{"id":403216,"date":"2026-04-21T10:30:36","date_gmt":"2026-04-21T10:30:36","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/403216\/"},"modified":"2026-04-21T10:30:36","modified_gmt":"2026-04-21T10:30:36","slug":"soft-robotic-devices-for-cardiovascular-medicine","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/403216\/","title":{"rendered":"Soft robotic devices for cardiovascular medicine"},"content":{"rendered":"

Timmis, A. et al. European society of cardiology: cardiovascular disease statistics 2021. Eur. Heart J. 43, 716\u2013799 (2022).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zrinscak, D., Lorenzon, L., Maselli, M. & Cianchetti, M. Soft robotics for physical simulators, artificial organs and implantable assistive devices. Prog. Biomed. Eng. 5, 012002 (2023).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Singh, M. et al. Hemodynamic evaluation of biomaterial-based surgery for tetralogy of Fallot using a biorobotic heart, in silico, and ovine models. Sci. Transl. Med. 16, eadk2936 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Omisore, O. M. et al. A review on flexible robotic systems for minimally invasive surgery. IEEE Trans. Syst., Man, Cybern. Syst. 52, 631\u2013644 (2022).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Siontis, G. C. M. et al. Transcatheter aortic valve implantation vs. surgical aortic valve replacement for treatment of symptomatic severe aortic stenosis: an updated meta-analysis. Eur. Heart J. 40, 3143\u20133153 (2019).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Sunwoo, S.-H. et al. Soft bioelectronics for the management of cardiovascular diseases. Nat. Rev. Bioeng. 2, 8\u201324 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Friedman, P. et al. Performance and safety of the extravascular implantable cardioverter defibrillator through long-term follow-up: final results from the pivot al study. Circulation 151, 322\u2013332 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Runciman, M., Darzi, A. & Mylonas, G. P. Soft robotics in minimally invasive surgery. Soft Robot. 6, 423\u2013443 (2019).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Cianchetti, M., Laschi, C., Menciassi, A. & Dario, P. Biomedical applications of soft robotics. Nat. Rev. Mater. 3, 143\u2013153 (2018).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Proietti, T. et al. Restoring arm function with a soft robotic wearable for individuals with amyotrophic lateral sclerosis. Sci. Transl. Med. 15, eadd1504 (2023).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lee, H. C. et al. A fabrication strategy for millimeter-scale, self-sensing soft-rigid hybrid robots. Nat. Commun. 15, 8456 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Park, C., Ozturk, C. & Roche, E. T. Computational design of a soft robotic myocardium for biomimetic motion and function. Adv. Funct. Mater. 32, 2206734 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Roche, E. T. et al. Soft robotic sleeve supports heart function. Sci. Transl. Med. 9, eaaf3925 (2017).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Buckberg, G., Hoffman, J. I. E., Mahajan, A., Saleh, S. & Coghlan, C. Cardiac mechanics revisited. Circulation 118, 2571\u20132587 (2008).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Nagel, E. et al. Cardiac rotation and relaxation in patients with aortic valve stenosis. Eur. Heart J. 21, 582\u2013589 (2000).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Weymann, A. et al. Artificial muscles and soft robotic devices for treatment of end-stage heart failure. Adv. Mater. 35, 2207390 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Tavlasoglu, M., Jahollari, A., Amrahov, A. & Sahin, M. A. An instrument facilitates mitral valve repair training at home. Eur. J. Cardio-Thorac. Surg. 41, 940\u2013941 (2012).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang, D. D. et al. 3D printing, computational modeling, and artificial intelligence for structural heart disease. JACC Cardiovasc. Imaging 14, 41\u201360 (2021).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Leopaldi, A. M. et al. The dynamic cardiac biosimulator: a method for training physicians in beating-heart mitral valve repair procedures. J. Thorac. Cardiovasc. Surg. 155, 147\u2013155 (2018).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Smooth-On. Ecoflex\u2122 Series: super-soft, addition cure silicone rubbers. Product overview. smooth-on.com https:\/\/www.smooth-on.com\/tb\/files\/ECOFLEX_SERIES_TB.pdf<\/a> (2024).<\/p>\n

