{"id":398068,"date":"2026-04-18T03:28:15","date_gmt":"2026-04-18T03:28:15","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/398068\/"},"modified":"2026-04-18T03:28:15","modified_gmt":"2026-04-18T03:28:15","slug":"wolbachia-driven-host-mirnas-mediate-arthropod-reproduction-in-a-wolbachia-density-dependent-manner","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/398068\/","title":{"rendered":"Wolbachia-driven host miRNAs mediate arthropod reproduction in a Wolbachia density-dependent manner"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Gotoh, T., Noda, H. &amp; Hong, X. Y. Wolbachia distribution and cytoplasmic incompatibility based on a survey of 42 spider mite species (Acari: Tetranychidae) in Japan. Heredity 91, 208\u2013216 (2003).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 1\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20distribution%20and%20cytoplasmic%20incompatibility%20based%20on%20a%20survey%20of%2042%20spider%20mite%20species%20%28Acari%3A%20Tetranychidae%29%20in%20Japan&amp;journal=Heredity&amp;volume=91&amp;pages=208-216&amp;publication_year=2003&amp;author=Gotoh%2CT&amp;author=Noda%2CH&amp;author=Hong%2CXY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR2\">Porter, J. &amp; Sullivan, W. The cellular lives of Wolbachia. Nat. Rev. Microbiol. 21, 750\u2013766 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 2\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20cellular%20lives%20of%20Wolbachia&amp;journal=Nat.%20Rev.%20Microbiol.&amp;volume=21&amp;pages=750-766&amp;publication_year=2023&amp;author=Porter%2CJ&amp;author=Sullivan%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR3\">Hilgenboecker, K., Hammerstein, P., Schlattmann, P., Telschow, A. &amp; Werren, J. H. How many species are infected with Wolbachia?-A statistical analysis of current data. FEMS Microbiol. Lett. 281, 215\u2013220 (2008).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 3\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=How%20many%20species%20are%20infected%20with%20Wolbachia%3F-A%20statistical%20analysis%20of%20current%20data&amp;journal=FEMS%20Microbiol.%20Lett.&amp;volume=281&amp;pages=215-220&amp;publication_year=2008&amp;author=Hilgenboecker%2CK&amp;author=Hammerstein%2CP&amp;author=Schlattmann%2CP&amp;author=Telschow%2CA&amp;author=Werren%2CJH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR4\">Ribeiro, P. et al. Pervasive horizontal transmission of Wolbachia in natural populations of closely related and widespread tropical skipper butterflies. BMC Microbiol. 25, 5 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 4\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Pervasive%20horizontal%20transmission%20of%20Wolbachia%20in%20natural%20populations%20of%20closely%20related%20and%20widespread%20tropical%20skipper%20butterflies&amp;journal=BMC%20Microbiol.&amp;volume=25&amp;publication_year=2025&amp;author=Ribeiro%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR5\">Werren, J. H., Baldo, L. &amp; Clark, M. E. Wolbachia: master manipulators of invertebrate biology. Nat. Rev. Microbiol. 6, 741\u2013751 (2008).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 5\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%3A%20master%20manipulators%20of%20invertebrate%20biology&amp;journal=Nat.%20Rev.%20Microbiol.&amp;volume=6&amp;pages=741-751&amp;publication_year=2008&amp;author=Werren%2CJH&amp;author=Baldo%2CL&amp;author=Clark%2CME\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR6\">Beckmann, J. F., Ronau, J. A. &amp; Hochstrasser, M. A. deubiquitylating enzyme induces cytoplasmic incompatibility. Nat. Microbiol. 2, 17007 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 6\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=deubiquitylating%20enzyme%20induces%20cytoplasmic%20incompatibility&amp;journal=Nat.%20Microbiol.&amp;volume=2&amp;publication_year=2017&amp;author=Beckmann%2CJF&amp;author=Ronau%2CJA&amp;author=Hochstrasser%2CMA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR7\">Shropshire, J. D., Leigh, B. &amp; Bordenstein, S. R. Symbiont-mediated cytoplasmic incompatibility: what have we learned in 50 years? eLife 9, e61989 (2020).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR8\">Lau, M. J., Ross, P. A. &amp; Hoffmann, A. A. Infertility and fecundity loss of Wolbachia-infected Aedes aegypti hatched from quiescent eggs is expected to alter invasion dynamics. PLoS Negl. Trop. Dis. 15, e0009179 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 8\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Infertility%20and%20fecundity%20loss%20of%20Wolbachia-infected%20Aedes%20aegypti%20hatched%20from%20quiescent%20eggs%20is%20expected%20to%20alter%20invasion%20dynamics&amp;journal=PLoS%20Negl.%20Trop.%20Dis.&amp;volume=15&amp;publication_year=2021&amp;author=Lau%2CMJ&amp;author=Ross%2CPA&amp;author=Hoffmann%2CAA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR9\">Maciel-de-Freitas, R. et al. Wolbachia strains wMel and wAlbB differentially affect Aedes aegypti traits related to fecundity. Microbiol. Spectr. 12, e0012824 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 9\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20strains%20wMel%20and%20wAlbB%20differentially%20affect%20Aedes%20aegypti%20traits%20related%20to%20fecundity&amp;journal=Microbiol.%20Spectr.