{"id":395951,"date":"2026-04-16T22:22:07","date_gmt":"2026-04-16T22:22:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/395951\/"},"modified":"2026-04-16T22:22:07","modified_gmt":"2026-04-16T22:22:07","slug":"openai-starts-offering-a-biology-tuned-llm","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/395951\/","title":{"rendered":"OpenAI starts offering a biology-tuned LLM"},"content":{"rendered":"<p>To address LLMs\u2019 tendencies toward sycophancy and overenthusiasm, OpenAI says it has tuned the model to be more skeptical, so it\u2019s more likely to tell you when something is a bad drug target. There was a lot of talk about GPT-Rosalind\u2019s \u201creasoning\u201d and \u201cexpert-level\u201d abilities. We were told that the former was defined as being able to work through complex, multi-step processes, while the latter was derived from the model\u2019s performance on a handful of benchmarks.<\/p>\n<p>It\u2019s unclear whether OpenAI has tackled the hallucination issue that has plagued a variety of LLMs and can also strike when the systems are prompted to explain the steps the company took to reach its conclusions. Given past experience, it\u2019s likely we\u2019ll see a mix of glowing reports about unexpected connections the AI finds, as well as instances where it produces obviously erroneous suggestions.<\/p>\n<p>For the moment, however, the company is limiting access due to concerns about the model\u2019s potential for harmful outputs if asked to do something like optimize a virus\u2019s infectivity. Only US-based entities can apply to OpenAI\u2019s trusted access deployment structure at the moment, and the company will limit who can use it. A more limited Life Sciences Research Plugin will be made generally available.<\/p>\n<p>As noted above, a number of other companies have made science-focused agentic LLMs available, but those were much less focused than GPT-Rosalind, which is biology-specific. Until we start hearing reports on the effectiveness of this new model, it\u2019s difficult to evaluate whether this focus improves its utility.<\/p>\n","protected":false},"excerpt":{"rendered":"To address LLMs\u2019 tendencies toward sycophancy and overenthusiasm, OpenAI says it has tuned the model to be more&hellip;\n","protected":false},"author":2,"featured_media":395952,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[345,343,344,85,46,125],"class_list":{"0":"post-395951","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-artificial-intelligence","8":"tag-ai","9":"tag-artificial-intelligence","10":"tag-artificialintelligence","11":"tag-il","12":"tag-israel","13":"tag-technology"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/395951","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=395951"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/395951\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/395952"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=395951"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=395951"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=395951"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}