{"id":439961,"date":"2026-05-13T17:39:13","date_gmt":"2026-05-13T17:39:13","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/439961\/"},"modified":"2026-05-13T17:39:13","modified_gmt":"2026-05-13T17:39:13","slug":"pitt-founded-startup-achieves-first-in-human-implant-of-nerve-pain-device","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/439961\/","title":{"rendered":"Pitt-Founded Startup Achieves First-in-Human Implant of Nerve Pain Device"},"content":{"rendered":"<p dir=\"ltr\">A medical device startup founded by University of Pittsburgh Swanson School of Engineering researchers has implanted its first human patient as part of an FDA-approved <a href=\"https:\/\/news.engineering.pitt.edu\/renerva-inc-approved-for-first-in-human-fda-clinical-trials\/\" target=\"_blank\" rel=\"nofollow noopener\">clinical study<\/a>, marking a major step toward commercialization of a technology designed to prevent chronic nerve pain.<\/p>\n<p dir=\"ltr\"><a href=\"http:\/\/www.renerva.com\" target=\"_blank\" rel=\"nofollow noopener\">Renerva, Inc.<\/a>, led by Chief Technology Officer Bryan Brown (BioE PhD &#8217;10), professor of bioengineering at Pitt&#8217;s Swanson School of Engineering, and CEO Lorenzo Soletti (BioE PhD &#8217;08), <a href=\"https:\/\/www.prnewswire.com\/news-releases\/renerva-achieves-first-in-human-implant-of-pnm-cap-device-for-neuroma-pain-302768652.html\" target=\"_blank\" rel=\"nofollow noopener\">successfully implanted<\/a> the first patient with its Renerva PNM-CAP\u2122 device at The Ohio State University (OSU) Wexner Medical Center. The procedure was led by Principal Investigator Amy M. Moore, MD, Interim Dean of the OSU College of Medicine.<\/p>\n<p dir=\"ltr\">&#8220;From a bioengineering perspective, we know that simply putting a mechanical block over a severed nerve isn&#8217;t enough to stop neuroma formation,&#8221; Brown said. \u201cPNM-CAP is engineered to intervene at the site of the nerve injury, guiding tissue repair in a way that stops uncontrolled nerve growth and entanglement before the onset of pain.&#8221;\u00a0<\/p>\n<p dir=\"ltr\">The Renerva PNM-CAP\u2122 is designed to prevent neuroma formation, a painful, disorganized nerve growth that commonly develops after amputation and other nerve injuries. Neuroma formation is a primary driver of chronic pain and opioid dependence among the more than two million Americans living with limb loss.<\/p>\n<p dir=\"ltr\">&#8220;This is a monumental milestone,&#8221; said Soletti. \u201cWe moved from FDA Investigational Device Exemption approval to first-in-human implantation in just a few months.&#8221;<\/p>\n<p>                        &#8216;;<\/p>\n","protected":false},"excerpt":{"rendered":"A medical device startup founded by University of Pittsburgh Swanson School of Engineering researchers has implanted its first&hellip;\n","protected":false},"author":2,"featured_media":439962,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[1352,114,181158,2664,85,46,181159],"class_list":["post-439961","post","type-post","status-publish","format-standard","has-post-thumbnail","category-business","tag-bioengineering","tag-business","tag-dept-banner","tag-features","tag-il","tag-israel","tag-pitt-swanson-school-of-engineering"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/439961","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=439961"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/439961\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/439962"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=439961"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=439961"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=439961"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}