&amp;volume=12&amp;publication_year=2024&amp;author=Maciel-de-Freitas%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR10\">Zug, R. &amp; Hammerstein, P. Bad guys turned nice? A critical assessment of Wolbachia mutualisms in arthropod hosts. Biol. Rev. Camb. Philos. Soc. 90, 89\u2013111 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 10\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Bad%20guys%20turned%20nice%3F%20A%20critical%20assessment%20of%20Wolbachia%20mutualisms%20in%20arthropod%20hosts&amp;journal=Biol.%20Rev.%20Camb.%20Philos.%20Soc.&amp;volume=90&amp;pages=89-111&amp;publication_year=2015&amp;author=Zug%2CR&amp;author=Hammerstein%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR11\">Weeks, A. R., Turelli, M., Harcombe, W. R., Reynolds, K. T. &amp; Hoffmann, A. A. From parasite to mutualist: rapid evolution of Wolbachia in natural populations of Drosophila. PLoS Biol. 5, e114 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 11\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=From%20parasite%20to%20mutualist%3A%20rapid%20evolution%20of%20Wolbachia%20in%20natural%20populations%20of%20Drosophila&amp;journal=PLoS%20Biol.&amp;volume=5&amp;publication_year=2007&amp;author=Weeks%2CAR&amp;author=Turelli%2CM&amp;author=Harcombe%2CWR&amp;author=Reynolds%2CKT&amp;author=Hoffmann%2CAA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR12\">Fry, A. J., Palmer, M. R. &amp; Rand, D. M. Variable fitness effects of Wolbachia infection in Drosophila melanogaster. Heredity 93, 379\u2013389 (2004).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 12\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Variable%20fitness%20effects%20of%20Wolbachia%20infection%20in%20Drosophila%20melanogaster&amp;journal=Heredity&amp;volume=93&amp;pages=379-389&amp;publication_year=2004&amp;author=Fry%2CAJ&amp;author=Palmer%2CMR&amp;author=Rand%2CDM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR13\">Shropshire, J. D., Leigh, B. &amp; Bordenstein, S. R. Male age and Wolbachia dynamics: investigating how fast and why bacterial densities and cytoplasmic incompatibility strengths vary. mBio 12, e02998-21 (2021).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR14\">Zheng, X. et al. Incompatible and sterile insect techniques combined eliminate mosquitoes. Nature 572, 56\u201361 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 14\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Incompatible%20and%20sterile%20insect%20techniques%20combined%20eliminate%20mosquitoes&amp;journal=Nature&amp;volume=572&amp;pages=56-61&amp;publication_year=2019&amp;author=Zheng%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR15\">Lim, J. T. et al. Efficacy of Wolbachia-mediated sterility to reduce the incidence of dengue: a synthetic control study in Singapore. Lancet Microbe 5, e422\u2013e432 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 15\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Efficacy%20of%20Wolbachia-mediated%20sterility%20to%20reduce%20the%20incidence%20of%20dengue%3A%20a%20synthetic%20control%20study%20in%20Singapore&amp;journal=Lancet%20Microbe&amp;volume=5&amp;pages=e422-e432&amp;publication_year=2024&amp;author=Lim%2CJT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR16\">Zabalou, S. et al. Wolbachia-induced cytoplasmic incompatibility as a means for insect pest population control. Proc. Natl. Acad. Sci. USA 101, 15042\u201315045 (2004).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 16\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia-induced%20cytoplasmic%20incompatibility%20as%20a%20means%20for%20insect%20pest%20population%20control&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;volume=101&amp;pages=15042-15045&amp;publication_year=2004&amp;author=Zabalou%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR17\">Jin, P.-Y., Tian, L., Chen, L. &amp; Hong, X.-Y. Spider mites of agricultural importance in China, with focus on species composition during the last decade (2008\u20132017). Syst. Appl. Acarol. 23, 2087 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 17\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Spider%20mites%20of%20agricultural%20importance%20in%20China%2C%20with%20focus%20on%20species%20composition%20during%20the%20last%20decade%20%282008%E2%80%932017%29&amp;journal=Syst.%20Appl.%20Acarol.&amp;volume=23&amp;publication_year=2018&amp;author=Jin%2CP-Y&amp;author=Tian%2CL&amp;author=Chen%2CL&amp;author=Hong%2CX-Y\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR18\">Ullah, M. S., Gotoh, T. &amp; Lim, U. T. Life history parameters of three phytophagous spider mites, Tetranychus piercei, T. truncatus and T. bambusae (Acari: Tetranychidae). J. Asia-Pac. Entomol. 17, 767\u2013773 (2014).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 18\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Life%20history%20parameters%20of%20three%20phytophagous%20spider%20mites%2C%20Tetranychus%20piercei%2C%20T.%20truncatus%20and%20T.%20bambusae%20%28Acari%3A%20Tetranychidae%29&amp;journal=J.%20Asia-Pac.%20Entomol.