Xavier, M. S., Fleming, A. J. & Yong, Y. K. Finite element modeling of soft fluidic actuators: overview and recent developments. Adv. Intell. Syst. 3, 2000187 (2021).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Gunduz, S., Albadawi, H. & Oklu, R. Robotic devices for minimally invasive endovascular interventions: a new dawn for interventional radiology. Adv. Intell. Syst. 3, 2000181 (2021).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Medrano-Gracia, P. et al. A computational atlas of normal coronary artery anatomy. EuroIntervention 12, 845\u2013854 (2016).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Boufi, M. et al. Morphological analysis of healthy aortic arch. Eur. J. Vasc. Endovasc. Surg. 53, 663\u2013670 (2017).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hutchins, G. M., Miner, M. M. & Boitnott, J. K. Vessel caliber and branch-angle of human coronary artery branch-points. Circ. Res. 38, 572\u2013576 (1976).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rogatinsky, J. et al. A multifunctional soft robot for cardiac interventions. Sci. Adv. 9, eadi5559 (2023).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Gang, E. S. et al. Dynamically shaped magnetic fields: initial animal validation of a new remote electrophysiology catheter guidance and control system. Circ. Arrhythm. Electrophysiol. 4, 770\u2013777 (2011).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Gu, H. et al. Self-folding soft-robotic chains with reconfigurable shapes and functionalities. Nat. Commun. 14, 1263 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Deng, T., Wang, H., Chen, W., Wang, X. & Pfeifer, R. Development of a new cable-driven soft robot for cardiac ablation. In 2013 IEEE International Conference on Robotics and Biomimetics (ROBIO) 728\u2013733 (IEEE, 2013).<\/p>\n

Nguyen, C. C. et al. Bidirectional soft robotic catheter for arrhythmia treatment. In 2022 International Conference on Robotics and Automation, 9579\u20139585 (IEEE, 2022).<\/p>\n

Piskarev, Y. et al. A variable stiffness magnetic catheter made of a conductive phase-change polymer for minimally invasive surgery. Adv. Funct. Mater. 32, 2107662 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Mirzajani, H. & Kraft, M. Soft bioelectronics for heart monitoring. ACS Sens. 9, 4328\u20134363 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rawish, E., Schmidt, T., Eitel, I. & Frerker, C. Current status of catheter-based mitral valve replacement. Curr. Cardiol. Rep. 23, 95 (2021).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Han, J. J., Acker, M. A. & Atluri, P. Left ventricular assist devices. Circulation 138, 2841\u20132851 (2018).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhao, C., Park, J., Root, S. E. & Bao, Z. Skin-inspired soft bioelectronic materials, devices and systems. Nat. Rev. Bioeng. 2, 671\u2013690 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Qiu, R. et al. E-cardiac patch to sense and repair infarcted myocardium. Nat. Commun. 15, 4133 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Park, C. et al. An organosynthetic dynamic heart model with enhanced biomimicry guided by cardiac diffusion tensor imaging. Sci. Robot. 5, eaay9106 (2020).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Davies, J. et al. Soft robotic artificial left ventricle simulator capable of reproducing myocardial biomechanics. Sci. Robot. 9, eado4553 (2024).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Thompson, N. A., Shin, S., Kocheril, A. G., Hsiao-Wecksler, E. T. & Krishnan, G. Design and validation of a soft robotic simulator for transseptal puncture training. IEEE Trans. Biomed. Eng. 70, 3003\u20133014 (2023).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhou, Y. et al. Design and analysis of a novel bionic cardiac simulator. In 2018 IEEE International Conference on Information and Automation (ICIA), 1245\u20131250 (IEEE, 2018).<\/p>\n

Park, C., Singh, M., Saeed, M. Y., Nguyen, C. T. & Roche, E. T. Biorobotic hybrid heart as a benchtop cardiac mitral valve simulator. Device 2, 100217 (2024).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Demeersseman, N. et al. Activation of a soft robotic left ventricular phantom embedded in a closed-loop cardiovascular simulator: a computational and experimental analysis. Cardiovasc. Eng. Technol. 16, 34\u201351 (2025).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ueda, D., Suzumori, K., Nabae, H., Ishikawa, Y. & Oda, T. Soft robotic heart formed with a myocardial band for cardiac functions. Soft Robot. 12, 488\u2013497 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Chamberlain, E. R. Cardiac surgical trainer and method for making same. US Patent 20020061503-A1 (2002).<\/p>\n

