{"id":468728,"date":"2026-05-31T05:16:31","date_gmt":"2026-05-31T05:16:31","guid":{"rendered":"https:\/\/www.newsbeep.com\/il\/468728\/"},"modified":"2026-05-31T05:16:31","modified_gmt":"2026-05-31T05:16:31","slug":"postbiotic-of-popular-strain-aids-weight-loss-maintenance","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/il\/468728\/","title":{"rendered":"Postbiotic of popular strain aids weight loss maintenance"},"content":{"rendered":"<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">In this edition of Supplement Shorts: an Akkermansia postbiotic helps with weight loss maintenance, research reviews provide insights on curcuminoids and vitamin B12, and dietary supplement industry companies announce executive appointments. Check out the supplement industry news, from scientific innovations to finished products and everything in between.<\/p>\n<p>Akkermansia postbiotic helpful for weight loss maintenance<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">An <a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link ContentText-BodyTextChunk_italic\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/s41591-026-04394-7\">Akkermansia<\/a><a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nature.com\/articles\/s41591-026-04394-7\"> postbiotic may support weight loss maintenance<\/a>, according to a Nature Medicine study.<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">Participants subscribed to a low-energy diet for eight weeks, followed by a maintenance period in which they supplemented with 30 billion heat-treated cells of Akkermansia muciniphila MucT (marketed by The Akkermansia Company) or placebo for 24 weeks.<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">Subjects supplementing with the postbiotic had lower weight regain and lost more weight compared to baseline versus those taking the placebo.<\/p>\n<p data-component=\"related-article\" class=\"RelatedArticle\">Related:<a class=\"RelatedArticle-RelatedContent\" href=\"https:\/\/www.supplysidesj.com\/supplements\/supplement-shorts-precision-grade-creatine-ingredient-launched\" target=\"_self\" data-discover=\"true\" rel=\"nofollow noopener\">Supplement Shorts: \u2018Precision-grade\u2019 creatine ingredient launched<\/a><\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">&#8220;Long-term weight maintenance remains one of the greatest unmet challenges in obesity management,&#8221; Willem M. de Vos, Ph.D., co-founder of The Akkermansia Company, said via <a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.prnewswire.com\/news-releases\/new-clinical-study-shows-pasteurized-akkermansia-muciniphila-muct-supports-weight-loss-maintenance-302776749.html\">press release<\/a>.<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">Researchers detected no changes in fasting glucagon-like peptide-1 (GLP-1) levels between the two groups, but impacts on insulin sensitivity were observed.<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">The eight-week low-energy diet resulted in improved insulin sensitivity \u2014 as measured by the <a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/oby.23503\">Matsuda Index<\/a> \u2014 for both groups, which held steady during the maintenance phase for those taking the postbiotic.<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">&#8220;These findings further strengthen the scientific understanding of Akkermansia muciniphila MucT and its potential role in supporting metabolic health,\u201d de Vos said.<\/p>\n<p>Clinical currents and science news<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">Vitamin B12 is a common component of many dietary supplements but the frequent use of large doses may not provide benefit, according to a <a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.mdpi.com\/2072-6643\/18\/10\/1597\">review on B12 clinical trials<\/a>. The authors wrote that \u201csupplementation has not shown consistent benefits in populations without overt clinical or biochemical B12 deficiency, with no clear improvements in fatigue, mood, cognition or cardiovascular outcomes.\u201d<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">The researchers also stated that higher circulating B12 levels link to \u201cincreased risk of malignancy,\u201d but findings are not consistent and more research is needed to draw a definitive conclusion.<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">The combination of curcumin and piperine helps not only with inflammation and oxidative stress but also supports cardiometabolic health. A <a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.frontiersin.org\/journals\/nutrition\/articles\/10.3389\/fnut.2026.1814168\/full\">systematic review of 20 randomized controlled trials<\/a> concluded the combination is consistently beneficial across a diverse clinical trial population with a well-established safety record. Formulators often pair piperine with curcuminoids to <a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41471123\/\">increase their bioavailability<\/a>.<\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">Krill oil may be more effective at increasing omega-3 levels versus fish oil.Participants supplemented with 1.1 g krill oil (marketed as SuperbaBoost by Aker Biomarine) or fish oil for 12 weeks. <a class=\"ContentText-BodyTextChunk ContentText-BodyTextChunk_link\" rel=\"noreferrer nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0002916526001553\">Krill oil supplementation resulted in a 1.5-fold increase<\/a> in EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid) compared to fish oil.<\/p>\n<p data-component=\"related-article\" class=\"RelatedArticle\">Related:<a class=\"RelatedArticle-RelatedContent\" href=\"https:\/\/www.supplysidesj.com\/supplements\/supplement-shorts-women-s-health-month-shines-light-on-life-stage-solutions\" target=\"_self\" data-discover=\"true\" rel=\"nofollow noopener\">Supplement Shorts: Women\u2019s Health Month shines light on life stage solutions<\/a><\/p>\n<p>Dietary supplement finished product newsCompany and organization updates<\/p>\n<p data-component=\"related-article\" class=\"RelatedArticle\">Related:<a class=\"RelatedArticle-RelatedContent\" href=\"https:\/\/www.supplysidesj.com\/supplements\/what-does-quality-mean-to-you-slideshow\" target=\"_self\" data-discover=\"true\" rel=\"nofollow noopener\">What does quality mean to you? \u2013 slideshow<\/a><\/p>\n<p class=\"ContentParagraph ContentParagraph_align_left\" data-testid=\"content-paragraph\">Launching innovative ingredients and products? Did you just publish a new clinical trial? Getting ready to announce something big? SupplySide Supplement Journal would love to know. Reach out to Devon at <a href=\"https:\/\/www.supplysidesj.com\/cdn-cgi\/l\/email-protection\" class=\"__cf_email__\" data-cfemail=\"badedfccd5d494ddd2d5d6dbd7fad3d4dcd5c8d7db94d9d5d7\" rel=\"nofollow noopener\" target=\"_blank\">[email\u00a0protected]<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"In this edition of Supplement Shorts: an Akkermansia postbiotic helps with weight loss maintenance, research reviews provide insights&hellip;\n","protected":false},"author":2,"featured_media":468729,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36],"tags":[163,85,46,543],"class_list":["post-468728","post","type-post","status-publish","format-standard","has-post-thumbnail","category-nutrition","tag-health","tag-il","tag-israel","tag-nutrition"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/468728","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/comments?post=468728"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/posts\/468728\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media\/468729"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/media?parent=468728"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/categories?post=468728"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/il\/wp-json\/wp\/v2\/tags?post=468728"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}