&amp;volume=17&amp;pages=767-773&amp;publication_year=2014&amp;author=Ullah%2CMS&amp;author=Gotoh%2CT&amp;author=Lim%2CUT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR19\">Zhu, Y. X. et al. A change in the bacterial community of spider mites decreases fecundity on multiple host plants. MicrobiologyOpen 8, e00743 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 19\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20change%20in%20the%20bacterial%20community%20of%20spider%20mites%20decreases%20fecundity%20on%20multiple%20host%20plants&amp;journal=MicrobiologyOpen&amp;volume=8&amp;publication_year=2019&amp;author=Zhu%2CYX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR20\">Zhu, Y. X. et al. Incidence of facultative bacterial endosymbionts in spider mites associated with local environments and host plants. Appl. Environ. Microbiol. 84, e02546 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 20\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Incidence%20of%20facultative%20bacterial%20endosymbionts%20in%20spider%20mites%20associated%20with%20local%20environments%20and%20host%20plants&amp;journal=Appl.%20Environ.%20Microbiol.&amp;volume=84&amp;publication_year=2018&amp;author=Zhu%2CYX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR21\">Zhang, Y. K., Chen, Y. T., Yang, K., Qiao, G. X. &amp; Hong, X. Y. Screening of spider mites (Acari: Tetranychidae) for reproductive endosymbionts reveals links between co-infection and evolutionary history. Sci. Rep. 6, 27900 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 21\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Screening%20of%20spider%20mites%20%28Acari%3A%20Tetranychidae%29%20for%20reproductive%20endosymbionts%20reveals%20links%20between%20co-infection%20and%20evolutionary%20history&amp;journal=Sci.%20Rep.&amp;volume=6&amp;publication_year=2016&amp;author=Zhang%2CYK&amp;author=Chen%2CYT&amp;author=Yang%2CK&amp;author=Qiao%2CGX&amp;author=Hong%2CXY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR22\">Yang, K. et al. Wolbachia dominate Spiroplasma in the co-infected spider mite Tetranychus truncatus. Insect Mol. Biol. 29, 19\u201337 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 22\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20dominate%20Spiroplasma%20in%20the%20co-infected%20spider%20mite%20Tetranychus%20truncatus&amp;journal=Insect%20Mol.%20Biol.&amp;volume=29&amp;pages=19-37&amp;publication_year=2020&amp;author=Yang%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR23\">Xia, X. et al. Wolbachia affects reproduction in the spider mite Tetranychus truncatus (Acari: Tetranychidae) by regulating chorion protein S38-like and Rop. Insect Mol. Biol. 30, 18\u201329 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 23\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20affects%20reproduction%20in%20the%20spider%20mite%20Tetranychus%20truncatus%20%28Acari%3A%20Tetranychidae%29%20by%20regulating%20chorion%20protein%20S38-like%20and%20Rop&amp;journal=Insect%20Mol.%20Biol.&amp;volume=30&amp;pages=18-29&amp;publication_year=2021&amp;author=Xia%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR24\">Zhu, Y. X., Song, Z. R., Zhang, Y. Y., Hoffmann, A. A. &amp; Hong, X. Y. Spider mites singly infected with either Wolbachia or Spiroplasma have reduced thermal tolerance. Front. Microbiol. 12, 706321 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 24\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Spider%20mites%20singly%20infected%20with%20either%20Wolbachia%20or%20Spiroplasma%20have%20reduced%20thermal%20tolerance&amp;journal=Front.%20Microbiol.&amp;volume=12&amp;publication_year=2021&amp;author=Zhu%2CYX&amp;author=Song%2CZR&amp;author=Zhang%2CYY&amp;author=Hoffmann%2CAA&amp;author=Hong%2CXY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR25\">Zhang, Q., Dou, W., Taning, C. N. T., Smagghe, G. &amp; Wang, J. J. Regulatory roles of microRNAs in insect pests: prospective targets for insect pest control. Curr. Opin. Biotechnol. 70, 158\u2013166 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 25\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Regulatory%20roles%20of%20microRNAs%20in%20insect%20pests%3A%20prospective%20targets%20for%20insect%20pest%20control&amp;journal=Curr.%20Opin.%20Biotechnol.&amp;volume=70&amp;pages=158-166&amp;publication_year=2021&amp;author=Zhang%2CQ&amp;author=Dou%2CW&amp;author=Taning%2CCNT&amp;author=Smagghe%2CG&amp;author=Wang%2CJJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR26\">Lucas, K. &amp; Raikhel, A. S. Insect microRNAs: biogenesis, expression profiling and biological functions. Insect Biochem. Mol. Biol. 43, 24\u201338 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 26\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Insect%20microRNAs%3A%20biogenesis%2C%20expression%20profiling%20and%20biological%20functions&amp;journal=Insect%20Biochem.%20Mol.%20Biol.&amp;volume=43&amp;pages=24-38&amp;publication_year=2013&amp;author=Lucas%2CK&amp;author=Raikhel%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR27\">Asgari, S. Role of microRNAs in insect host-microorganism interactions. Front Physiol. 2, 48 (2011).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 27\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Role%20of%20microRNAs%20in%20insect%20host-microorganism%20interactions&amp;journal=Front%20Physiol.