Lorenzon, L. et al. Harnessing mechanical instabilities in the development of an efficient soft pump for an artificial heart ventricle simulator. IEEE\/ASME Trans. Mechatron. 29, 936\u2013946 (2024).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Gulbulak, U. & Ertas, A. Finite element driven design domain identification of a beating left ventricular simulator. Bioengineering 6, 83 (2019).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Singh, M. et al. Robotic right ventricle is a biohybrid platform that simulates right ventricular function in (patho)physiological conditions and intervention. Nat. Cardiovasc. Res. 2, 1310\u20131326 (2023).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Singh, M., Park, C. & Roche, E. T. Decellularization following fixation of explanted aortic valves as a strategy for preserving native mechanical properties and function. Front. Bioeng. Biotechnol. 9, 803183 (2021).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Yue, Z. et al. Kaempferol alleviates myocardial ischemia injury by reducing oxidative stress via the HDAC3-mediated Nrf2 signaling pathway. J. Adv. Res. 75, 755\u2013764 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hulsmans, M. et al. Recruited macrophages elicit atrial fibrillation. Science 381, 231\u2013239 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rosalia, L. et al. Soft robotic platform for progressive and reversible aortic constriction in a small-animal model. Sci. Robot. 9, eadj9769 (2024).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rosalia, L. et al. A soft robotic sleeve mimicking the haemodynamics and biomechanics of left ventricular pressure overload and aortic stenosis. Nat. Biomed. Eng. 6, 1134\u20131147 (2022).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rosalia, L. et al. Modulating cardiac hemodynamics using tunable soft robotic sleeves in a porcine model of HFpEF physiology for device testing applications. Adv. Funct. Mater. 34, 2310085 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Charles, C. J., Rademaker, M. T., Scott, N. J. A. & Richards, A. M. Large animal models of heart failure: reduced vs. preserved ejection fraction. Animals 10, 1906 (2020).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rosalia, L. et al. Soft robotic patient-specific hydrodynamic model of aortic stenosis and ventricular remodeling. Sci. Robot. 8, eade2184 (2023).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Miyagi, C. et al. Large animal models of heart failure with preserved ejection fraction. Heart Fail. Rev. 27, 595\u2013608 (2022).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lang, R. M. et al. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur. Heart J. Cardiovasc. Imaging 16, 233\u2013271 (2015).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Dodge, J. T., Brown, B. G., Bolson, E. L. & Dodge, H. T. Lumen diameter of normal human coronary arteries. Influence of age, sex, anatomic variation, and left ventricular hypertrophy or dilation. Circulation 86, 232\u2013246 (1992).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhang, Y., Liao, J., Chen, M., Li, X. & Jin, G. A multi-module soft robotic arm with soft actuator for minimally invasive surgery. Int. J. Med. Robot. Comput. Assist. Surg. 19, e2467 (2023).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang, H., Zhang, R., Chen, W., Wang, X. & Pfeifer, R. A cable-driven soft robot surgical system for cardiothoracic endoscopic surgery: preclinical tests in animals. Surg. Endosc. 31, 3152\u20133158 (2017).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhu, J. et al. Intelligent soft surgical robots for next-generation minimally invasive surgery. Adv. Intell. Syst. 3, 2100011 (2021).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Liu, X. Soft robot system for heart surgery. In 2020 IEEE International Conference on Artificial Intelligence and Information Systems (ICAIIS), 470\u2013475 (IEEE, 2020).<\/p>\n

