42:12","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/325321\/"},"modified":"2026-03-06T17:42:12","modified_gmt":"2026-03-06T17:42:12","slug":"study-reveals-cannabis-compounds-reduce-threat-of-fatty-liver-disease-health","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/325321\/","title":{"rendered":"Study reveals cannabis compounds reduce threat of fatty liver disease | Health"},"content":{"rendered":"

Cannabis compounds<\/a> reduces the threat of potentially deadly fatty liver disease, according to new research.<\/p>\n

Naturally occurring chemicals found in the drug can “significantly” cut liver fat and cholesterol levels and improve the body’s ability to efficiently process energy, say scientists.<\/p>\n

The study reveals that two key cannabis compounds<\/a> work by creating a backup energy reserve in the liver and restoring the activity of cellular “cleaning crews” to break down harmful waste.<\/p>\n

Researchers in Israel say their findings, published in the British Journal of Pharmacology<\/a>, highlight a new, plant-based path for treating the world\u2019s most common chronic liver disorder.<\/p>\n

The study suggests that Cannabidiol<\/a> (CBD) and Cannabigerol (CBG), which are non-psychoactive and do not cause a high, can improve liver health by changing how the vital organ manages energy and cleans itself.<\/p>\n

\"Cannabis<\/p>\n

Professor Joseph Tam and research team. (Tom Barnea via SWNS)<\/p>\n

By Talker<\/p>\n

Metabolic dysfunction-associated steatotic liver disease, or MASLD, is currently the world’s most common chronic liver disorder.<\/p>\n

It affects around one-in-three adults and is closely linked to obesity, high blood pressure, and insulin resistance.<\/p>\n

While lifestyle factors such as diet and exercise are important, they can be hard to maintain, and there are few approved medicines currently available for the condition.<\/p>\n

Study leader Professor Joseph Tam said: “Our findings identify a new mechanism by which CBD<\/a> and CBG enhance hepatic energy and lysosomal function.<\/p>\n

“This dual metabolic remodelling contributes to improved liver lipid handling and highlights these compounds as promising therapeutic agents for MASLD”.<\/p>\n

His team used advanced tools to show that CBD<\/a> and CBG do more than just reduce fat.<\/p>\n

They found the compounds actually help the liver function better internally through a unique process of “metabolic remodeling”.<\/p>\n

\"pexels-kindelmedia-7667738\"<\/p>\n

(Photo by Kindel Media via Pexels)<\/p>\n

<\/p>\n


\n \"How
\n <\/a><\/p>\n

Tam, from the Hebrew University of Jerusalem<\/a>, said: “One of the most important findings was the impact on the liver’s energy reserves.<\/p>\n

“These compounds increase levels of phosphocreatine, which acts like a backup battery to help the liver stay healthy under the stress caused by a high-fat diet.<\/p>\n

“This is a new discovery, as the liver does not usually rely heavily on this specific energy system.”<\/p>\n

The researchers also found that CBD<\/a> and CBG restore the activity of cathepsins – enzymes that act like a “cleaning crew” within the cell’s recycling centres, known as lysosomes.<\/p>\n

Tam said: “By getting this cleaning crew back to work, the liver is better able to break down and clear out harmful fats and waste.”<\/p>\n

The researchers also found that both treatments significantly reduced harmful lipids – such as triglycerides and ceramides.<\/p>\n

Ceramides are particularly dangerous because they are known to contribute to insulin resistance and liver inflammation.<\/p>\n

The study showed that while both compounds were effective, they each provided slightly different benefits for metabolic health.<\/p>\n

\"Cannabis<\/p>\n

Professor Joseph Tam is the lead author of the study. (Tom Barnea via SWNS)<\/p>\n

By Talker<\/p>\n

Tam said: “Both CBD and CBG were able to normalize blood sugar levels and improve how the body clears glucose.<\/p>\n

“However, CBG appeared to have a more pronounced effect on certain metrics.<\/p>\n

“It significantly reduced body fat mass and improved insulin sensitivity more robustly than CBD.<\/p>\n

“CBG was also particularly effective at lowering total cholesterol and ‘bad’ LDL cholesterol levels.”<\/p>\n

While the results are encouraging, the researchers say further studies are needed to understand how the findings can best be applied to human patients.<\/p>\n

Tam added: “This study opens a new path for using plant-based compounds to treat metabolic diseases by focusing on how cells manage energy and waste.”<\/p>\n","protected":false},"excerpt":{"rendered":"Cannabis compounds reduces the threat of potentially deadly fatty liver disease, according to new research. Naturally occurring chemicals…\n","protected":false},"author":2,"featured_media":325322,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[54493,161050,5201,3870,3858,3862,24613,2639,163,4454,85,9716,46,10108,81002,3865,58572,39020],"class_list":{"0":"post-325321","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-cannabidiol","9":"tag-ceramide","10":"tag-cholesterol","11":"tag-chronic-condition","12":"tag-clinical-medicine","13":"tag-diseases-and-disorders","14":"tag-fat","15":"tag-fatty-liver-disease","16":"tag-health","17":"tag-human-diseases-and-disorders","18":"tag-il","19":"tag-insulin-resistance","20":"tag-israel","21":"tag-liver","22":"tag-low-density-lipoprotein","23":"tag-medical-specialties","24":"tag-metabolic-dysfunction-associated-steatotic-liver-disease","25":"tag-stephen-beech"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/325321","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=325321"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/325321\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/325322"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=325321"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=325321"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=325321"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}