&amp;volume=2&amp;publication_year=2011&amp;author=Asgari%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR28\">Lozano, J., Montanez, R. &amp; Belles, X. MiR-2 family regulates insect metamorphosis by controlling the juvenile hormone signaling pathway. Proc. Natl. Acad. Sci. USA 112, 3740\u20133745 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 28\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=MiR-2%20family%20regulates%20insect%20metamorphosis%20by%20controlling%20the%20juvenile%20hormone%20signaling%20pathway&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;volume=112&amp;pages=3740-3745&amp;publication_year=2015&amp;author=Lozano%2CJ&amp;author=Montanez%2CR&amp;author=Belles%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR29\">Zhang, S. et al. Host miRNAs are involved in hormonal regulation of HaSNPV-triggered climbing behaviour in Helicoverpa armigera. Mol. Ecol. 27, 459\u2013475 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 29\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Host%20miRNAs%20are%20involved%20in%20hormonal%20regulation%20of%20HaSNPV-triggered%20climbing%20behaviour%20in%20Helicoverpa%20armigera&amp;journal=Mol.%20Ecol.&amp;volume=27&amp;pages=459-475&amp;publication_year=2018&amp;author=Zhang%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR30\">Belles, X. MicroRNAs and the evolution of insect metamorphosis. Annu. Rev. Entomol. 62, 111\u2013125 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 30\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=MicroRNAs%20and%20the%20evolution%20of%20insect%20metamorphosis&amp;journal=Annu.%20Rev.%20Entomol.&amp;volume=62&amp;pages=111-125&amp;publication_year=2017&amp;author=Belles%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR31\">Lu, M. Y. &amp; Chtarbanova, S. The role of micro RNAs (miRNAs) in the regulation of Drosophila melanogaster\u2019s innate immunity. Fly 16, 382\u2013396 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 31\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20role%20of%20micro%20RNAs%20%28miRNAs%29%20in%20the%20regulation%20of%20Drosophila%20melanogaster%E2%80%99s%20innate%20immunity&amp;journal=Fly&amp;volume=16&amp;pages=382-396&amp;publication_year=2022&amp;author=Lu%2CMY&amp;author=Chtarbanova%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR32\">Xie, J. et al. miR-275\/305 cluster is essential for maintaining energy metabolic homeostasis by the insulin signaling pathway in Bactrocera dorsalis. PLoS Genet. 18, e1010418 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 32\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=miR-275%2F305%20cluster%20is%20essential%20for%20maintaining%20energy%20metabolic%20homeostasis%20by%20the%20insulin%20signaling%20pathway%20in%20Bactrocera%20dorsalis&amp;journal=PLoS%20Genet.&amp;volume=18&amp;publication_year=2022&amp;author=Xie%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR33\">Zhang, Y. et al. Insect-specific microRNA Involved in the development of the silkworm Bombyx mori. PLoS ONE 4, e4677 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 33\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Insect-specific%20microRNA%20Involved%20in%20the%20development%20of%20the%20silkworm%20Bombyx%20mori&amp;journal=PLoS%20ONE&amp;volume=4&amp;publication_year=2009&amp;author=Zhang%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR34\">Roy, S., Saha, T. T., Zou, Z. &amp; Raikhel, A. S. Regulatory pathways controlling female insect reproduction. Annu. Rev. Entomol. 63, 489\u2013511 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 34\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Regulatory%20pathways%20controlling%20female%20insect%20reproduction&amp;journal=Annu.%20Rev.%20Entomol.&amp;volume=63&amp;pages=489-511&amp;publication_year=2018&amp;author=Roy%2CS&amp;author=Saha%2CTT&amp;author=Zou%2CZ&amp;author=Raikhel%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR35\">Lucas, K. J., Zhao, B., Liu, S. &amp; Raikhel, A. S. Regulation of physiological processes by microRNAs in insects. Curr. Opin. Insect Sci. 11, 1\u20137 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 35\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Regulation%20of%20physiological%20processes%20by%20microRNAs%20in%20insects&amp;journal=Curr.%20Opin.%20Insect%20Sci.&amp;volume=11&amp;pages=1-7&amp;publication_year=2015&amp;author=Lucas%2CKJ&amp;author=Zhao%2CB&amp;author=Liu%2CS&amp;author=Raikhel%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR36\">Ling, L., Kokoza, V. A., Zhang, C., Aksoy, E. &amp; Raikhel, A. S. MicroRNA-277 targets insulin-like peptides 7 and 8 to control lipid metabolism and reproduction in Aedes aegypti mosquitoes. Proc. Natl. Acad. Sci. USA 114, E8017\u2013E8024 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 36\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=MicroRNA-277%20targets%20insulin-like%20peptides%207%20and%208%20to%20control%20lipid%20metabolism%20and%20reproduction%20in%20Aedes%20aegypti%20mosquitoes&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;volume=114&amp;pages=E8017-E8024&amp;publication_year=2017&amp;author=Ling%2CL&amp;author=Kokoza%2CVA&amp;author=Zhang%2CC&amp;author=Aksoy%2CE&amp;author=Raikhel%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR37\">Liu, L., Zhang, K. J., Rong, X., Li, Y. Y. &amp; Liu, H. Identification of Wolbachia-responsive miRNAs in the small brown planthopper, Laodelphax striatellus. Front. Physiol. 10, 928 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 37\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Identification%20of%20Wolbachia-responsive%20miRNAs%20in%20the%20small%20brown%20planthopper%2C%20Laodelphax%20striatellus&amp;journal=Front.