Rus, D. & Tolley, M. T. Design, fabrication and control of soft robots. Nature 521, 467\u2013475 (2015).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hausladen, M. M. et al. Synthetic growth by self-lubricated photopolymerization and extrusion inspired by plants and fungi. Proc. Natl Acad. Sci. USA 119, e2201776119 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hawkes, E. W., Blumenschein, L. H., Greer, J. D. & Okamura, A. M. A soft robot that navigates its environment through growth. Sci. Robot. 2, eaan3028 (2017).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kim, N. G., Seo, D., Park, S. & Ryu, J. H. Self-retractable soft growing robots for reliable and fast retraction while preserving their inherent advantages. IEEE Robot. Autom. Lett. 9, 1082\u20131089 (2024).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Mao, L. et al. Magnetic steering continuum robot for transluminal procedures with programmable shape and functionalities. Nat. Commun. 15, 3759 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Morimoto, Y., Onoe, H. & Takeuchi, S. Biohybrid robot powered by an antagonistic pair of skeletal muscle tissues. Sci. Robot. 3, eaat4440 (2018).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Yang, B. et al. Reprogrammable soft actuation and shape-shifting via tensile jamming. Sci. Adv. 7, eabh2073 (2021).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Yun, G. et al. Electro-mechano responsive elastomers with self-tunable conductivity and stiffness. Sci. Adv. 9, eadf1141 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kanagaratnam, P. et al. Experience of robotic catheter ablation in humans using a novel remotely steerable catheter sheath. J. Interv. Card. Electrophysiol. 21, 19\u201326 (2008).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Shaikh, Z., Eilenberg, M. & Cohen, T. The Amigo\u2122 remote catheter system: from concept to bedside. J. Innov. Card. Rhythm Manag. 8, 2795\u20132802 (2017).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Phelan Iii, M. F., Tiryaki, M. E., Lazovic, J., Gilbert, H. & Sitti, M. Heat-mitigated design and Lorentz force-based steering of an MRI-driven microcatheter toward minimally invasive surgery. Adv. Sci. 9, 2105352 (2022).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kim, Y., Parada, G. A., Liu, S. & Zhao, X. Ferromagnetic soft continuum robots. Sci. Robot. 4, eaax7329 (2019).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Tiryaki, M. E., Elmac\u0131o\u011flu, Y. G. & Sitti, M. Magnetic guidewire steering at ultrahigh magnetic fields. Sci. Adv. 9, eadg6438 (2023).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Nguyen, C. C. et al. Development of a soft robotic catheter for vascular intervention surgery. Sens. Actuat. A Phys. 357, 114380 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Guan, F. et al. Iontronic tip-sensing guidewires. Nat. Biomed. Eng. https:\/\/doi.org\/10.1038\/s41551-025-01548-9<\/a> (2025).<\/p>\n

Zhang, M. et al. A magnetically actuated microcatheter with soft rotatable tip for enhanced endovascular access and treatment efficiency. Sci. Adv. 11, eadv1682 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rivkin, B. et al. Electronically integrated microcatheters based on self-assembling polymer films. Sci. Adv. 7, eabl5408 (2021).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Fan, J. et al. Magnetic fiber robots with multiscale functional structures at the distal end. Adv. Funct. Mater. 34, 2309424 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Han, M. et al. Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery. Nat. Biomed. Eng. 4, 997\u20131009 (2020).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kashyap, V. et al. Multilayer fabrication of durable catheter-deployable soft robotic sensor arrays for efficient left atrial mapping. Sci. Adv. 6, eabc6800 (2020).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hao, B. et al. Focused ultrasound enables selective actuation and Newton-level force output of untethered soft robots. Nat. Commun. 15, 5197 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zheng, J., Qi, R., Dai, C., Li, G. & Sang, M. Enzyme catalysis biomotor engineering of neutrophils for nanodrug delivery and cell-based thrombolytic therapy. ACS Nano 16, 2330\u20132344 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Shao, J. et al. Erythrocyte membrane modified Janus polymeric motors for thrombus therapy. ACS Nano 12, 4877\u20134885 (2018).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Li, Z. et al. Untethered & stiffness-tunable ferromagnetic liquid robots for cleaning thrombus in complex blood vessels. Adv. Mater. 36, 2409142 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang, Q. et al. Untethered miniature robots for minimally invasive thrombus treatment: from bench to clinical trials. Innovation 6, 100874 (2025).<\/p>\n

PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lee, W., Nam, J., Kim, J., Jung, E. & Jang, G. Effective locomotion and precise unclogging motion of an untethered flexible-legged magnetic robot for vascular diseases. IEEE Trans. Ind. Electron. 65, 1388\u20131397 (2018).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

van Vliet, G. M., Misra, S. & Venkiteswaran, V. K. A magnetically-actuated flexible capsule robot for untethered cardiovascular interventions. In 2022 IEEE 5th International Conference on Soft Robotics (RoboSoft), 583\u2013588 (IEEE, 2022).<\/p>\n

