The Lancet Regional Health: Americas<\/a>.\u00a0<\/p>\n\u201cAs our population ages, more patients over 80 are being diagnosed with early-stage lung cancer, yet they are often not\u00a0considered for\u00a0surgery,\u201d said lead study author\u00a0Raja\u00a0M.\u00a0Flores, MD, Chair of\u00a0the Department of\u00a0Thoracic Surgery at Mount Sinai\u00a0Health System. \u201cOur findings show that when patients are carefully selected based on their overall health,\u00a0not just their age,\u00a0they can tolerate surgery well and experience excellent long-term outcomes.\u201d\u00a0<\/p>\n
\u201cOur\u00a0study highlights the importance of making sure all patients are evaluated based on their overall health, not just their age,\u201d said study author\u00a0Emanuela\u00a0Taioli, MD, PhD, Director of the Institute for Translational Epidemiology at the Icahn School of Medicine. \u201cWe must\u00a0ensure that effective treatments are available to everyone who can\u00a0benefit\u00a0from them. Older adults are often left out of clinical decisions, but our findings show they should have equal access to care that can improve survival and quality of life.\u201d\u00a0<\/p>\n
Background\u00a0and Study Methods\u00a0<\/p>\n
Patients aged 80 years and older are increasingly being diagnosed with early-stage lung cancer as the life expectancy of the population expands. These patients are typically excluded from screening programs and clinical trials, though, due to age-related concerns of added risks.<\/p>\n
Researchers assessed\u00a0884 patients with stage IA NSCLC from the Mount Sinai Health System\u00a0in the prospective Initiative for Early Lung Cancer Research on Treatment (IELCART) study. The clinical presentation, type of surgery, postoperative outcomes, and survival outcomes were compared for the octogenarians (12.9%) vs younger patients in the cohort.\u00a0<\/p>\n
Key Findings\u00a0<\/p>\n
Octogenarians with NSCLC in the IELCART study had similar rates of comorbidities as younger patients but were more likely to receive sublobar resections (78.9% vs 62.4%; P\u00a0= .030). Patients 80 years and older had higher complication rates than younger patients (40% vs 22%;\u00a0P\u00a0< .0001), especially cardiovascular complications. Both intensive care unit admissions and readmissions were a bit more common in the older patient group.<\/p>\n
Physical and mental health declined\u00a0at 2 months in both age groups, but improved at 1 year after surgery, with no significant differences observed.\u00a0<\/p>\n
At 5 years, overall survival rates were similar between the two age groups at 84.2% for octogenarians and 87.3% for younger patients; lung cancer\u2013specific survival rates at 5 years were 94.4% in the older patient group and 94.5% in the younger patient group.\u00a0<\/p>\n
\u201cWe should treat the whole person, not just the number of years they have lived,\u201d Dr. Flores said. \u201cIf a patient is strong enough, surgery can save their life.\u201d\u00a0<\/p>\n
\u201cEarly detection and thoughtful treatment go hand in hand,\u201d said study author\u00a0Claudia Henschke,\u00a0PhD,\u00a0MD,\u00a0Professor of Diagnostic, Molecular and Interventional Radiology and Director of the Early Lung and Cardiac Action Program (ELCAP) at the Icahn School of Medicine at Mount Sinai. \u201cWhen lung cancer is found at an early stage, patients (even those over 80) can\u00a0benefit\u00a0from treatments that offer a real chance at\u00a0a\u00a0cure. This study shows that with the right\u00a0approach,\u00a0we can extend both life and quality of life for older adults.\u00a0Additionally,\u00a0screening guidelines should include patients who are over 80 years old based on these findings.\u201d\u00a0<\/p>\n
DISCLOSURE: This study was supported by the Simons Foundation. For full disclosures of the study authors, visit\u00a0thelancet.com<\/a>.\u00a0<\/p>\n
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Surgical treatment was found to be safe and demonstrate long-term quality-of-life benefits for carefully selected octogenarians with…\n","protected":false},"author":2,"featured_media":378105,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[163,85,46],"class_list":{"0":"post-378104","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-health","9":"tag-il","10":"tag-israel"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/378104","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=378104"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/378104\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/378105"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=378104"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=378104"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=378104"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}