%20Physiol.&amp;volume=10&amp;publication_year=2019&amp;author=Liu%2CL&amp;author=Zhang%2CKJ&amp;author=Rong%2CX&amp;author=Li%2CYY&amp;author=Liu%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR38\">Rong, X., Zhang, Y. K., Zhang, K. J. &amp; Hong, X. Y. Identification of Wolbachia-responsive microRNAs in the two-spotted spider mite, Tetranychus urticae. BMC Genomics 15, 1122 (2014).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 38\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Identification%20of%20Wolbachia-responsive%20microRNAs%20in%20the%20two-spotted%20spider%20mite%2C%20Tetranychus%20urticae&amp;journal=BMC%20Genomics&amp;volume=15&amp;publication_year=2014&amp;author=Rong%2CX&amp;author=Zhang%2CYK&amp;author=Zhang%2CKJ&amp;author=Hong%2CXY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR39\">Bishop, C., Hussain, M., Hugo, L. E. &amp; Asgari, S. Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity. Sci. Rep. 12, 15245 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 39\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Analysis%20of%20Aedes%20aegypti%20microRNAs%20in%20response%20to%20Wolbachia%20wAlbB%20infection%20and%20their%20potential%20role%20in%20mosquito%20longevity&amp;journal=Sci.%20Rep.&amp;volume=12&amp;publication_year=2022&amp;author=Bishop%2CC&amp;author=Hussain%2CM&amp;author=Hugo%2CLE&amp;author=Asgari%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR40\">Hussain, M., Frentiu, F. D., Moreira, L. A., O\u2019Neill, S. L. &amp; Asgari, S. Wolbachia uses host microRNAs to manipulate host gene expression and facilitate colonization of the dengue vector Aedes aegypti. Proc. Natl. Acad. Sci. USA 108, 9250\u20139255 (2011).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 40\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20uses%20host%20microRNAs%20to%20manipulate%20host%20gene%20expression%20and%20facilitate%20colonization%20of%20the%20dengue%20vector%20Aedes%20aegypti&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;volume=108&amp;pages=9250-9255&amp;publication_year=2011&amp;author=Hussain%2CM&amp;author=Frentiu%2CFD&amp;author=Moreira%2CLA&amp;author=O%E2%80%99Neill%2CSL&amp;author=Asgari%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR41\">Osei-Amo, S., Hussain, M., O\u2019Neill, S. L. &amp; Asgari, S. Wolbachia-induced aae-miR-12 miRNA negatively regulates the expression of MCT1 and MCM6 genes in Wolbachia-infected mosquito cell line. PLoS ONE 7, e50049 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 41\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia-induced%20aae-miR-12%20miRNA%20negatively%20regulates%20the%20expression%20of%20MCT1%20and%20MCM6%20genes%20in%20Wolbachia-infected%20mosquito%20cell%20line&amp;journal=PLoS%20ONE&amp;volume=7&amp;publication_year=2012&amp;author=Osei-Amo%2CS&amp;author=Hussain%2CM&amp;author=O%E2%80%99Neill%2CSL&amp;author=Asgari%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR42\">Wang, J. et al. XPO5 promotes primary miRNA processing independently of RanGTP. Nat. Commun. 11, 1845 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 42\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=XPO5%20promotes%20primary%20miRNA%20processing%20independently%20of%20RanGTP&amp;journal=Nat.%20Commun.&amp;volume=11&amp;publication_year=2020&amp;author=Wang%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR43\">Fast, E. M. et al. Wolbachia enhance Drosophila stem cell proliferation and target the germline stem cell niche. Science 334, 990\u2013992 (2011).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 43\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20enhance%20Drosophila%20stem%20cell%20proliferation%20and%20target%20the%20germline%20stem%20cell%20niche&amp;journal=Science&amp;volume=334&amp;pages=990-992&amp;publication_year=2011&amp;author=Fast%2CEM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR44\">Iovino, N., Pane, A. &amp; Gaul, U. miR-184 has multiple roles in Drosophila female germline development. Dev. Cell 17, 123\u2013133 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 44\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=miR-184%20has%20multiple%20roles%20in%20Drosophila%20female%20germline%20development&amp;journal=Dev.%20Cell&amp;volume=17&amp;pages=123-133&amp;publication_year=2009&amp;author=Iovino%2CN&amp;author=Pane%2CA&amp;author=Gaul%2CU\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR45\">Zhang, G., Hussain, M., O\u2019Neill, S. L. &amp; Asgari, S. Wolbachia uses a host microRNA to regulate transcripts of a methyltransferase, contributing to dengue virus inhibition in Aedes aegypti. Proc. Natl. Acad. Sci. USA 110, 10276\u201310281 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 45\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20uses%20a%20host%20microRNA%20to%20regulate%20transcripts%20of%20a%20methyltransferase%2C%20contributing%20to%20dengue%20virus%20inhibition%20in%20Aedes%20aegypti&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;volume=110&amp;pages=10276-10281&amp;publication_year=2013&amp;author=Zhang%2CG&amp;author=Hussain%2CM&amp;author=O%E2%80%99Neill%2CSL&amp;author=Asgari%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR46\">She, L. et al. Wolbachia mediates crosstalk between miRNA and Toll pathways to enhance resistance to dengue virus in Aedes aegypti. PLoS Pathog. 