Zhang, W. et al. Amoeba-inspired magnetic venom microrobots. Small 19, 2207360 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang, B. et al. tPA-anchored nanorobots for in vivo arterial recanalization at submillimeter-scale segments. Sci. Adv. 10, eadk8970 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang, T. et al. Adaptive wireless millirobotic locomotion into distal vasculature. Nat. Commun. 13, 4465 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ansari, M. et al. An experimental investigation on shape memory polymer and metallic stents under bending and radial compression. Eng. Res. Express 2, 045012 (2020).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Yasmin, F., Vafadar, A. & Tolouei-Rad, M. Application of additive manufacturing in the development of polymeric bioresorbable cardiovascular stents: a review. Adv. Mater. Technol. 10, 2400210 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zong, J. et al. Advances in the development of biodegradable coronary stents: a translational perspective. Mater. Today Bio 16, 100368 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Herbert, R., Lim, H.-R., Rigo, B. & Yeo, W.-H. Fully implantable wireless batteryless vascular electronics with printed soft sensors for multiplex sensing of hemodynamics. Sci. Adv. 8, eabm1175 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Son, D. et al. Bioresorbable electronic stent integrated with therapeutic nanoparticles for endovascular diseases. ACS Nano 9, 5937\u20135946 (2015).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Gaudino, M. et al. Association of radial artery graft vs saphenous vein graft with long-term cardiovascular outcomes among patients undergoing coronary artery bypass grafting: a systematic review and meta-analysis. JAMA 324, 179\u2013187 (2020).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lu, D. et al. Bioresorbable wireless sensors as temporary implants for in vivo measurements of pressure. Adv. Funct. Mater. 30, 2003754 (2020).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ouyang, H. et al. A bioresorbable dynamic pressure sensor for cardiovascular postoperative care. Adv. Mater. 33, 2102302 (2021).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Tang, C. et al. Unconstrained piezoelectric vascular electronics for wireless monitoring of hemodynamics and cardiovascular health. Small 20, 2304752 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Boutry, C. M. et al. Biodegradable and flexible arterial-pulse sensor for the wireless monitoring of blood flow. Nat. Biomed. Eng. 3, 47\u201357 (2019).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Liu, Z. et al. Electronic vascular conduit for in situ identification of hemadostenosis and thrombosis in small animals and nonhuman primates. Nat. Commun. 16, 2671 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Li, J. et al. Multifunctional artificial artery from direct 3D printing with built-in ferroelectricity and tissue-matching modulus for real-time sensing and occlusion monitoring. Adv. Funct. Mater. 30, 2002868 (2020).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Cheng, S. et al. Electronic blood vessel. Matter 3, 1664\u20131684 (2020).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ma, Z. et al. Smart vascular grafts with integrated flow biosensors for hemodynamic real-time monitoring and vascular healthcare. ACS Nano 19, 7661\u20137676 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Park, K. et al. Resealable antithrombotic artificial vascular graft integrated with a self-healing blood flow sensor. ACS Nano 17, 7296\u20137310 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Sim, K. et al. An epicardial bioelectronic patch made from soft rubbery materials and capable of spatiotemporal mapping of electrophysiological activity. Nat. Electron. 3, 775\u2013784 (2020).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lee, W. et al. Nonthrombogenic, stretchable, active multielectrode array for electroanatomical mapping. Sci. Adv. 4, eaau2426 (2018).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Choi, S. et al. Highly conductive, stretchable and biocompatible Ag\u2013Au core\u2013sheath nanowire composite for wearable and implantable bioelectronics. Nat. Nanotechnol. 13, 1048\u20131056 (2018).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Park, J. et al. Electromechanical cardioplasty using a wrapped elasto-conductive epicardial mesh. Sci. Transl. Med. 8, 344ra386 (2016).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhang, L. et al. Skin-inspired, sensory robots for electronic implants. Nat. Commun. 15, 4777 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang, L. et al. Injectable and conductive cardiac patches repair infarcted myocardium in rats and minipigs. Nat. Biomed. Eng. 5, 1157\u20131173 (2021).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Pabari, P. A. et al. When is an optimization not an optimization? Evaluation of clinical implications of information content (signal-to-noise ratio) in optimization of cardiac resynchronization therapy, and how to measure and maximize it. Heart Fail. Rev. 16, 277\u2013290 (2011).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Viventi, J. et al. A conformal, bio-interfaced class of silicon electronics for mapping cardiac electrophysiology. Sci. Transl. Med. 2, 24ra22 (2010).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Mulpuru, S. K., Madhavan, M., McLeod, C. J., Cha, Y.-M. & Friedman, P. A. Cardiac pacemakers: function, troubleshooting, and management: part 1 of a 2-part series. J. Am. Coll. Cardiol. 69, 189\u2013210 (2017).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Choi, Y. S. et al. Fully implantable and bioresorbable cardiac pacemakers without leads or batteries. Nat. Biotechnol. 39, 1228\u20131238 (2021).