20, e1012296 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 46\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia%20mediates%20crosstalk%20between%20miRNA%20and%20Toll%20pathways%20to%20enhance%20resistance%20to%20dengue%20virus%20in%20Aedes%20aegypti&amp;journal=PLoS%20Pathog.&amp;volume=20&amp;publication_year=2024&amp;author=She%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR47\">Xia, X., Peng, C.-W., Lu, Y.-J., Zheng, X.-Y. &amp; Hong, X.-Y. Transfection and colonization of Tetranychus truncatus Wolbachia strain wTtru in cell lines of the mosquito Aedes albopictus. Syst. Appl. Acarol. 23, 2420\u20132431 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 47\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Transfection%20and%20colonization%20of%20Tetranychus%20truncatus%20Wolbachia%20strain%20wTtru%20in%20cell%20lines%20of%20the%20mosquito%20Aedes%20albopictus&amp;journal=Syst.%20Appl.%20Acarol.&amp;volume=23&amp;pages=2420-2431&amp;publication_year=2018&amp;author=Xia%2CX&amp;author=Peng%2CC-W&amp;author=Lu%2CY-J&amp;author=Zheng%2CX-Y&amp;author=Hong%2CX-Y\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR48\">He, Z. et al. How do Wolbachia modify the Drosophila ovary? New evidences support the \u201ctitration-restitution\u201d model for the mechanisms of Wolbachia-induced CI. BMC Genomics 20, 608 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 48\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=How%20do%20Wolbachia%20modify%20the%20Drosophila%20ovary%3F%20New%20evidences%20support%20the%20%E2%80%9Ctitration-restitution%E2%80%9D%20model%20for%20the%20mechanisms%20of%20Wolbachia-induced%20CI&amp;journal=BMC%20Genomics&amp;volume=20&amp;publication_year=2019&amp;author=He%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR49\">He, K. et al. Multiple miRNAs jointly regulate the biosynthesis of ecdysteroid in the holometabolous insects, Chilo suppressalis. RNA 23, 1817\u20131833 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 49\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multiple%20miRNAs%20jointly%20regulate%20the%20biosynthesis%20of%20ecdysteroid%20in%20the%20holometabolous%20insects%2C%20Chilo%20suppressalis&amp;journal=RNA&amp;volume=23&amp;pages=1817-1833&amp;publication_year=2017&amp;author=He%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR50\">Sun, K., Jee, D., de Navas, L. F., Duan, H. &amp; Lai, E. C. Multiple In vivo biological processes are mediated by functionally redundant activities of Drosophila mir-279 and mir-996. PLoS Genet. 11, e1005245 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 50\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multiple%20In%20vivo%20biological%20processes%20are%20mediated%20by%20functionally%20redundant%20activities%20of%20Drosophila%20mir-279%20and%20mir-996&amp;journal=PLoS%20Genet.&amp;volume=11&amp;publication_year=2015&amp;author=Sun%2CK&amp;author=Jee%2CD&amp;author=Navas%2CLF&amp;author=Duan%2CH&amp;author=Lai%2CEC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR51\">Wang, Y. L. et al. The microRNA miR-184 regulates the CYP303A1 transcript level to control molting of Locusta migratoria. Insect Sci. 28, 941\u2013951 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 51\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20microRNA%20miR-184%20regulates%20the%20CYP303A1%20transcript%20level%20to%20control%20molting%20of%20Locusta%20migratoria&amp;journal=Insect%20Sci.&amp;volume=28&amp;pages=941-951&amp;publication_year=2021&amp;author=Wang%2CYL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR52\">Feng, K. et al. Cuticle protein mediates the evolution of stress resistance by generating a decoy circular RNA in spider mite. Sci. Adv. 11, eads3361 (2025).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 52\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cuticle%20protein%20mediates%20the%20evolution%20of%20stress%20resistance%20by%20generating%20a%20decoy%20circular%20RNA%20in%20spider%20mite&amp;journal=Sci.%20Adv.&amp;volume=11&amp;publication_year=2025&amp;author=Feng%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR53\">Baldo, L. et al. Multilocus sequence typing system for the endosymbiont Wolbachia pipientis. Appl. Environ. Microbiol. 72, 7098\u20137110 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 53\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multilocus%20sequence%20typing%20system%20for%20the%20endosymbiont%20Wolbachia%20pipientis&amp;journal=Appl.%20Environ.%20Microbiol.&amp;volume=72&amp;pages=7098-7110&amp;publication_year=2006&amp;author=Baldo%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR54\">Chen, L. et al. The genome sequence of a spider mite, Tetranychus truncatus, provides insights into interspecific host range variation and the genetic basis of adaptation to a low-quality host plant. Insect Sci. 30, 1208\u20131228 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 54\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20genome%20sequence%20of%20a%20spider%20mite%2C%20Tetranychus%20truncatus%2C%20provides%20insights%20into%20interspecific%20host%20range%20variation%20and%20the%20genetic%20basis%20of%20adaptation%20to%20a%20low-quality%20host%20plant&amp;journal=Insect%20Sci.&amp;volume=30&amp;pages=1208-1228&amp;publication_year=2023&amp;author=Chen%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR55\">Kim, D., Paggi, J. M., Park, C., Bennett, C. &amp; Salzberg, S. L. Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype. Nat. Biotechnol. 37, 907\u2013915 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 55\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Graph-based%20genome%20alignment%20and%20genotyping%20with%20HISAT2%20and%20HISAT-genotype&amp;journal=Nat.%20Biotechnol.&amp;volume=37&amp;pages=907-915&amp;publication_year=2019&amp;author=Kim%2CD&amp;author=Paggi%2CJM&amp;author=Park%2CC&amp;author=Bennett%2CC&amp;author=Salzberg%2CSL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR56\">Pertea, M. et al. StringTie enables improved reconstruction of a transcriptome from RNA-seq reads. Nat. Biotechnol. 33, 290\u2013295 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 56\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=StringTie%20enables%20improved%20reconstruction%20of%20a%20transcriptome%20from%20RNA-seq%20reads&amp;journal=Nat.%20Biotechnol.&amp;volume=33&amp;pages=290-295&amp;publication_year=2015&amp;author=Pertea%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR57\">Langmead, B., Trapnell, C., Pop, M. &amp; Salzberg, S. L. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome. Genome Biol. 10, R25 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 57\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Ultrafast%20and%20memory-efficient%20alignment%20of%20short%20DNA%20sequences%20to%20the%20human%20genome&amp;journal=Genome%20Biol.&amp;volume=10&amp;publication_year=2009&amp;author=Langmead%2CB&amp;author=Trapnell%2CC&amp;author=Pop%2CM&amp;author=Salzberg%2CSL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR58\">Friedlander, M. R., Mackowiak, S. D., Li, N., Chen, W. &amp; Rajewsky, N. miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res. 40, 37\u201352 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 58\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=miRDeep2%20accurately%20identifies%20known%20and%20hundreds%20of%20novel%20microRNA%20genes%20in%20seven%20animal%20clades&amp;journal=Nucleic%20Acids%20Res.&amp;volume=40&amp;pages=37-52&amp;publication_year=2012&amp;author=Friedlander%2CMR&amp;author=Mackowiak%2CSD&amp;author=Li%2CN&amp;author=Chen%2CW&amp;author=Rajewsky%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR59\">Wen, M., Shen, Y., Shi, S. &amp; Tang, T. miREvo: an integrative microRNA evolutionary analysis platform for next-generation sequencing experiments. BMC Bioinforma. 13, 140 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 59\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=miREvo%3A%20an%20integrative%20microRNA%20evolutionary%20analysis%20platform%20for%20next-generation%20sequencing%20experiments&amp;journal=BMC%20Bioinforma.&amp;volume=13&amp;publication_year=2012&amp;author=Wen%2CM&amp;author=Shen%2CY&amp;author=Shi%2CS&amp;author=Tang%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR60\">Rehmsmeier, M., Steffen, P., Hochsmann, M. &amp; Giegerich, R. Fast and effective prediction of microRNA\/target duplexes. RNA 10, 1507\u20131517 (2004).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 60\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Fast%20and%20effective%20prediction%20of%20microRNA%2Ftarget%20duplexes&amp;journal=RNA&amp;volume=10&amp;pages=1507-1517&amp;publication_year=2004&amp;author=Rehmsmeier%2CM&amp;author=Steffen%2CP&amp;author=Hochsmann%2CM&amp;author=Giegerich%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR61\">Enright, A. J. et al. MicroRNA targets in Drosophila. Genome Biol. 5, R1 (2003).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 61\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=MicroRNA%20targets%20in%20Drosophila&amp;journal=Genome%20Biol.&amp;volume=5&amp;publication_year=2003&amp;author=Enright%2CAJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR62\">Mann, M., Wright, P. R. &amp; Backofen, R. IntaRNA 2.0: enhanced and customizable prediction of RNA-RNA interactions. Nucleic Acids Res. 45, W435\u2013W439 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 62\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=IntaRNA%202.0%3A%20enhanced%20and%20customizable%20prediction%20of%20RNA-RNA%20interactions&amp;journal=Nucleic%20Acids%20Res.&amp;volume=45&amp;pages=W435-W439&amp;publication_year=2017&amp;author=Mann%2CM&amp;author=Wright%2CPR&amp;author=Backofen%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR63\">Young, M. D., Wakefield, M. J., Smyth, G. K. &amp; Oshlack, A. Gene ontology analysis for RNA-seq: accounting for selection bias. Genome Biol. 11, R14 (2010).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 63\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Gene%20ontology%20analysis%20for%20RNA-seq%3A%20accounting%20for%20selection%20bias&amp;journal=Genome%20Biol.&amp;volume=11&amp;publication_year=2010&amp;author=Young%2CMD&amp;author=Wakefield%2CMJ&amp;author=Smyth%2CGK&amp;author=Oshlack%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR64\">Mao, X., Cai, T., Olyarchuk, J. G. &amp; Wei, L. Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary. Bioinformatics 21, 3787\u20133793 (2005).