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Choi, H. et al. Adhesive bioelectronics for sutureless epicardial interfacing. Nat. Electron. 6, 779\u2013789 (2023).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Bolonduro, O. A. et al. An integrated optogenetic and bioelectronic platform for regulating cardiomyocyte function. Adv. Sci. 11, 2402236 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Mendez, K. L. et al. SmartSleeve: a sutureless, soft robotic epicardial device that enables switchable on-off drug delivery in response to epicardial ECG sensing. Device 2, 100419 (2024).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Bonnemain, J., del Nido, P. J. & Roche, E. T. Direct cardiac compression devices to augment heart biomechanics and function. Annu. Rev. Biomed. Eng. 24, 137\u2013156 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Burkhoff, D., Sayer, G., Doshi, D. & Uriel, N. Hemodynamics of mechanical circulatory support. J. Am. Coll. Cardiol. 66, 2663\u20132674 (2015).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Almanza, M. et al. Feasibility of a dielectric elastomer augmented aorta. Adv. Sci. 8, 2001974 (2021).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Pirozzi, I. et al. Electrohydraulic vascular compression device (e-VaC) with integrated sensing and controls. Adv. Mater. Technol. 8, 2201196 (2023).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Abraham, W. T. et al. Ambulatory extra-aortic counterpulsation in patients with moderate to severe chronic heart failure. JACC Heart Fail. 2, 526\u2013533 (2014).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Martinez, T. et al. A novel soft cardiac assist device based on a dielectric elastomer augmented aorta: an in vivo study. Bioeng. Transl. Med. 8, e10396 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Schulz, A. et al. Preliminary results from the C-Pulse\u00ae OPTIONS HF European Multicenter post-market study. Med. Sci. Monit. Basic Res. 22, 14\u201319 (2016).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ji, A. et al. Development of a self-deploying extra-aortic compression device for medium-term hemodynamic stabilization: a feasibility study. Adv. Sci. 12, 2412120 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Kim, J., Lee, J., Song, S., Kang, S.-H. & Han, A. K. E-CAD: electroactive polymer-based cardiac assist device with low power consumption. Adv. Intell. Syst. 7, 2500076 (2025).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Phan, P. T. et al. Robotic cardiac compression device using artificial muscle filaments for the treatment of heart failure. Adv. Intell. Syst. 6, 2300464 (2024).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Saeed, M. Y. et al. Dynamic augmentation of left ventricle and mitral valve function with an implantable soft robotic device. JACC Basic Transl. Sci. 5, 229\u2013242 (2020).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Payne, C. J. et al. Soft robotic ventricular assist device with septal bracing for therapy of heart failure. Sci. Robot. 2, eaan6736 (2017).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Vis, A. et al. The ongoing quest for the first total artificial heart as destination therapy. Nat. Rev. Cardiol. 19, 813\u2013828 (2022).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Cohrs, N. H. et al. A soft total artificial heart\u2014first concept evaluation on a hybrid mock circulation. Artif. Organs 41, 948\u2013958 (2017).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Arfaee, M. et al. A soft robotic total artificial hybrid heart. Nat. Commun. 16, 5146 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Guex, L. G. et al. Increased longevity and pumping performance of an injection molded soft total artificial heart. Soft Robot. 8, 588\u2013593 (2021).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Arfaee, M. et al. Toward developing a compact total artificial heart using a soft robotic fluidic transmission system. Sci. Adv. 11, eadv4854 (2025).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wu, W. et al. On the understanding of dielectric elastomer and its application for all-soft artificial heart. Sci. Bull. 66, 981\u2013990 (2021).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Yoo, J., Chung, G. & Park, Y. Bio-inspired, miniaturized magnetic heart valve system for superior performance cardiovascular simulator. Adv. Mater. 37, 2419504 (2025).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Brown, N. C., Ames, D. C. & Mueller, J. Multimaterial extrusion 3D printing printheads. Nat. Rev. Mater. 10, 807\u2013825 (2025).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhou, L.-Y., Fu, J. & He, Y. A review of 3D printing technologies for soft polymer materials. Adv. Funct. Mater. 30, 2000187 (2020).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Sachyani Keneth, E., Kamyshny, A., Totaro, M., Beccai, L. & Magdassi, S. 3D printing materials for soft robotics. Adv. Mater. 33, 2003387 (2021).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zhou, C. et al. Submillimeter fiber robots capable of decoupled macro-micro motion for endoluminal manipulation. Sci. Adv. 10, eadr6428 (2024).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Abdelaziz, M. E. M. K. et al. Fiberbots: robotic fibers for high-precision minimally invasive surgery. Sci. Adv. 10, eadj1984 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Dreyfus, R. et al. Dexterous helical magnetic robot for improved endovascular access. Sci. Robot. 9, eadh0298 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Yan, Y. et al. Magnetically assisted soft milli-tools for occluded lumen morphology detection. Sci. Adv. 9, eadi3979 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Li, S. et al. Recent progress in contact force sensing techniques for cardiovascular interventional procedures. Adv. Mater. https:\/\/doi.org\/10.1002\/adma.202513239<\/a> (2025).<\/p>\n