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 64\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Automated%20genome%20annotation%20and%20pathway%20identification%20using%20the%20KEGG%20Orthology%20%28KO%29%20as%20a%20controlled%20vocabulary&amp;journal=Bioinformatics&amp;volume=21&amp;pages=3787-3793&amp;publication_year=2005&amp;author=Mao%2CX&amp;author=Cai%2CT&amp;author=Olyarchuk%2CJG&amp;author=Wei%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR65\">Sun, W., Jin, Y., He, L., Lu, W. C. &amp; Li, M. Suitable reference gene selection for different strains and developmental stages of the carmine spider mite, Tetranychus cinnabarinus, using quantitative real-time PCR. J. Insect Sci. 10, 208 (2010).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 65\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Suitable%20reference%20gene%20selection%20for%20different%20strains%20and%20developmental%20stages%20of%20the%20carmine%20spider%20mite%2C%20Tetranychus%20cinnabarinus%2C%20using%20quantitative%20real-time%20PCR&amp;journal=J.%20Insect%20Sci.&amp;volume=10&amp;publication_year=2010&amp;author=Sun%2CW&amp;author=Jin%2CY&amp;author=He%2CL&amp;author=Lu%2CWC&amp;author=Li%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR66\">Ghazy, N. A. et al. A leaf-mimicking method for oral delivery of bioactive substances into sucking arthropod herbivores. Front. Plant Sci. 11, 1218 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 66\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20leaf-mimicking%20method%20for%20oral%20delivery%20of%20bioactive%20substances%20into%20sucking%20arthropod%20herbivores&amp;journal=Front.%20Plant%20Sci.&amp;volume=11&amp;publication_year=2020&amp;author=Ghazy%2CNA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR67\">Phatak, P. &amp; Donahue, J. M. Biotinylated micro-RNA pull down assay for identifying miRNA targets. Bio Protoc. 7, e2253 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 67\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Biotinylated%20micro-RNA%20pull%20down%20assay%20for%20identifying%20miRNA%20targets&amp;journal=Bio%20Protoc.&amp;volume=7&amp;publication_year=2017&amp;author=Phatak%2CP&amp;author=Donahue%2CJM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR68\">Searle, S. R., Speed, F. M. &amp; Milliken, G. A. Population marginal means in the linear model: an alternative to least squares means.  Am. Stat. 34, 216\u2013221 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 68\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Population%20marginal%20means%20in%20the%20linear%20model%3A%20an%20alternative%20to%20least%20squares%20means&amp;journal=Am.%20Stat.&amp;volume=34&amp;pages=216-221&amp;publication_year=2012&amp;author=Searle%2CSR&amp;author=Speed%2CFM&amp;author=Milliken%2CGA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR69\">Brooks, M. E. et al. glmmTMB balances speed and flexibility among packages for zero-inflated generalized linear mixed modeling. The R Journal\u00a09, 378\u2013400 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 69\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=glmmTMB%20balances%20speed%20and%20flexibility%20among%20packages%20for%20zero-inflated%20generalized%20linear%20mixed%20modeling&amp;journal=The%20R%20Journal&amp;volume=9&amp;pages=378-400&amp;publication_year=2017&amp;author=Brooks%2CME\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR70\">Lenth R. V. et al. emmeans: estimated marginal means, aka least-squares means. R package version 1.11.0. <a href=\"https:\/\/CRAN.R-project.org\/package=emmeans\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/CRAN.R-project.org\/package=emmeans\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/CRAN.R-project.org\/package=emmeans<\/a>. (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR71\">Zhao, D. X., Zhang, X. F., Chen, D. S., Zhang, Y. K. &amp; Hong, X. Y. Wolbachia-host interactions: host mating patterns affect Wolbachia density dynamics. PLoS ONE 8, e66373 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 71\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Wolbachia-host%20interactions%3A%20host%20mating%20patterns%20affect%20Wolbachia%20density%20dynamics&amp;journal=PLoS%20ONE&amp;volume=8&amp;publication_year=2013&amp;author=Zhao%2CDX&amp;author=Zhang%2CXF&amp;author=Chen%2CDS&amp;author=Zhang%2CYK&amp;author=Hong%2CXY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n","protected":false},"excerpt":{"rendered":"Gotoh, T., Noda, H. &amp; Hong, X. Y. Wolbachia distribution and cytoplasmic incompatibility based on a survey of&hellip;\n","protected":false},"author":2,"featured_media":398069,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[81491,34661,3181,85,46,3183,141],"class_list":{"0":"post-398068","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-science","8":"tag-bacterial-genetics","9":"tag-entomology","10":"tag-general","11":"tag-il","12":"tag-israel","13":"tag-life-sciences","14":"tag-science"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/398068","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=398068"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/398068\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/398069"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=398068"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=398068"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=398068"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}