Article<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Ren, B. et al. The critical technologies of vascular interventional robotic catheterization: a review. IEEE Sens. J. 23, 30051\u201330069 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Yuan, M. et al. Soft electronics for advanced infant monitoring. Mater. Today 75, 166\u2013186 (2024).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Takakuwa, M. et al. Device integration technology for practical flexible electronics systems. Adv. Funct. Mater. https:\/\/doi.org\/10.1002\/adfm.202514330<\/a> (2025).<\/p>\n

Article<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Nair, V. et al. Miniature battery-free bioelectronics. Science 382, eabn4732 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Liu, Z. et al. A self-powered intracardiac pacemaker in swine model. Nat. Commun. 15, 507 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Deng, J. et al. A bioadhesive pacing lead for atraumatic cardiac monitoring and stimulation in rodent and porcine models. Sci. Transl. Med. 16, eado9003 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Roels, E. et al. Processing of self-healing polymers for soft robotics. Adv. Mater. 34, 2104798 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Fauvre, L., Portinha, D., Fleury, E. & Ganachaud, F. Thermoplastic silicone elastomers as materials exhibiting high mechanical properties and\/or self-healing propensity. J. Adhes. Sci. Technol. 35, 2723\u20132735 (2021).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Mariello, M., Kim, K., Wu, K., Lacour, S. P. & Leterrier, Y. Recent advances in encapsulation of flexible bioelectronic implants: materials, technologies, and characterization methods. Adv. Mater. 34, 2201129 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Jupiter Endovascular. Press release. Jupiter endovascular closes oversubscribed series B financing, surpassing $40 million target. jupiterendo.com https:\/\/jupiterendo.com\/jupiter-endovascular-closes-oversubscribed-series-b-financing-surpassing-40-million-target\/<\/a> (2025).<\/p>\n

Stereotaxis. Press release. Stereotaxis receives U.S. FDA clearance for MAGiC Sweep catheter. stereotaxis.com https:\/\/ir.stereotaxis.com\/news-releases\/news-release-details\/stereotaxis-receives-us-fda-clearance-magic-sweep-catheter<\/a> (2025).<\/p>\n

Cardiovascularnews. CorPath GRX robotic system receives FDA 510(k) clearance. cardiovascularnews.com https:\/\/cardiovascularnews.com\/corpath-grx-robotic-systems-receives-fda-510k-clearance\/<\/a> (2016).<\/p>\n

Johnson & Johnson MedTech. Press release. Biosense Webster launches the OCTARAY\u2122 mapping catheter with TRUEref\u2122 technology. jnjmedtech.com https:\/\/www.jnjmedtech.com\/en-US\/news-events\/biosense-webster-launches-octaray-mapping-catheter-trueref-technology<\/a> (2022).<\/p>\n

Johnson & Johnson MedTech. Press release. The evolving landscape of atrial fibrillation ablation: VARIPULSE\u2122 launches in European hospitals. jnjmedtech.com https:\/\/www.jnjmedtech.com\/en-EMEA\/news-events\/evolving-landscape-atrial-fibrillation-ablation-varipulse-launches-european-hospitals<\/a> (2024).<\/p>\n

Medtronic. Press release. Medtronic reports third quarter fiscal 2024 financial results. medtronic.com https:\/\/news.medtronic.com\/2024-02-20-Medtronic-reports-third-quarter-fiscal-2024-financial-results<\/a> (2024).<\/p>\n

Boston Scientific. Press release. Boston Scientific launches next generation of cardiac mapping for the FARAPULSE\u2122 pulsed field ablation system. bostonscientific.com https:\/\/news.bostonscientific.com\/2024-10-18-Boston-Scientific-Launches-Next-Generation-of-Cardiac-Mapping-for-the-FARAPULSE-TM-Pulsed-Field-Ablation-System<\/a> (2024).<\/p>\n

Stereotaxis. Press release. GenesisX robotic magnetic navigation system receives U.S. FDA clearance. stereotaxis.com https:\/\/ir.stereotaxis.com\/news-releases\/news-release-details\/genesisx-robotic-magnetic-navigation-system-receives-us-fda<\/a> (2025).<\/p>\n

Stereotaxis. Press release. Stereotaxis earns FDA clearance and announces U.S. launch of genesis robotic magnetic navigation system. stereotaxis.com https:\/\/ir.stereotaxis.com\/news-releases\/news-release-details\/stereotaxis-earns-fda-clearance-and-announces-us-launch-genesis<\/a> (2020).<\/p>\n

Baue, A. E., Tragus, E. T., Anstadt, G. L. & Blakemore, W. S. Mechanical ventricular assistance in man. Circulation 37, II-33\u2013II-36 (1968).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

PRWeb. German start-up AdjuCor marks milestone with successful first-in-human implantations of reBEAT system. prweb.com https:\/\/www.prweb.com\/releases\/german-start-up-adjucor-marks-milestone-with-successful-first-in-human-implantations-of-rebeat-system-301962827.html<\/a> (2023).<\/p>\n

Yu, C. et al. Chronological adhesive cardiac patch for synchronous mechanophysiological monitoring and electrocoupling therapy. Nat. Commun. 14, 6226 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Qu, J. et al. Advanced flexible sensing technologies for soft robots. Adv. Funct. Mater. 34, 2401311 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Hegde, C. et al. Sensing in soft robotics. ACS Nano 17, 15277\u201315307 (2023).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n PubMed<\/a>\u00a0
\n PubMed Central<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Liu, L. et al. Recent advances in flexible temperature sensors: materials, mechanism, fabrication, and applications. Adv. Sci. 11, 2405003 (2024).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n

Corsi, M. et al. Bioresorbable nanostructured chemical sensor for monitoring of pH level in vivo. Adv. Sci. 9, 2202062 (2022).<\/p>\n

Article<\/a>\u00a0
\n CAS<\/a>\u00a0
\n
\n Google Scholar<\/a>\u00a0\n <\/p>\n","protected":false},"excerpt":{"rendered":"Timmis, A. et al. European society of cardiology: cardiovascular disease statistics 2021. Eur. Heart J. 43, 716\u2013799 (2022).…\n","protected":false},"author":2,"featured_media":403217,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[34],"tags":[18004,190798,5248,45240,7305,3181,163,521,85,46,6134],"class_list":{"0":"post-403216","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-healthcare","8":"tag-biomaterials","9":"tag-cardiac-device-therapy","10":"tag-cardiac-imaging","11":"tag-cardiac-surgery","12":"tag-cardiology","13":"tag-general","14":"tag-health","15":"tag-healthcare","16":"tag-il","17":"tag-israel","18":"tag-medicine-public-health"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/403216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=403216"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/403216\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/403217"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=403216"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=403216"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=403216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}